Results 241 to 250 of about 1,609,187 (354)

Factor B, the complement alternative pathway serine proteinase, is a major constitutive protein synthesized and secreted by resident and elicited mouse macrophages.

, 1985
John S. Sundsmo, Jennie R. Chin, Ruth A. Papin, Daryl S. Fair, Zena Werb   +4 more
openalex   +1 more source

Alternative complement pathway-dependent ingestion of fluolite particles by human granulocytes. [PDF]

, 1981
M. Amin Arnaout, Francis W. Luscinskas, Fabian J. Lionetti, C A Alper, C. R. Valeri   +4 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Baicalin relieves complement alternative pathway activation-induced lung inflammation through inhibition of NF-κB pathway. [PDF]

BMC Complement Med Ther
Li J, Zhang QY, Lu QY, Liu QZ, Guo L, Li M, Sun QY.   +6 more
europepmc   +1 more source

Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19. [PDF]

Front Immunol, 2022
Niederreiter J, Eck C, Ries T, Hartmann A, Märkl B, Büttner-Herold M, Amann K, Daniel C.   +7 more
europepmc   +1 more source

Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway. [PDF]

, 1986
Michael S. Krangel
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Editorial: Community series in the role of complement in health and disease, volume II

Frontiers in Immunology
Maciej Cedzyński, Thomas Vorup-Jensen, Thomas Vorup-Jensen, Marcin Okrój, Anna S. Świerzko   +4 more
doaj   +1 more source

JAK/STAT: Why choose a classical or an alternative pathway when you can have both? [PDF]

J Cell Mol Med, 2022
Puigdevall L, Michiels C, Stewardson C, Dumoutier L.   +3 more
europepmc   +1 more source

The C3 convertase of the alternative pathway of human complement. Enzymic properties of the bimolecular proteinase [PDF]

, 1986
Michael K. Pangburn, Hans J. Müller‐Eberhard   +1 more
openalex   +1 more source