Results 121 to 130 of about 12,409 (229)

Probing the enzymatic activity and maturation process of the EcAIII Ntn-amidohydrolase using local random mutagenesis

Acta Biochimica Polonica
This report describes a comprehensive approach to local random mutagenesis of the E. coli Ntn-amidohydrolase EcAIII, and supplements the results published earlier for the randomization series RDM1.
Joanna I. Loch, Anna Ściuk, Anna Ściuk, Marta Kilichowska, Marta Kilichowska, Izabela Pieróg, Izabela Pieróg, Weronika Łukaszczyk, Katarzyna Zimowska, Mariusz Jaskolski, Mariusz Jaskolski   +10 more
doaj   +1 more source

Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen [PDF]

, 2001
Sandra Holt, Jonas Nilsson, Romelda Omeir, Gunnar Tiger, Christopher J. Fowler   +4 more
openalex   +1 more source

Prospecting for Unannotated Enzymes: Discovery of a 3′,5′-Nucleotide Bisphosphate Phosphatase within the Amidohydrolase Superfamily

Biochemistry, 2014
In bacteria, 3′,5′-adenosine bisphosphate (pAp) is generated from 3′-phosphoadenosine 5′-phosphosulfate in the sulfate assimilation pathway, and from coenzyme A by the transfer of the phosphopantetheine group to the acyl-carrier protein.
J. Cummings, M. Vetting, Swapnil V Ghodge, Chengfu Xu, B. Hillerich, R. Seidel, S. Almo, F. Raushel   +7 more
semanticscholar   +1 more source

Structural Basis for pH-Dependent Oligomerization of Dihydropyrimidinase from Pseudomonas aeruginosa PAO1

Bioinorganic Chemistry and Applications, 2018
Dihydropyrimidinase, a dimetalloenzyme containing a carboxylated lysine within the active site, is a member of the cyclic amidohydrolase family, which also includes allantoinase, dihydroorotase, hydantoinase, and imidase.
Jen-Hao Cheng, Chien-Chih Huang, Yen-Hua Huang, Cheng-Yang Huang   +3 more
doaj   +1 more source

ASAH1 facilitates TNBC by DUSP5 suppression-driven activation of MAP kinase pathway and represents a therapeutic vulnerability

Cell Death and Disease
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is prone to metastasis and therapy resistance. Owing to its aggressive nature and limited availability of targeted therapies, TNBC is associated with higher mortality as compared to ...
Kiran Kumar Reddi, Suresh Chava, Siva Chander Chabattula, Yvonne J. K. Edwards, Kamaljeet Singh, Romi Gupta   +5 more
doaj   +1 more source

A New Strategy to Inhibit Scar Formation by Accelerating Normal Healing Using Silicate Bioactive Materials

Advanced Science
Inspired by the scar‐free wound healing in infants, an anti‐scar strategy is proposed by accelerating wound healing using silicate bioactive materials.
Zhaowenbin Zhang, Chen Fan, Qing Xu, Feng Guo, Wenbo Li, Zhen Zeng, Yuze Xu, Jing Yu, Hongping Ge, Chen Yang, Jiang Chang   +10 more
doaj   +1 more source

Identification, Biochemical Characterization, and Subcellular Localization of Allantoate Amidohydrolases from Arabidopsis and Soybean [PDF]

, 2007
Andrea K. Werner, Imogen Sparkes, Tina Romeis, Claus‐Peter Witte   +3 more
openalex   +1 more source

Exploring the Effect and Molecular Docking Interaction of Carboxypeptidase and Amidohydrolase on Ochratoxin A and Zearalenone Degradation

BioResources
To keep consumers from the hazard of exposure to mycotoxins and meet the allowed limits, numerous physical and chemical approaches for eliminating Ochratoxin A (OTA) and Zearalenone (ZEN) have been studied.
Sulaiman A. Alsalamah, Mohammed Ibrahim Alghonaim, Abdu Ali Y. Moafa, Mukul Sharma   +3 more
doaj  

Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies [PDF]

, 2009
Ursula Pieper, Ranyee A. Chiang, Jennifer J. Seffernick, Shoshana Brown, Margaret E. Glasner, Libusha Kelly, Narayanan Eswar, J.M. Sauder, J.B. Bonanno, Subramanyam Swaminathan, S.K. Burley, Xiaojing Zheng, Mark R. Chance, Steven C. Almo, J.A. Gerlt, Frank M. Raushel, Matthew P. Jacobson, Patricia C. Babbitt, Andrej Săli   +18 more
openalex   +1 more source

Phenoxymethylpenicillin amidohydrolases from Penicillium chrysogenum [PDF]

, 1996
Pat Whiteman, E. P. Abraham
openalex   +1 more source