Results 241 to 250 of about 6,006,467 (356)

The third component of complement: covalent attachment of a radioactive sugar to the labile binding site of C3 via the alternative pathway. [PDF]

, 1981
Joseph L. Mann, Roberta O'Brien, Margaret K. Hostetter, Chester A. Alper, Fred S. Rosen, BM Babior   +5 more
openalex   +1 more source

An alternative pathway of imiquimod-induced psoriasis-like skin inflammation in the absence of interleukin-17 receptor a signaling.

Journal of Investigative Dermatology, 2013
K. El Malki, S. Karbach, Jula Huppert, M. Zayoud, S. Reissig, Rebecca Schüler, A. Nikolaev, K. Karram, T. Münzel, C. Kuhlmann, Heiko J. Luhmann, E. von Stebut, Simone Wörtge, F. Kurschus, A. Waisman   +14 more
semanticscholar   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

A Complement Atlas identifies interleukin 6 dependent alternative pathway dysregulation as a key druggable feature of COVID-19

, 2023
Van Damme KF, Hoste L, Declercq J, Leeuw ED, Maes B, Martens L, Colman R, Browaeys R, Bosteels C, Verwaerde S, Vermeulen N, Lameire S, Debeuf N, Deckers J, Stordeur P, Guilliams M, Schetters ST, Haerynck F, Tavernier SJ, Lambrecht BN.   +19 more
europepmc   +1 more source

JAK/STAT: Why choose a classical or an alternative pathway when you can have both? [PDF]

J Cell Mol Med, 2022
Puigdevall L, Michiels C, Stewardson C, Dumoutier L.   +3 more
europepmc   +1 more source

Activation of the Alternative Complement Pathway by Blood Culture Isolates of Bacteroides fragilis [PDF]

, 1981
Keith A. Joiner, Alexandra Hawiger, Jeffrey A. Gelfand   +2 more
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Editorial: The Role of Complement in Health and Disease

Frontiers in Immunology, 2019
Maciej Cedzyński, Nicole M. Thielens, Tom Eirik Mollnes, Tom Eirik Mollnes, Tom Eirik Mollnes, Thomas Vorup-Jensen, Thomas Vorup-Jensen   +6 more
doaj   +1 more source

Therapeutic regulation of complement activation in extracorporeal circuits and intravascular treatments with special reference to the alternative pathway amplification loop. [PDF]

Immunol Rev, 2023
Ekdahl KN, Fromell K, Mannes M, Grinnemo KH, Huber-Lang M, Teramura Y, Nilsson B.   +6 more
europepmc   +1 more source

Alternative complement pathway-dependent ingestion of fluolite particles by human granulocytes. [PDF]

, 1981
M. Amin Arnaout, Francis W. Luscinskas, Fabian J. Lionetti, C A Alper, C. R. Valeri   +4 more
openalex   +1 more source