Results 51 to 60 of about 9,502 (198)

Alphavirus-Based Vaccines

Viruses, 2014
Alphavirus vectors have demonstrated high levels of transient heterologous gene expression both in vitro and in vivo and, therefore, possess attractive features for vaccine development.
Kenneth Lundstrom
doaj   +1 more source

Superinfection exclusion of alphaviruses in Aedes mosquitoes [PDF]

, 2021
© 2021 Mathilde LauretiChikungunya virus (CHIKV), Semliki Forest virus (SFV) and Ross River virus (RRV) are arthropod-borne alphaviruses transmitted by Aedes mosquitoes.
Laureti, Mathilde
core  

Alphaviruses in Immunotherapy and Anticancer Therapy [PDF]

, 2022
Alphaviruses have been engineered as expression vectors for vaccine development and gene therapy. Due to the feature of RNA self-replication, alphaviruses can provide exceptional direct cytoplasmic expression of transgenes based on the delivery of ...
Kenneth Lundstrom, Lundstrom, Kenneth
core   +1 more source

Vaccination Reduces Shedding of Salmonid Alphavirus Subtype 3, but Bacterial Co‐Infection Influences the Effect

Journal of Fish Diseases, EarlyView.
ABSTRACT Waterborne horizontal transmission of viral diseases in fish relies on the release of infectious virus particles (termed shedding) into the aquatic environment. Both the rate and duration of shedding are critical for efficient viral spread, making interventions that reduce shedding valuable for disease control.
Søren Grove, H. Craig Morton, Dhamotharan Kannimuthu, HyeongJin Roh, Ravikumar M. Chovatia, Ma Michelle Peñaranda, Dawit Ghebretnsae, Kai Ove Skaftnesmo   +7 more
wiley   +1 more source

Venezuelan Equine Encephalitis Complex Alphavirus in Bats, French Guiana

Emerging Infectious Diseases, 2021
Although essential for control strategies, knowledge about transmission cycles is limited for Venezuelan equine encephalitis complex alphaviruses (VEEVs).
Carlo Fischer, Dominique Pontier, Ondine Filippi-Codaccioni, Jean-Batiste Pons, Ignacio Postigo-Hidalgo, Jeanne Duhayer, Sebastian Brünink, Jan Felix Drexler   +7 more
doaj   +1 more source

An international study on emerging arboviral infections and blood safety

Transfusion, EarlyView.
Abstract Background Emerging and re‐emerging arboviral infections are a risk to blood safety. We conducted an international survey on how blood establishments respond to current and future arbovirus threats. Study Design and Methods A questionnaire on arbovirus donor deferral strategies, pathogen reduction, and donation screening was distributed to ...
Piya Rajendra, Helen M. Faddy, Daniel Candotti, Carolina B. Bub, Jose M. Kutner, Steven J. Drews, Carmen L. Charlton, Sheila F. O'Brien, Wai‐Chiu Tsoi, Michel‐Andres Garcia‐Otalora, Claire Reynolds, Tuulia Palukka, Riikka Lehtisalo, Ruth Offergeld, Axel Seltsam, Marijke Weber‐Schehl, Nahid Chenarsabz, Naoko Goto, Sung‐Chan Park, So‐Yong Kwon, Ryanne Lieshout‐Krikke, Aneta Kopacz, Ewa Sulkowska, Oana‐Alexandra Șerban, Simona Ruta, Eugene Zhiburt, Maha Badawi, Josephine Mitchel, Ute Jentsch, Ángel Luis Pajares Herraiz, Ana Lafuente Guijosa, Gülşen Özkaya Şahin, Christoph Niederhauser, Marion C. Lanteri, Brian Custer, Galen Conti, Anthea Cheng, Shannah Secret, Peter Simmonds, Heli Harvala, on behalf of the Virology subgroup of the ISBT WP‐TTID   +40 more
wiley   +1 more source

Mosquitoes as Suitable Vectors for Alphaviruses [PDF]

, 2018
Alphaviruses are arthropod-borne viruses and are predominantly transmitted via mosquito vectors. This vector preference by alphaviruses raises the important question of the determinants that contribute to vector competence.
Eugene Madzokere, Elisa Lim, Wai Suet Lee, Lim, Elisa XY, Lim, Elisa, Lara J. Herrero, Lara Herrero, Eugene T. Madzokere, Herrero, Lara, Elisa X. Y. Lim, Lee, Wai Suet, Wai Lee, Madzokere, Eugene, Herrero, Lara J, Madzokere, Eugene T   +14 more
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Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry

Viruses, 2019
Viruses are a major threat to human health and economic well-being. In recent years Ebola, Zika, influenza, and chikungunya virus epidemics have raised awareness that infections can spread rapidly before vaccines or specific antagonists can be made ...
Michela Mazzon, Ana Maria Ortega-Prieto, Douglas Imrie, Christin Luft, Lena Hess, Stephanie Czieso, Joe Grove, Jessica Katy Skelton, Laura Farleigh, Joachim J. Bugert, Edward Wright, Nigel Temperton, Richard Angell, Sally Oxenford, Michael Jacobs, Robin Ketteler, Marcus Dorner, Mark Marsh   +17 more
doaj   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

Zoonotic Alphaviruses in Fatal and Neurologic Infections in Wildlife and Nonequine Domestic Animals, South Africa [PDF]

, 2020
Alphaviruses from Africa, such as Middelburg virus (MIDV), and Sindbis virus (SINV), were detected in horses with neurologic disease in South Africa, but their host ranges remain unknown. We investigated the contribution of alphaviruses to neurologic
Elizabeth Botha, Marietjie Venter, Bjorn Reininghaus, Fourie, Isabel, Johan Steyl, Jumari Steyn, Voula Stivaktas, Isabel Fourie, Reininghaus, V., Steyl, Johan Christian Abraham, June Williams, Van Niekerk, Stephanie, Botha, Elizabeth, Venter, Marietjie, Steyn, Jumari, Williams, June Heather, Stivaktas, Voula, Stefanie van Niekerk   +17 more
core   +1 more source