Results 51 to 60 of about 13,213 (215)

Sea Lice (Lepeophtheirus salmonis) Harbour Putative Fish Pathogens: Insights From Illumina and Nanopore Sequencing

Journal of Fish Diseases, EarlyView.
ABSTRACT Ectoparasites that penetrate host skin can act as biological or mechanical vectors for pathogens and, in some cases, serve as reservoirs. Crustacean ectoparasites of fish are potential vectors of pathogens, which is especially relevant for obligate pathogens (e.g., Aeromonas salmonicida) with limited seawater survival. Sea lice (Lepeophtheirus
B. Klimesova, N. M. Ruane, R. Domingo‐Bretón, F. Moroni, F. Naya‐Català, J. Pérez‐Sánchez, K. O'Dwyer, O. Lyashevska, H. Rodger, A. Talbot   +9 more
wiley   +1 more source

Self-Replicating Alphaviruses: From Pathogens to Therapeutic Agents

Viruses
Alphaviruses are known for being model viruses for studying cellular functions related to viral infections but also for causing epidemics in different parts of the world.
Kenneth Lundstrom
doaj   +1 more source

Role of autophagy during the replication and pathogenesis of common mosquito-borne flavi- and alphaviruses [PDF]

Open Biology, 2019
Arboviruses that are transmitted to humans by mosquitoes represent one of the most important causes of febrile illness worldwide. In recent decades, we have witnessed a dramatic re-emergence of several mosquito-borne arboviruses, including dengue virus ...
Liliana Echavarria-Consuegra, Jolanda M. Smit, Fulvio Reggiori   +2 more
doaj   +1 more source

Dengue Virus Capsid Protein Interaction With Nucleic Acids

BioFactors, Volume 52, Issue 3, May/June 2026.
Binding of dengue virus capsid protein (DENV C) to ssDNA alters Trp fluorescence intensity, lifetime, and anisotropy, revealing structural rearrangements in the complex and suggesting a possible association with liquid–liquid phase separation (LLPS). ABSTRACT Dengue virus (DENV) transmission has greatly increased in the last decade, partly due to the ...
Nelly M. Silva, Ana S. Martins, Nina E. Karguth, Maria J. Sarmento, Francisco J. Enguita, Roland G. Huber, Ivo C. Martins, Nuno C. Santos   +7 more
wiley   +1 more source

Mapping of RNA- temperature-sensitive mutants of Sindbis virus: assignment of complementation groups A, B, and G to nonstructural proteins [PDF]

, 1989
Four complementation groups of temperature-sensitive (ts) mutants of Sindbis virus that fail to make RNA at the nonpermissive temperature are known, and we have previously shown that group F mutants have defects in nsP4.
Hahn, Young S., Strauss, Ellen G., Strauss, James H.   +2 more
core   +1 more source

Visualization of membrane protein domains by cryo-electron microscopy of dengue virus [PDF]

, 2003
Improved technology for reconstructing cryo-electron microscopy (cryo-EM) images has now made it possible to determine secondary structural features of membrane proteins in enveloped viruses.
AJ Johnson, BD Lindenbach, BU Barth, CT Jones, DLD Caspar, DS Burke, DWC Beasley, EJ Mancini, FA Rey, FX Heinz, GW Smith, IC Lorenz, J Lescar, James H Strauss, Jeroen Corver, JH Strauss, JH Strauss, JJB Cockburn, JT Roehrig, K Stiasny, LJ McGuffin, MG Rossmann, MG Rossmann, Michael G Rossmann, ML Ng, N Grigorieff, Paul R Chipman, Peter R Johnson, PJL Werten, Richard J Kuhn, RJ Kuhn, S Bhardwaj, S Elshuber, S Lee, SL Allison, SL Allison, Suchetana Mukhopadhyay, T Solomon, Timothy S Baker, U Skoging, VM Unger, W Zhang, WD Crill, Wei Zhang, Y Ji, Y Modis, Y Zhang, Ying Zhang, YS Hahn   +48 more
core   +1 more source

Circulation of 2 Barmah Forest Virus Lineages in Military Training Areas, Australia

Emerging Infectious Diseases, 2020
During 2017–2018, Barmah Forest virus was recovered from mosquitoes trapped in military training areas in Australia and from a soldier infected at 1 of these areas.
Wenjun Liu, Joanne R. Kizu, David R. Matley, Richard Grant, Fiona J. McCallum, Christopher G. Moller, Tracy L. Carthew, Jun Hang, Ania J. Gubala, John G. Aaskov   +9 more
doaj   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Arboviruses and the challenge to establish systemic and persistent infections in competent mosquito vectors : the interaction with the RNAi mechanism [PDF]

, 2019
Arboviruses are capable to establish long-term persistent infections in mosquitoes that do not affect significantly the physiology of the insect vectors. Arbovirus infections are controlled by the RNAi machinery via the production of viral siRNAs and the
Kolliopoulou, Anna, Liu, Jisheng, Smagghe, Guy, Swevers, Luc   +3 more
core   +1 more source

First Record of Mosquito-Borne Kyzylagach Virus in Central Europe

Viruses, 2020
RNA of Kyzylagach virus (KYZV), a Sindbis-like mosquito-borne alphavirus from Western equine encephalitis virus complex, was detected in four pools (out of 221 pools examined), encompassing 10,784 female Culex modestus mosquitoes collected at a fishpond ...
Silvie Šikutová, Patrik Dočkal, Petra Straková, Jan Mendel, Oldřich Šebesta, Lenka Betášová, Hana Blažejová, Zdeněk Hubálek, Ivo Rudolf   +8 more
doaj   +1 more source