Results 51 to 60 of about 9,049 (204)
α-amanitin induces hepatotoxicity via PPAR-γ inhibition and NLRP3 inflammasome activation
Ecotoxicology and Environmental SafetyMushroom poisoning, predominantly caused by α-amanitin, is a critical food safety concern in worldwide, with severe cases leading to hepatotoxicity and fatalities.
Haowei Wang +9 more
doaj +1 more source
Transposable elements: Functional aspects and applications as drivers of crop innovation
Crop Science, Volume 66, Issue 2, March/April 2026.Abstract Transposable elements (TEs), which were once relegated to the status of genomic parasites, are today accepted as important agents of plant genome evolution and adaptation. This review integrates evidence pointing to their dual function as drivers of genetic diversity and instability, with a focus on their contribution to phenotypic innovation,
Flávia Layse Belém Medeiros +12 more
wiley +1 more source
Toxins, 2018 One of the deadliest mushrooms is the death cap mushroom, Amanita phalloides. The most toxic constituent is α-amanitin, a bicyclic octapeptide, which damages the liver and kidneys.
Candace S. Bever +4 more
doaj +1 more source
The occurrence of ansamers in the synthesis of cyclic peptides
Nature Communications, 2022 The occurrence of isomers of the bicyclic octapeptide α-amanitin, which presents a macrolactam with a tryptathionine cross-link forming a handle, has been reported under the term of atropoisomers.
Guiyang Yao +6 more
doaj +1 more source
PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana +4 more
wiley +1 more source
Frontiers in Microbiology, 2020 Many species of Amanita sect. Phalloideae (Fr.) Quél. cause death of people after consumption around the world. Amanita albolimbata, a new species of A. sect. Phalloideae from Benin, is described here.
Jean Evans I. Codjia +8 more
doaj +1 more source
Amanitine poisoning - cases, management, therapy results
Journal of Education, Health and Sport, 2023 Mushroom poisoning continues to be a serious clinical problem. The most serious are intoxications with mushrooms containing cytotropic toxins with predominant injury of liver, kidneys and heart. The toxic properties of the phalloides are mainly due to α-
Magdalena Kubicka +5 more
doaj +1 more source
Genes to Cells, Volume 31, Issue 2, March 2026.In the giant Pleurodeles waltl genome, introns serve as “structural buffers,” absorbing transposable elements (TEs) to protect coding exons. While this enables “gene body inflation,” persistent TE accumulation eventually leads to transcriptional silencing and functional collapse, or “burst,” of the gene architecture.
Kazuto Bou, Kiyokazu Agata
wiley +1 more source
Investigating the phylogenetic history of toxin tolerance in mushroom‐feeding Drosophila
Ecology and Evolution, 2023 Understanding how and when key novel adaptations evolved is a central goal of evolutionary biology. Within the immigrans‐tripunctata radiation of Drosophila, many mushroom‐feeding species are tolerant of host toxins, such as cyclopeptides, that are ...
Theresa Erlenbach +7 more
doaj +1 more source
ChemBioChem, Volume 26, Issue 24, December 11, 2025.An isolable cysteine sulfenyl iodide (Cys–SI) stabilized by a molecular cradle is reported. X‐ray analysis and reactivity studies reveal hydrolysis to sulfenic acid, electrophilic substitution with indoles, and high reactivity toward amines and dimedone, providing direct evidence for long‐standing proposals on iodine‐mediated protein modification ...
Shotaro Otaka +4 more
wiley +1 more source