Results 61 to 70 of about 10,044 (209)

Application of a Human Blood Brain Barrier Organ-on-a-Chip Model to Evaluate Small Molecule Effectiveness against Venezuelan Equine Encephalitis Virus

Viruses, 2022
The blood brain barrier (BBB) is a multicellular microenvironment that plays an important role in regulating bidirectional transport to and from the central nervous system (CNS).
Niloufar A. Boghdeh, Kenneth H. Risner, Michael D. Barrera, Clayton M. Britt, David K. Schaffer, Farhang Alem, Jacquelyn A. Brown, John P. Wikswo, Aarthi Narayanan   +8 more
doaj   +1 more source

Alphaviruses in Cancer Therapy

Frontiers in Molecular Biosciences, 2022
Alphaviruses have been engineered as expression vectors for different strategies of cancer therapy including immunotherapy and cancer vaccine development. Administration of recombinant virus particles, RNA replicons and plasmid DNA-based replicons provide great flexibility for alphavirus applications. Immunization and delivery studies have demonstrated
openaire   +3 more sources

The alphaviruses: gene expression, replication, and evolution [PDF]

, 1994
The alphaviruses are a genus of 26 enveloped viruses that cause disease in humans and domestic animals. Mosquitoes or other hematophagous arthropods serve as vectors for these viruses.
Strauss, Ellen G., Strauss, James H.
core  

Alphaviruses and their role in elucidating antiviral responses in mosquitoes

, 2016
The interaction between mosquito vectors and arthropod-borne viruses (arboviruses) such as alphaviruses of the Togaviridae family has long been of central interest to virologists.
Kohl, Alain, Melanie McFarlane, Alain Kohl, McFarlane, Melanie   +3 more
core   +1 more source

Antiviral drug discovery against arthritogenic alphaviruses: Tools and molecular targets

, 2020
Alphaviruses are (mainly) arthropod-borne viruses that belong to the family of the Togaviridae. Based on the disease they cause, alphaviruses are divided into an arthritogenic and an encephalitic group.
Abdelnabi, Rana, Neyts, Johan, Delang, Leen, Jacobs, Sofie   +3 more
core   +1 more source

Evidence of Differences in Cellular Regulation of Wolbachia-Mediated Viral Inhibition between Alphaviruses and Flaviviruses

Viruses
The intracellular bacterium Wolbachia is increasingly being utilised in control programs to limit the spread of arboviruses by Aedes mosquitoes. Achieving a better understanding of how Wolbachia strains can reduce viral replication/spread could be ...
Stephanie M. Rainey, Daniella A. Lefteri, Christie Darby, Alain Kohl, Andres Merits, Steven P. Sinkins   +5 more
doaj   +1 more source

Association Between Chikungunya Infection and Rheumatoid Arthritis in Taiwan—A Cross‐Sectional Study

International Journal of Rheumatic Diseases, Volume 29, Issue 8, August 2026.
ABSTRACT Objectives Chikungunya virus (CHIKV) infection might cause chronic chikungunya arthritis resembling rheumatoid arthritis (RA). The purpose of this study is to investigate the potential role of this virus in the pathogenesis of RA in Taiwan, a non‐endemic area. Methods This cross‐sectional study enrolled 98 RA patients and 200 healthy controls.
Chang‐Yi Yen, Chang‐Chi Lin, Ping‐Chang Lin, Ching‐Yi Tsai, Li‐Teh Liu, Chen‐Hsuan Lin, Chun‐Hong Chen, Chia‐Chun Tseng, Hua‐Chen Chan, Cheng‐Chin Wu, Tsan‐Teng Ou, Jih‐Jin Tsai, Jeng‐Hsien Yen   +12 more
wiley   +1 more source

Global emergence of Alphaviruses that cause arthritis in humans

, 2015
Arthropod-borne viruses (arboviruses) may cause severe emerging and re-emerging infectious diseases, which pose a significant threat to human and animal health in the world today.
Otieno, Viola, Mosomtai, Gladys, Ahlm, Clas,, Ahlm, Clas, Obanda, Vincent,, Evander, Magnus,, Bucht, Göran,, Otieno, Viola,, Evander, Magnus, Lwande, Olivia Wesula, Bucht, Göran, Obanda, Vincent, Lwande, Olivia Wesula,, Mosomtai, Gladys,   +13 more
core   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Spindle-E acts antivirally against alphaviruses in mosquito cells [PDF]

, 2018
Mosquitoes transmit several human- and animal-pathogenic alphaviruses (Togaviridae family). In alphavirus-infected mosquito cells two different types of virus-specific small RNAs are produced as part of the RNA interference response: short-interfering (
Sreenu, Vattipally B., Till, Bethan Eluned, Esther Schnettler, Dietrich, Isabelle, Varjak, Margus, Kohl, Alain, Schnettler, E, Sreenu, VB, Merits, A, Alain Kohl, Kohl, A, Bethan Eluned Till, Till, BE, Vattipally B. Sreenu, Isabelle Dietrich, Merits, Andres, Varjak, M, Schnettler, Esther, Dietrich, I, Margus Varjak, Andres Merits   +20 more
core   +1 more source