Results 61 to 70 of about 8,493 (176)

Relationship Between the Conformation of the Cyclopeptides Isolated from the Fungus Amanita Phalloides (Vaill. Ex Fr.) Secr. and Its Toxicity

Molecules, 2000
The electronic structures and conformational studies of the cyclopeptides, Omethyl-α-amanitin, phalloidin and antamanide, were obtained from molecular parameters on the basis of semiempiric and ab initio methods.
M. E. Battista, A. A. Vitale, A. B. Pomilio   +2 more
doaj   +1 more source

Isolable Cysteine Sulfenyl Iodide: Stabilization by a Molecular Cradle, Crystal Structure, and Biologically Relevant Reactivity

ChemBioChem, Volume 26, Issue 24, December 11, 2025.
An isolable cysteine sulfenyl iodide (Cys–SI) stabilized by a molecular cradle is reported. X‐ray analysis and reactivity studies reveal hydrolysis to sulfenic acid, electrophilic substitution with indoles, and high reactivity toward amines and dimedone, providing direct evidence for long‐standing proposals on iodine‐mediated protein modification ...
Shotaro Otaka, Tsukasa Sano, Shohei Sase, Satoru Kuwano, Kei Goto   +4 more
wiley   +1 more source

A Simple and High-Throughput Analysis of Amatoxins and Phallotoxins in Human Plasma, Serum and Urine Using UPLC-MS/MS Combined with PRiME HLB μElution Platform

Toxins, 2016
Amatoxins and phallotoxins are toxic cyclopeptides found in the genus Amanita and are among the predominant causes of fatal food poisoning in China.
Shuo Zhang, Yunfeng Zhao, Haijiao Li, Shuang Zhou, Dawei Chen, Yizhe Zhang, Qunmei Yao, Chengye Sun   +7 more
doaj   +1 more source

Determination of Amatoxins in Lepiota brunneoincarnata and Lepiota venenata by High-Performance Liquid Chromatography Coupled with Mass Spectrometry

Mycobiology, 2020
Three hepatic failure poisoning incidents caused by Lepiota brunneoincarnata and Lepiota venenata mushrooms have been occurred in China in 2017, L. venenata has been described as a new species.
Pan Long, Fengxia Fan, Bin Xu, Zhengmi He, Yuting Su, Ping Zhang, Jianwei Xie, Zuohong Chen   +7 more
doaj   +1 more source

Simultaneous Determination of Multi-Class Mushroom Toxins in Mushroom and Biological Liquid Samples Using LC-MS/MS

Separations
A comprehensive analytical method based on liquid chromatography–tandem mass spectrometry (LC-MS/MS) was developed for the simultaneous detection of 12 mushroom toxins (ibotenic acid, muscimol, muscarine, β-amanitin, α-amanitin, desoxoviroidin, γ ...
Junjia Lu, Jing Zhang, Haijiao Li, Chengye Sun   +3 more
doaj   +1 more source

Quantifying disease severity in amanitin-intoxicated patients by fusing common laboratory values

Frontiers in Toxicology
IntroductionAmanitin intoxication following ingestion of amatoxin-containing mushrooms can cause acute hepatic and renal failure. We evaluated the feasibility of using an adapted Patient Vital Status (PVS) fusion score derived from routine laboratory ...
Philipp L. S. Ohland, Stephan Halle, Stephan Halle, Korbinian Brand, André Bleich, Steven R. Talbot, Steven R. Talbot   +6 more
doaj   +1 more source

Study of three interesting Amanita species from Thailand: Morphology, multiple-gene phylogeny and toxin analysis.

PLoS ONE, 2017
Amanita ballerina and A. brunneitoxicaria spp. nov. are introduced from Thailand. Amanita fuligineoides is also reported for the first time from Thailand, increasing the known distribution of this taxon.
Benjarong Thongbai, Steven L Miller, Marc Stadler, Kathrin Wittstein, Kevin D Hyde, Saisamorn Lumyong, Olivier Raspé   +6 more
doaj   +1 more source

Application of single-pass albumin dialysis in the acute phase of amanitin syndrome caused by mushroom poisoning [PDF]

Vojnosanitetski Pregled
Introduction. The frequency of mushroom poisoning is increasing both in the world and in our country. The most poisonous type of mushroom in our region is Amanita phalloides, which causes amanitin syndrome in poisoned patients, and it is considered ...
Jovanović Dragana, Pilčević Dejan, Isailović Jelena, Vukčević Perković Nataša, Vuković Rade   +4 more
doaj   +1 more source

Single cell analysis of transcriptional activation dynamics.

PLoS ONE, 2010
BackgroundGene activation is thought to occur through a series of temporally defined regulatory steps. However, this process has not been completely evaluated in single living mammalian cells.Methodology/principal findingsTo investigate the timing and ...
Ilona U Rafalska-Metcalf, Sara Lawrence Powers, Lucy M Joo, Gary LeRoy, Susan M Janicki   +4 more
doaj   +1 more source

Rapid analysis of amatoxins in human urine by means of affinity column chromatography and liquid chromatography-high-resolution tandem mass spectrometry

Scientific Reports
Analysis of amatoxins is of great importance as these cyclic peptides contribute to a high number of fatalities each year. Development of analytical approaches needs to focus on rapid, sensitive, and reliable methods.
Aline C. Vollmer, Claudia Fecher-Trost, Candace S. Bever, Christina C. Tam, Lea Wagmann, Markus R. Meyer   +5 more
doaj   +1 more source