Results 11 to 20 of about 10,044 (209)
Alphaviruses Detected in Mosquitoes in the North-Eastern Regions of South Africa, 2014 to 2018 [PDF]
Viruses, 2023 The prevalence and distribution of African alphaviruses such as chikungunya have increased in recent years. Therefore, a better understanding of the local distribution of alphaviruses in vectors across the African continent is important.
Todd Johnson +2 more
exaly +6 more sources
Arthritogenic Alphaviruses: A Worldwide Emerging Threat?
Microorganisms, 2019 Arthritogenic alphaviruses are responsible for a dengue-like syndrome associated with severe debilitating polyarthralgia that can persist for months or years and impact life quality. Chikungunya virus is the most well-known member of this family since it
Marco Vignuzzi, Laura I Levi
exaly +4 more sources
VirusesChikungunya virus (CHIKV) and other alphaviruses that primarily induce arthritogenic disease in humans, known as “Old World” alphaviruses, present an emerging public health concern as geographic ranges of mosquito vectors expand due to climate change ...
Victoria Baxter, Alyssa M Lantz
exaly +4 more sources
Antiviral Strategies against Arthritogenic Alphaviruses
Microorganisms, 2020 Alphaviruses are members of the Togaviridae family that are mainly transmitted by arthropods such as mosquitoes. In the last decades, several alphaviruses have re-emerged, causing outbreaks worldwide. One example is the re-emergence of chikungunya virus (
Rana Abdelnabi, Leen Delang
doaj +2 more sources
Alphaviruses in Gene Therapy [PDF]
Viruses, 2009 Alphaviruses are enveloped single stranded RNA viruses, which as gene therapy vectors provide high-level transient gene expression. Semliki Forest virus (SFV), Sindbis virus (SIN) and Venezuelan Equine Encephalitis (VEE) virus have been engineered as efficient replication-deficient and -competent expression vectors.
Kenneth Lundstrom
openaire +7 more sources
Replication of Alphaviruses: A Review on the Entry Process of Alphaviruses into Cells [PDF]
Advances in Virology, 2011 Alphaviruses are small, enveloped viruses, ~70 nm in diameter, containing a single-stranded, positive-sense, RNA genome. Viruses belonging to this genus are predominantly arthropod-borne viruses, known to cause disease in humans. Their potential threat to human health was most recently exemplified by the 2005 Chikungunya virus outbreak in La Reunion ...
Jason Yat-Sing Leung +2 more
core +6 more sources
A High-Throughput Antiviral Assay Based on a Sindbis Virus-GFP for the Discovery of Inhibitors of Alphavirus Replication [PDF]
VirusesThe re-emergence of alphaviruses (family Togaviridae), such as chikungunya virus, poses significant public health risks, with direct impact on quality of life and work productivity.
Gabriel Augusto Pires de Souza +9 more
doaj +2 more sources
In silico reconstruction of a salmonid alphavirus virion reveals distinctive molecular features implicated in virulence [PDF]
iScienceSummary: Salmonid alphavirus (SAV) poses a significant disease threat to aquaculture. Recently, new alphaviruses from several fish species have been discovered. However, little is known about their biology and pathogenicity.
Stéphane Biacchesi +6 more
doaj +2 more sources
Infection of Mammals and Mosquitoes by Alphaviruses: Involvement of Cell Death
Cells, 2020 Alphaviruses, such as the chikungunya virus, are emerging and re-emerging viruses that pose a global public health threat. They are transmitted by blood-feeding arthropods, mainly mosquitoes, to humans and animals.
Carine Maisse
exaly +3 more sources
Activation of the PI3K-AKT Pathway by Old World Alphaviruses
Cells, 2020 Alphaviruses can infect a broad range of vertebrate hosts, including birds, horses, primates, and humans, in which infection can lead to rash, fever, encephalitis, and arthralgia or arthritis.
Eline Van Huizen, Gerald M. McInerney
doaj +2 more sources