Results 21 to 30 of about 9,502 (198)

Expression of Alphavirus Nonstructural Protein 2 (nsP2) in Mosquito Cells Inhibits Viral RNA Replication in Both a Protease Activity-Dependent and -Independent Manner

Viruses, 2022
Alphaviruses are positive-strand RNA viruses, mostly being mosquito-transmitted. Cells infected by an alphavirus become resistant to superinfection due to a block that occurs at the level of RNA replication. Alphavirus replication proteins, called nsP1-4,
Liubov Cherkashchenko, Kai Rausalu, Sanjay Basu, Luke Alphey, Andres Merits   +4 more
doaj   +1 more source

Encephalitic alphaviruses [PDF]

Veterinary Microbiology, 2010
This review will cover zoonotic, encephalitic alphaviruses in the family Togaviridae. Encephalitic alphaviruses, i.e. Western- (WEEV), Eastern- (EEEV), Venezuelan equine encephalitis virus (VEEV) and, more rarely, Ross River virus, Chikungunya virus and Highlands J virus (HJV), are neuroinvasive and may cause neurological symptoms ranging from mild (e ...
Michele A, Zacks, Slobodan, Paessler
openaire   +2 more sources

An Investigation of Culicoides (Diptera: Ceratopogonidae) as Potential Vectors of Medically and Veterinary Important Arboviruses in South Africa

Viruses, 2021
Culicoides-borne viruses such as bluetongue, African horse sickness, and Schmallenberg virus cause major economic burdens due to animal outbreaks in Africa and their emergence in Europe and Asia.
Jumari Snyman, Gert J. Venter, Marietjie Venter   +2 more
doaj   +1 more source

Arthritogenic alphaviruses: epidemiological and clinical perspective on emerging arboviruses [PDF]

, 2020
Mosquito-borne viruses, or arboviruses, have been part of the infectious disease landscape for centuries, and are often, but not exclusively, endemic to equatorial and subtropical regions of the world.
Liu, Xiang, Burt, Felicity, Zaid, Ali, Mahalingam, Suresh, Zandi, Keivan, Suhrbier, Andreas, Weaver, Scott, Texeira, Mauro, Poo, Yee Suan   +8 more
core   +1 more source

Clinical Manifestations of Arthritogenic Alphaviruses [PDF]

, 2016
Increasing geographical range and the ability of alphaviruses to cause major disease outbreaks highlight their growing importance in clinical practice. Alphaviruses are now the most common cause of infectious arthritis worldwide.
Taylor, Adam, Suan Sin Foo, Roberts, Lynden, Foo, Jolin, Mahalingam, Suresh, Lynden Roberts, Adam Taylor, Lara J. Herrero, Herrero, Lara, Foo, Suan Sin, Ketheesan, Natkuman, Ketheesan, Natkunam, Natkunam Ketheesan, Suresh Mahalingam, Herrero, Lara J   +14 more
core   +1 more source

Encephalitic Alphaviruses [PDF]

, 2016
The family Togaviridae consists of two genera, Alphavirus and Rubivirus (Fields et al., 2013). The organization of their respective genomes is similar, but phylogenetic analysis shows that alphaviruses and rubiviruses are quite divergent (Koonin and ...
Clive S. McKimmie, John K. Fazakerley
openaire   +3 more sources

Establishment of an Alphavirus-Specific Neutralization Assay to Distinguish Infections with Different Members of the Semliki Forest complex

Viruses, 2019
Background: Alphaviruses are transmitted by arthropod vectors and can be found worldwide. Alphaviruses of the Semliki Forest complex such as chikungunya virus (CHIKV), Mayaro virus (MAYV) or Ross River virus (RRV) cause acute febrile illness and long ...
Lisa Henss, Constanze Yue, Joshua Kandler, Helen M. Faddy, Graham Simmons, Marcus Panning, Lia Laura Lewis-Ximenez, Sally A. Baylis, Barbara S. Schnierle   +8 more
doaj   +1 more source

Insect-Specific Chimeric Viruses Potentiated Antiviral Responses and Inhibited Pathogenic Alphavirus Growth in Mosquito Cells

Microbiology Spectrum, 2023
Most alphaviruses are transmitted by mosquito vectors and infect a wide range of vertebrate hosts, with a few exceptions. Eilat virus (EILV) in this genus is characterized by a host range restricted to mosquitoes. Its chimeric viruses have been developed
Lu Tan, Yiwen Zhang, Dal Young Kim, Runsheng Li   +3 more
doaj   +1 more source

Immunopathogenesis of alphaviruses

, 2020
Alphaviruses, members of the enveloped, positive-sense, single-stranded RNA Togaviridae family, represent a reemerging public health threat as mosquito vectors expand into new geographic territories. The Old World alphaviruses, which include chikungunya virus, Ross River virus, and Sindbis virus, tend to cause a clinical syndrome characterized by fever,
Victoria K, Baxter, Mark T, Heise
openaire   +3 more sources

Alphaviruses: Current Biology [PDF]

, 2016
Alphaviruses comprise a fascinating group of small, enveloped single-stranded positive-sense RNA viruses. They are usually transmitted by arthropod vectors (usually mosquitoes).
Mahalingam, Suresh, Herring, Belinda L, Herrero, Lara   +2 more
core   +1 more source