Results 11 to 20 of about 12,699 (245)

Alphaviruses Detected in Mosquitoes in the North-Eastern Regions of South Africa, 2014 to 2018 [PDF]

open access: yesViruses, 2023
The prevalence and distribution of African alphaviruses such as chikungunya have increased in recent years. Therefore, a better understanding of the local distribution of alphaviruses in vectors across the African continent is important.
Milehna M. Guarido   +12 more
doaj   +5 more sources

Neuropathogenesis of Old World Alphaviruses: Considerations for the Development of Medical Countermeasures

open access: yesViruses
Chikungunya virus (CHIKV) and other alphaviruses that primarily induce arthritogenic disease in humans, known as “Old World” alphaviruses, present an emerging public health concern as geographic ranges of mosquito vectors expand due to climate change ...
Alyssa M. Lantz, Victoria K. Baxter
doaj   +3 more sources

Activation of the PI3K-AKT Pathway by Old World Alphaviruses

open access: yesCells, 2020
Alphaviruses can infect a broad range of vertebrate hosts, including birds, horses, primates, and humans, in which infection can lead to rash, fever, encephalitis, and arthralgia or arthritis.
Eline Van Huizen, Gerald M. McInerney
doaj   +3 more sources

Arthritogenic Alphaviruses: A Worldwide Emerging Threat?

open access: yesMicroorganisms, 2019
Arthritogenic alphaviruses are responsible for a dengue-like syndrome associated with severe debilitating polyarthralgia that can persist for months or years and impact life quality. Chikungunya virus is the most well-known member of this family since it
Laura I. Levi, Marco Vignuzzi
doaj   +3 more sources

Replication of Alphaviruses: A Review on the Entry Process of Alphaviruses into Cells [PDF]

open access: yesAdvances in Virology, 2011
Alphaviruses are small, enveloped viruses, ~70 nm in diameter, containing a single-stranded, positive-sense, RNA genome. Viruses belonging to this genus are predominantly arthropod-borne viruses, known to cause disease in humans.
Justin Jang Hann Chu   +6 more
core   +6 more sources

Alphaviruses in Gene Therapy [PDF]

open access: yesViruses, 2009
Alphaviruses are enveloped single stranded RNA viruses, which as gene therapy vectors provide high-level transient gene expression. Semliki Forest virus (SFV), Sindbis virus (SIN) and Venezuelan Equine Encephalitis (VEE) virus have been engineered as ...
Kenneth Lundstrom
core   +7 more sources

Alphaviruses in Cancer Therapy

open access: yesFrontiers in Molecular Biosciences, 2022
Alphaviruses have been engineered as expression vectors for different strategies of cancer therapy including immunotherapy and cancer vaccine development.
K. Lundstrom
semanticscholar   +4 more sources

Arthritogenic alphaviruses: epidemiological and clinical perspective on emerging arboviruses.

open access: yesLancet. Infectious Diseases (Print), 2020
Mosquito-borne viruses, or arboviruses, have been part of the infectious disease landscape for centuries, and are often, but not exclusively, endemic to equatorial and subtropical regions of the world.
Ali Zaid   +8 more
semanticscholar   +2 more sources

Immunopathogenesis of alphaviruses

open access: yesAdvances in Virus Research, 2020
Alphaviruses, members of the enveloped, positive-sense, single-stranded RNA Togaviridae family, represent a reemerging public health threat as mosquito vectors expand into new geographic territories.
V. K. Baxter, M. Heise
semanticscholar   +4 more sources

Seroprevalence of Alphaviruses (Togaviridae) among Urban Population in Nouakchott, Mauritania, West Africa

open access: yesViruses, 2023
The presence of alphaviruses, such as chikungunya virus (CHIKV), has never been reported in Mauritania. We assessed the seroprevalence of CHIKV among Nouakchott residents.
Bedia Abdoullah   +8 more
semanticscholar   +3 more sources

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