Results 41 to 50 of about 9,049 (204)
, 2013 LB cells were treated for 24h with α–amanitin with or without DFO treatment. (A) Relative quantification of mRNA. mRNA was quantified relatively to the non-treated sample which was set as 1.
Ninette Amariglio (10560) +3 more
core +1 more source
Effects of thymoquinone on alpha-amanitin induced hepatotoxicity in human C3A hepatocytes
, 2022 Thymoquinone (TQ) has shown hepatoprotective effects in various experimental studies. We aimed to investigate the possible beneficial effects of TQ regarding its prevention of alpha-amanitin induced hepatotoxicity in human C3A hepatocytes.
Kaya, Ertuğrul +8 more
core +2 more sources
The Role of Ferroptosis in Hepatocyte Injury Induced by α-Amanitin
Fayixue ZazhiObjectiveTo explore whether ferroptosis is involved in α-amanitin-induced hepatocyte injury by detecting iron deposition in mice liver tissues, oxidative stress indicators in hepatocytes and L-02 cells, and expressions of ferroptosis-related proteins ...
WANG Hao-wei +4 more
doaj +1 more source
Clinical Toxicology, 2022 BACKGROUND AND AIMS: Amanita phalloides poisoning causes severe liver damage which may be potentially fatal. Several treatments are available, but their effectiveness has not been systematically evaluated. We performed a systematic review to investigate the effect of the most commonly used therapies: N-acetylcysteine (NAC), benzylpenicillin (PEN), and ...
Tan, Jia Lin +5 more
openaire +1 more source
Zhongguo shipin weisheng zazhi, 2022 ObjectiveTo establish an analytical method for 9 mushroom toxins in wild fungus by liquid chromatography-tandem mass spectrometry （LC-MS/MS） including 5 acute liver failure toxins （α-amanitin， β-amanitin， γ-amanitin， phallacidin and phalloidin） and 4 ...
XU Xiaomin +5 more
doaj +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde +4 more
wiley +1 more source
Prolonged α-amanitin treatment of cells for studying mutated polymerases causes degradation of DSIF 160 and other proteins [PDF]
, 2012 A useful method for studying the function of the mammalian RNA polymerase II takes advantage of the extreme sensitivity of its largest subunit, Rpb1, to alpha-amanitin (a-amanitin).
Tsao, David Ching-heng
core +2 more sources
Predator–Microbe Dynamics Inform Strategies for Robust Synthetic Community Assembly
Environmental Microbiology, Volume 28, Issue 6, June 2026.This Review introduces ecological principles of predator–prey interactions as a new dimension in SynCom design. By linking microbial defence traits, encounter dynamics, and adaptive buffering, it outlines a framework for constructing predator‐resistant synthetic communities with enhanced resilience, stability, and functional performance under natural ...
Eleonora Egidi, Uffe N. Nielsen
wiley +1 more source
The mechanisms underlying α-amanitin resistance in Drosophila melanogaster: a microarray analysis.
PLoS ONE, 2014 The rapid evolution of toxin resistance in animals has important consequences for the ecology of species and our economy. Pesticide resistance in insects has been a subject of intensive study; however, very little is known about how Drosophila species ...
Chelsea L Mitchell +4 more
doaj +1 more source
In vivo and in vitro α-amanitin metabolism studies using molecular networking
, 2021 International audienceAmanitin poisonings are among the most life-threatening mushroom poisonings, and are mainly caused by the genus Amanita. Hepatotoxicity is the hallmark of amanitins, powerful toxins contained in these mushrooms, and can require ...
Gicquel, Thomas +5 more
core +1 more source