Results 81 to 90 of about 13,213 (215)

Adaptive changes in alphavirus mRNA translation allowed colonization of vertebrate hosts [PDF]

open access: yes, 2012
Members of the Alphavirus genus are arboviruses that alternate replication in mosquitoes and vertebrate hosts. In vertebrate cells, the alphavirus resists the activation of antiviral RNA-activated protein kinase (PKR) by the presence of a prominent RNA
Ventoso, Iván
core   +2 more sources

Replication of Alphaviruses: A Review on the Entry Process of Alphaviruses into Cells [PDF]

open access: yesAdvances in Virology, 2011
Alphaviruses are small, enveloped viruses, ~70 nm in diameter, containing a single-stranded, positive-sense, RNA genome. Viruses belonging to this genus are predominantly arthropod-borne viruses, known to cause disease in humans. Their potential threat to human health was most recently exemplified by the 2005 Chikungunya virus outbreak in La Reunion ...
Jason Yat-Sing Leung   +2 more
openaire   +3 more sources

Borna disease virus infection: Retrospective case series of five horses and two donkeys in Switzerland

open access: yesEquine Veterinary Education, Volume 38, Issue 3, Page e119-e129, March 2026.
Summary Borna disease is an acute to subacute, rarely chronic non‐purulent meningoencephaylomyelitis affecting mainly horses and sheep. This case series describes the clinical signs, diagnosis, treatment, outcome and post‐mortem findings of five horses and two donkeys with this condition. The equids affected were geldings or mares of various breeds and
I. L. Piotrowski, M. Hilbe, H. K. Junge
wiley   +1 more source

Semliki Forest viiruse replikaasivalgu nsP1 uurimine [PDF]

open access: yes, 2013
Väitekirja elektrooniline versioon ei sisalda publikatsioone.Semliki Forest viirus kuulub alfaviiruste perekonda sugukonnas Togaviridae. Alfaviirused on olulised patogeenid ning põhjustavad erinevaid vaevusi nii loomadele kui ka inimestele.
Karo-Astover, Liis
core  

A Viral mRNA Motif at the 3′-Untranslated Region that Confers Translatability in a Cell-Specific Manner. Implications for Virus Evolution [PDF]

open access: yes, 2016
Sindbis virus (SINV) mRNAs contain several motifs that participate in the regulation of their translation. We have discovered a motif at the 3′ untranslated region (UTR) of viral mRNAs, constituted by three repeated sequences, which is involved in the ...
Carrasco, Luis   +2 more
core   +2 more sources

LDL receptor in alphavirus entry: structural analysis and implications for antiviral therapy

open access: yesNature Communications
Various low-density lipoprotein receptors (LPRs) have been identified as entry factors for alphaviruses, and structures of the corresponding virion-receptor complexes have been determined. Here, we analyze the similarities and differences in the receptor
Ningning Wang   +10 more
doaj   +1 more source

Macrophages as target cells for Mayaro virus infection: involvement of reactive oxygen species in the inflammatory response during virus replication

open access: yesAnais da Academia Brasileira de Ciências
Alphaviruses among the viruses that cause arthritis, consisting in a public health problem worldwide by causing localized outbreaks, as well as large epidemics in humans.
MARIANA G. CAVALHEIRO   +5 more
doaj   +1 more source

Viral Disease Histopathology in Aquaculture Finfish: Organ‐Specific Pathological Changes and Diagnostic Insights, Referencing the World Organisation for Animal Health: A Review

open access: yesReviews in Aquaculture, Volume 18, Issue 2, March 2026.
ABSTRACT The aquaculture industry faces significant challenges from viral diseases, many of which are listed by the World Organisation for Animal Health (WOAH) as priority pathogens due to their impact on global finfish health and production. This review synthesizes current knowledge on the histopathology of key WOAH‐listed viral pathogens, including ...
Ram Babu Kurapati   +4 more
wiley   +1 more source

hnRNP A1 interacts with the genomic and subgenomic RNA promoters of Sindbis virus and is required for the synthesis of G and SG RNA [PDF]

open access: yes, 2010
Background Sindbis virus (SV) is the prototype of alphaviruses which are a group of widely distributed human and animal pathogens. Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is an RNA-binding protein that shuttles between the nucleus ...
Hongxin Gui   +4 more
core   +2 more sources

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

open access: yesChemMedChem, Volume 21, Issue 4, 25 February 2026.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto   +12 more
wiley   +1 more source

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