Alternative pathway activation in pregnancy, a measured amount "complements" a successful pregnancy, too much results in adverse events. [PDF]
Smith-Jackson K, Harrison RA.
europepmc +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Suppression of endometriosis by miRNA-34a via inhibition of matrix metalloproteinase-2: An alternative pathway to impede invasion. [PDF]
Begum Y +6 more
europepmc +1 more source
Bone Marrow Derived Cells and Alternative Pathways of Oogenesis in Adult Rodents [PDF]
Antonín Bukovský +4 more
openalex +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Complement classical and alternative pathway activation contributes to diabetic kidney disease progression: a glomerular proteomics on kidney biopsies. [PDF]
Yang Y +13 more
europepmc +1 more source
Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19. [PDF]
Niederreiter J +7 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation. [PDF]
Gerogianni A +11 more
europepmc +1 more source

