Results 71 to 80 of about 10,044 (209)

Economic effects of disease outbreaks on U.S. salmonid farms

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract The U.S. salmonid industry is the second‐largest finfish sector of U.S. aquaculture, contributing $886 million and more than 2000 jobs to the U.S. economy in 2022. The goal of this study was to develop an economic analysis of the impact of losses from disease outbreaks to the U.S. salmonid industry.
Carole Engle, Shraddha Hegde, Jonathan van Senten, Ganesh Kumar, Christine Ellis, Gary Fornshell   +5 more
wiley   +1 more source

Host-Driven Ubiquitination Events in Vector-Transmitted RNA Virus Infections as Options for Broad-Spectrum Therapeutic Intervention Strategies

Viruses
Many vector-borne viruses are re-emerging as public health threats, yet our understanding of the virus–host interactions critical for productive infection remains limited. The ubiquitination of proteins, including host- and pathogen-derived proteins is a
Sanskruthi Sreepangi, Haseebullah Baha, Lorreta Aboagyewa Opoku, Naomi X. Jones, Maame Konadu, Farhang Alem, Michael D. Barrera, Aarthi Narayanan   +7 more
doaj   +1 more source

A customized program for the identification of conserved protein sequence motifs

BioTechniques, 2020
We searched for viral protein sequences that could be important for tissue tropism. To achieve this goal, human pathogenic viruses were classified according to the tissue they infect (e.g., pulmonary), irrespective of whether they were enveloped or non ...
Mohammad Mian, Jeffrey Talada, Anthony Klobas, Stephanie Torres, Yusuf Rasheed, Hibah Javed, Zainab Lughmani, Reza Forough   +7 more
doaj   +1 more source

Challenges and emerging trends in fish vaccine platforms, delivery methods, and field performance for sustainable aquaculture: A scoping review

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract Fish vaccination has been practiced globally for several decades and is increasingly recognized as a cornerstone of sustainable disease management in aquaculture, offering an effective alternative to antibiotic and chemotherapeutic use. This PRISMA‐ScR guided Scoping Review synthesized evidence from 173 peer‐reviewed studies and reports to ...
Fredrick Juma Syanya, Zachariy Oreko Winam, Paul Maina Mwangi, Harikrishnan Mahadevan, A. R. Nikhila Khanna, Mujeeb Rahiman K M, Megha Lovejan   +6 more
wiley   +1 more source

Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2 [PDF]

, 1998
Bcl-2 oncogene expression plays a role in the establishment of persistent viral infection by blocking virus-induced apoptosis. This might be achieved by preventing virus-induced activation of caspase-3, an IL-1beta-converting enzyme (ICE)-like cysteine ...
Grandgirard, Denis, Monney, Laurent, Borner, Christoph, Studer, Erwin, Belser, Tanja, Michel, Marcel R., Fellay, Isabelle   +6 more
core   +1 more source

Alphaviruses in Immunotherapy and Anticancer Therapy

, 2022
Alphaviruses have been engineered as expression vectors for vaccine development and gene therapy. Due to the feature of RNA self-replication, alphaviruses can provide exceptional direct cytoplasmic expression of transgenes based on the delivery of ...
Kenneth Lundstrom, Lundstrom, Kenneth
core   +1 more source

Structural insights into host-pathogen interactions of alphaviruses [PDF]

, 2020
Alphaviruses are arthropod-borne, single-stranded positive-sense RNA viruses of the Togaviridae family that infect various vertebrates worldwide in tropical and temperate areas, causing emerging and reemerging diseases in humans. Mature virions are 70 nm
Basore, Katherine
core   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, Volume 13, Issue 38, 9 July 2026.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

Macrophages as target cells for Mayaro virus infection: involvement of reactive oxygen species in the inflammatory response during virus replication

Anais da Academia Brasileira de Ciências
Alphaviruses among the viruses that cause arthritis, consisting in a public health problem worldwide by causing localized outbreaks, as well as large epidemics in humans.
MARIANA G. CAVALHEIRO, LEANDRO SILVA DA COSTA, HOLMES S. CAMPOS, LETÍCIA S. ALVES, IRANAIA ASSUNÇÃO-MIRANDA, ANDREA T. DA POIAN   +5 more
doaj   +1 more source

Land‐Based Functional Rehabilitation Versus Aquatic Therapy on the Quality of Life of Individuals With Chronic Chikungunya: A Randomized Clinical Trial

Physiotherapy Research International, Volume 31, Issue 3, July 2026.
ABSTRACT Background and Purpose Chikungunya may progress to a chronic phase marked by persistent pain and functional impairment, reducing the quality of life. Exercise‐based rehabilitation is essential, though comparisons between different modalities remain scarce. Exercises in an aquatic environment can be designed as a task‐oriented intervention that
Oliva Maria da Silva Sousa, Marynara Fabíola Silva Araújo, Geilson Medeiros de Araújo, Hilmaynne Renaly Fonseca Fialho, Renata Newman Leite dos Santos Lucena, Eleazar Marinho de Freitas Lucena   +5 more
wiley   +1 more source