Results 31 to 40 of about 9,049 (204)

An investigation of a food poisoning by Galerina sulciceps

open access: yesZhongguo shipin weisheng zazhi, 2020
Objective To investigate a food poisoning caused by wild mushrooms and to identify the risk factors. Methods Epidemiological investigation, morphological and phylogenetic identification, and laboratory testing were taken to analyze the poisoning event ...
Zhifan HE   +7 more
doaj   +1 more source

Calculating RNA degradation rates using large-scale normalization in mouse embryonic stem cells

open access: yesSTAR Protocols, 2023
Summary: Data normalization is critical to the process of estimating RNA degradation by analyzing RNA levels when transcription is blocked. Here, we present a protocol for measuring mRNA degradation rates, optimized for mouse embryonic stem cells, using ...
Juliane Oliveira Viegas   +3 more
doaj   +1 more source

Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass Spectrometry

open access: yesToxins, 2020
Amatoxins are known to be one of the main causes of serious to fatal mushroom intoxication. Thorough treatment, analytical confirmation, or exclusion of amatoxin intake is crucial in the case of any suspected mushroom poisoning.
Thomas P. Bambauer   +3 more
doaj   +1 more source

Cyclosporine as a novel treatment for amatoxin-containing mushroom poisoning: a case series

open access: yesToxicology Communications, 2022
Ingestion of amatoxin-containing mushrooms can lead to fulminant hepatotoxicity and death. Despite recent interest in therapeutic options for amatoxin-exposed patients, there is no single, recommended treatment for amatoxin poisoning. Alpha-amanitin, the
Constance A. Mackenzie   +3 more
doaj   +1 more source

MiR-1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion. [PDF]

open access: yesEnviron Toxicol
ABSTRACT MicroRNA‐1 (miR‐1) is a conserved microRNA that is highly expressed in skeletal and cardiac muscle tissues. Moreover, miR‐1 regulates genes and has critical roles in cell migration and invasion. Downregulation of miR‐1 has been found in many pathologies of numerous organs, including the lungs.
Pacurari M, Cox I, Farah I.
europepmc   +2 more sources

Investigation of a mushroom poisoning incident caused by Amanita fuliginea in Guizhou Province

open access: yesZhongguo shipin weisheng zazhi, 2023
ObjectiveTo provide support and reference for the diagnosis, investigation, laboratory testing, and prevention of toxic mushroom poisoning in Guizhou, an Amanita fuliginea poisoning incident in Bijie, Guizhou Province was investigated.MethodsAn ...
ZHU Shu   +4 more
doaj   +1 more source

A Sensitive, Cell-Based Assay for Measuring Low-Level Biological Activity of α-Amanitin

open access: yes, 2023
α-Amanitin is one of the primary toxins produced by the poisonous mushroom genus, Amanita. Because it is odorless and tasteless, it is an important cause of death from the consumption of misidentified mushrooms.
Xiaohua He   +3 more
core   +1 more source

Affinity isolation of RNA polymerase II on amanitin-Sepharose [PDF]

open access: yes, 1984
We report here the first case of an affinity isolation of eukaryotic RNA polymerase II. The procedure employs an affinity matrix composed of [alpha]-amanitin coupled to Sepharose 4B via a ten atom spacer.
Faulstich, H.   +3 more
core   +1 more source

Synthesis of the Death-Cap Mushroom Toxin α‑Amanitin

open access: yes, 2018
α-Amanitin is an extremely toxic bicyclic octapeptide isolated from the death-cap mushroom, Amanita phalloides. As a potent inhibitor of RNA polymerase II, α-amanitin is toxic to eukaryotic cells.
Kaveh Matinkhoo (4990370)   +4 more
core   +2 more sources

Detection and analysis of amatoxins in 3 species of Lepiota from Chuxiong, Yunnan Province

open access: yesZhongguo shipin weisheng zazhi
ObjectiveTo analyze the content of 6 kinds of amatoxins in 3 species of Lepiota collected from Chuxiong of Yunnan Province.MethodsThe collected mushrooms were baked and dried at 45 ℃, and species identification was carried out by morphological and ...
XU Ping   +6 more
doaj   +1 more source

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