Results 251 to 260 of about 1,689,260 (355)

Is the Brain an Activator of the Alternative Cellular Energy (ACE) Pathway? [PDF]

, 2015
John Martin
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Baicalin relieves complement alternative pathway activation-induced lung inflammation through inhibition of NF-κB pathway. [PDF]

BMC Complement Med Ther
Li J, Zhang QY, Lu QY, Liu QZ, Guo L, Li M, Sun QY.   +6 more
europepmc   +1 more source

Maternal and Fetal Alternative Complement Pathway Activation in Early Severe Preeclampsia

, 2013
M. Camille Hoffman, Kristen K. Rumer, Anita Kramer, Anne M. Lynch, Virginia D. Winn   +4 more
openalex   +2 more sources

An alternative pathway for bone destruction in inflammatory arthritis? [PDF]

, 2012
Katrina Ray
openalex   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Reconstitution of the alternative pathway of the complement system enables rapid delineation of the mechanism of action of novel inhibitors. [PDF]

J Biol Chem
Goodrich AC, LeClair NP, Shillova N, Morton WD, Wittwer AJ, Loyet KM, Hannoush RN.   +6 more
europepmc   +1 more source

Determination of optimal in vitro conditions for camel alternative complement pathway assay

, 2001
V. Chopra, Sonu Kashyap
openalex   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Alternative cost-optimal pathways for the transport sector of Cyprus

, 2015
Josefin Wiking
openalex   +1 more source