Results 11 to 20 of about 4,783,354 (355)
Brain Research Bulletin, 2023 Background: ANO1 is closely correlated with the activation of EGFR and CaMKII, while EGFR and CaMKII show low activation in amyotrophic lateral sclerosis (ALS) models.
Ying Wang +13 more
doaj +1 more source
Bromodomain inhibitors regulate the C9ORF72 locus in ALS [PDF]
Experimental Neurology, 2015 A hexanucleotide repeat expansion residing within the C9ORF72 gene represents the most common known cause of amyotrophic lateral sclerosis (ALS) and places the disease among a growing family of repeat expansion disorders. The presence of RNA foci, repeat-associated translation products, and sequestration of RNA binding proteins suggests that toxic RNA ...
Zane, Zeier +15 more
openaire +2 more sources
Histone deacetylase 2-mediated deacetylation of the Ribonuclease 1 promoter in inflamed human endothelial cells [PDF]
, 2020 Endothelial cells (ECs) function as protective barrier to separate the blood from the surrounding tissue by conducting crucial roles in regulation and maintenance of vascular homeostasis, such as control of vessel permeability or coagulation.
Bedenbender, Katrin
core +1 more source
DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress. [PDF]
, 2014 Loss-of-function mutations in DJ-1 (PARK7) gene account for about 1% of all familial Parkinson's disease (PD). While its physiological function(s) are not completely clear, DJ-1 protects neurons against oxidative stress in both in vitro and in vivo ...
Aleyasin, Hossein +15 more
core +11 more sources
Plant Protection Science, 2018 The chlorophyll fluorescence measurement to diagnose herbicide resistant Echinochloa species at the reproductive (late) growth stage was applied. The significant correlation between Fv/Fm (chlorophyll fluorescence measurements) and fresh weight (whole ...
Chuan-Jie Zhang, Do-Soon Kim
doaj +1 more source
Lessons from LIMK1 enzymology and their impact on inhibitor design [PDF]
, 2019 LIM domain kinase 1 (LIMK1) is a key regulator of actin dynamics. It is thereby a potential therapeutic target for the prevention of fragile X syndrome and amyotrophic lateral sclerosis.
Beltrami, A +10 more
core +2 more sources
First report of Vaccaria sp. from Iran exhibiting cross-resistance to acetolactate synthase inhibitors in wheat fields [PDF]
Journal of Advances in Plant ProtectionThe spread of weed resistance to herbicides threatens both Iranian and global agriculture. In 2019, a study was conducted to ascertain the resistance of Vaccaria spp. to conventional herbicides used in wheat fields.
Mohammad Roozkhosh +4 more
doaj +1 more source
Detecting herbicide-resistant Apera spica-venti with a chlorophyll fluorescence agar test
Plant, Soil and Environment, 2018 Reliable tests on herbicide resistance are important for resistance management. Despite well-established greenhouse bioassays, faster and in-season screening methods would aid in more efficient resistance detection.
Alexander Ingo LINN +3 more
doaj +1 more source
ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cells- derived motoneurons [PDF]
, 2015 Patient-derived induced Pluripotent Stem Cells (iPSCs) provide an opportunity to study human diseases mainly in those cases where no suitable model systems are available.
Bozzoni, Irene +9 more
core +4 more sources
Planta Daninha, 2019 : Chlorophyll fluorescence measurement is a precise research technique that can be used for studying the effect of herbicides with different modes of action on photosynthetic apparatus.
M. Kargar +3 more
semanticscholar +1 more source