Results 211 to 220 of about 15,918,440 (250)

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

open access: yesInternational Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg   +4 more
wiley   +1 more source

A Novel SXXLF Motif in the FXR N‐Terminal Domain Mediates Coregulator and Interdomain Interactions

open access: yesChemBioChem, Volume 27, Issue 17, 14 September 2026.
Farnesoid X receptor (FXR)‐N‐terminal domain (NTD) regulates transcriptional activity through interdomain communication with the LBD and is also involved in co‐activator recruitment. The SENLF motif is the first defined functional element within the FXR‐NTD and mediates both NTD–LBD interaction and selective co‐activator engagements to drive NTD ...
Priscilla Villalona   +8 more
wiley   +1 more source

Sodium Channel Blockers Demonstrate Binding Affinity for the Tandem Tudor Domain of the Epigenetic Hub UHRF1

open access: yesChemMedChem, Volume 21, Issue 17, 14 September 2026.
An investigation of the tandem Tudor domain (TTD) domain of UHRF1 identified and extensively characterized the local anesthetic hydroxyprocaine as a strong ligand capable of activating related genes such as p53 and also highlighted a new, potentially druggable intramolecular interaction between TTD and UBL.
Efstratios Tsakalidis   +16 more
wiley   +1 more source

Enzymological studies of D-amino acid N-acetyltransferase from Saccharomyces cerevisiae

open access: yesEnzymological studies of D-amino acid N-acetyltransferase from Saccharomyces cerevisiae
openaire   +1 more source

NAT10: a potential factor to reverse tumor chemotherapy resistance and radioresistance (Review). [PDF]

open access: yesFront Immunol
Li S   +8 more
europepmc   +1 more source

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