Results 31 to 40 of about 170,643 (213)

Glucose-Potentiated Amikacin Killing of Cefoperazone/Sulbactam Resistant Pseudomonas aeruginosa

Frontiers in Microbiology, 2022
Multidrug-resistant Pseudomonas aeruginosa has become one of global threat pathogens for human health due to insensitivity to antibiotics. Recently developed reprogramming metabolomics can identify biomarkers, and then, the biomarkers were used to revert
Xi-kang Tang, Xi-kang Tang, Yu-bin Su, Hui-qing Ye, Hui-qing Ye, Zhen-yuan Dai, Zhen-yuan Dai, Huan Yi, Huan Yi, Ke-xin Yang, Ke-xin Yang, Tian-tuo Zhang, Zhuang-gui Chen, Zhuang-gui Chen   +13 more
doaj   +1 more source

Antibiotic Sensitivity Testing and Molecular Characteristics Related to Clarithromycin and Amikacin Resistance in Mycobacterium abscessus Complex Isolated from Patients with Pulmonary Infection at National Hospital 74, Vietnam

International Journal of Mycobacteriology
Background: Mycobacterium abscessus complex (MABC) is an important cause of opportunistic infections in the respiratory tracts. Data on antimicrobial resistance of MABC in Vietnam were still lacking. Methods: From December 2021 to July 2022, mycobacteria
Vu Thi Thuong, Bui Thi Thanh Nga, Le Thi Lan Anh, Nguyen Van Doai, Nguyen Minh Phuong, Luu Van Doan, Pham Viet Hung   +6 more
doaj   +1 more source

Nocardia transvalensis keratitis: an emerging pathology among travelers returning from Asia

BMC Infectious Diseases, 2011
Background The incidence rate of Nocardia keratitis is increasing, with new species identified thanks to molecular methods. We herein report a case of Nocardia transvalensis keratitis, illustrating this emerging pathology among travellers returning from ...
Trichet Elodie, Cohen-Bacrie Stéphan, Conrath John, Drancourt Michel, Hoffart Louis   +4 more
doaj   +1 more source

Incidence of Acute Kidney Injury in Autologous Hematopoietic Stem Cell Transplant Recipients According to the Administration of Empirical Amikacin: A Two-Centre Retrospective Cohort Study

Antibiotics
Background: The benefit of adjunctive aminoglycosides in the treatment of patients with febrile neutropenia (FN) is controversial. We investigated the incidence of acute kidney injury (AKI) in patients with FN or suspected infection according to ...
Sophie Schürch, Sarah Dräger, Michèle Hoffmann, Severin Bausch, Nicolas Gürtler, Cédric Hirzel, Jakob Passweg, Stefano Bassetti, Thomas Pabst, Parham Sendi, Michael Osthoff   +10 more
doaj   +1 more source

Exposure of Mycobacterium abscessus to Environmental Stress and Clinically Used Antibiotics Reveals Common Proteome Response among Pathogenic Mycobacteria

Microorganisms, 2020
Mycobacterium abscessus subsp. abscessus (MAB) is a clinically important nontuberculous mycobacterium (NTM) causing pulmonary infection in patients such as cystic fibrosis and bronchiectasis.
Rajoana Rojony, Lia Danelishvili, Anaamika Campeau, Jacob M. Wozniak, David J. Gonzalez, Luiz E. Bermudez   +5 more
doaj   +1 more source

Amikacin Liposome Inhalation Suspension (ALIS) Penetrates Non-tuberculous Mycobacterial Biofilms and Enhances Amikacin Uptake Into Macrophages

Frontiers in Microbiology, 2018
Non-tuberculous mycobacteria (NTM) cause pulmonary infections in patients with structural lung damage, impaired immunity, or other risk factors. Delivering antibiotics to the sites of these infections is a major hurdle of therapy because pulmonary NTM ...
Jimin Zhang, F. Leifer, S. Rose, D. Y. Chun, Jill Thaisz, Tracey Herr, M. Nashed, J. Joseph, W. Perkins, K. Dipetrillo   +9 more
semanticscholar   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Perbandingan Efektivitas Kombinasi Ceftazidime + Amikasin dan Ceftazidime sebagai Antibiotik Empiris Demam Neutropenia pada Keganasan

Sari Pediatri, 2016
Latar belakang. Terapi antibiotik empiris spektrum luas merupakan standar pengobatan demam neutropenia pada keganasan karena morbiditas dan mortalitas yang berhubungan dengan sepsis bakterial.
Agustinus William, Rini Purnamasari, Yulia Iriani, Theodorus Theodorus   +3 more
doaj   +1 more source

Effect of Imipenem and Amikacin Combination against Multi-Drug Resistant Pseudomonas aeruginosa

Antibiotics, 2021
Pseudomonas aeruginosa is an opportunistic nosocomial pathogen associated with high morbidity and mortality rates. Combination of antibiotics has been found to combat multi-drug resistant or extensively drug resistance P. aeruginosa.
Sara Mahmoud Farhan, Mohamed Raafat, Mohammed A. S. Abourehab, Rehab Mahmoud Abd El-Baky, Salah Abdalla, Ahmed Osama EL-Gendy, Ahmed Farag Azmy   +6 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source