Results 21 to 30 of about 8,493 (176)

Profiling of Amatoxins and Phallotoxins in the Genus Lepiota by Liquid Chromatography Combined with UV Absorbance and Mass Spectrometry

Toxins, 2014
Species in the mushroom genus Lepiota can cause fatal mushroom poisonings due to their content of amatoxins such as α-amanitin. Previous studies of the toxin composition of poisonous Lepiota species relied on analytical methods of low sensitivity or ...
R. Michael Sgambelluri, Sara Epis, Davide Sassera, Hong Luo, Evan R. Angelos, Jonathan D. Walton   +5 more
doaj   +1 more source

Convergence and parallelism in the evolution of plant metabolism. [PDF]

J Integr Plant Biol
Similar traits in different organisms may originate from shared ancestry or evolve independently. The terminology used to define phenotypic similarity is often confusing. This review attempts to clarify the definitions and present examples from plant domestication and specialized metabolism to explain how complex traits evolve repeatedly in plants ...
Scossa F, Bulut M, Naake T, D'Auria JC, Fernie AR.   +4 more
europepmc   +2 more sources

Establishment of Indirect Competitive ELISA Method for Detecting Amanitin in Mushroom

Shipin gongye ke-ji, 2022
Objective: This study aims to establish an indirect competitive enzyme-linked immunosorbent assay for the detection of amanitin (AMA) in mushroom. Methods: In this study, the hapten was obtained by introducing 6-aminocaproic acid into the carboxyl ...
Hebing LIU, Yu QIN, Weiwei XING, Licai MA   +3 more
doaj   +1 more source

Diversity of MSDIN family members in amanitin-producing mushrooms and the phylogeny of the MSDIN and prolyl oligopeptidase genes

BMC Genomics, 2020
Background Amanitin-producing mushrooms, mainly distributed in the genera Amanita, Galerina and Lepiota, possess MSDIN gene family for the biosynthesis of many cyclopeptides catalysed by prolyl oligopeptidase (POP). Recently, transcriptome sequencing has
Zhengmi He, Pan Long, Fang Fang, Sainan Li, Ping Zhang, Zuohong Chen   +5 more
doaj   +1 more source

An investigation of a food poisoning by Galerina sulciceps

Zhongguo shipin weisheng zazhi, 2020
Objective To investigate a food poisoning caused by wild mushrooms and to identify the risk factors. Methods Epidemiological investigation, morphological and phylogenetic identification, and laboratory testing were taken to analyze the poisoning event ...
Zhifan HE, Haiying MA, Qiang ZHANG, Chunying LUO, Min FENG, Xixi WANG, Yao WANG, Xiaohui LI   +7 more
doaj   +1 more source

Hypoadrenocorticism in a Dog Following Recovery from Alpha-Amanitin Intoxication

Veterinary Sciences, 2023
A 10-year-old, female spayed Labrador Retriever was referred for acute hepatopathy and urinary retention. Blood work from the initial presentation (day 0) revealed a severe, mixed hepatopathy. Over the course of the patient’s hospitalization, the patient
Emily A. Cohen, Courtney M. Moeller, Jonathan D. Dear   +2 more
doaj   +1 more source

Calculating RNA degradation rates using large-scale normalization in mouse embryonic stem cells

STAR Protocols, 2023
Summary: Data normalization is critical to the process of estimating RNA degradation by analyzing RNA levels when transcription is blocked. Here, we present a protocol for measuring mRNA degradation rates, optimized for mouse embryonic stem cells, using ...
Juliane Oliveira Viegas, Lior Fishman, Eran Meshorer, Michal Rabani   +3 more
doaj   +1 more source

Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass Spectrometry

Toxins, 2020
Amatoxins are known to be one of the main causes of serious to fatal mushroom intoxication. Thorough treatment, analytical confirmation, or exclusion of amatoxin intake is crucial in the case of any suspected mushroom poisoning.
Thomas P. Bambauer, Lea Wagmann, Armin A. Weber, Markus R. Meyer   +3 more
doaj   +1 more source

Unraveling Hematotoxicity of α-Amanitin in Cultured Hematopoietic Cells

Toxins
Amanita phalloides poisonings account for the majority of fatal mushroom poisonings. Recently, we identified hematotoxicity as a relevant aspect of Amanita poisonings. In this study, we investigated the effects of the main toxins of Amanita phalloides, α-
Willemien F. J. Hof, Miranda Visser, Joyce J. de Jong, Marian N. Rajasekar, Jan Jacob Schuringa, Inge A. M. de Graaf, Daan J. Touw, Bart G. J. Dekkers   +7 more
doaj   +1 more source

Cyclosporine as a novel treatment for amatoxin-containing mushroom poisoning: a case series

Toxicology Communications, 2022
Ingestion of amatoxin-containing mushrooms can lead to fulminant hepatotoxicity and death. Despite recent interest in therapeutic options for amatoxin-exposed patients, there is no single, recommended treatment for amatoxin poisoning. Alpha-amanitin, the
Constance A. Mackenzie, Emily Austin, Margaret Thompson, Rommel G. Tirona   +3 more
doaj   +1 more source