Contribution of animal models to the mechanistic understanding of Alternative Pathway and Amplification Loop (AP/AL)-driven Complement-mediated Diseases. [PDF]
Immunol Rev, 2023 Gibson BG, Cox TE, Marchbank KJ.
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JAK/STAT: Why choose a classical or an alternative pathway when you can have both? [PDF]
J Cell Mol Med, 2022 Puigdevall L +3 more
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Therapeutic regulation of complement activation in extracorporeal circuits and intravascular treatments with special reference to the alternative pathway amplification loop. [PDF]
Immunol Rev, 2023 Ekdahl KN +6 more
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De-stabilizing innate immunity in COVID-19: effects of its own positive feedback and erratic viraemia on the alternative pathway of complement. [PDF]
R Soc Open SciReeve J.
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Distinct cross talk of IL-17 & TGF-β with the immature CD11c+ TRAF6(-/-) -null myeloid dendritic cell-derived osteoclast precursor (mDDOCp) may engage signaling toward an alternative pathway of osteoclastogenesis for arthritic bone loss in vivo. [PDF]
Immun Inflamm DisLiu YCG, Teng AY.
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The alternative pathway of complement
Springer Seminars in Immunopathology, 1984The alternative pathway of complement activation provides the host with a humoral component of the natural defense mechanisms against infectious agents. The six plasma proteins involved in recognition and activation perform a continuous surveillance function that does not require specific antibody to recognize potential pathogens.
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