ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg +4 more
wiley +1 more source
Laboratory evolution drives continued genome degradation in the facultative tsetse symbiont Sodalis glossinidius. [PDF]
Pescod P +3 more
europepmc +1 more source
A Novel SXXLF Motif in the FXR N‐Terminal Domain Mediates Coregulator and Interdomain Interactions
Farnesoid X receptor (FXR)‐N‐terminal domain (NTD) regulates transcriptional activity through interdomain communication with the LBD and is also involved in co‐activator recruitment. The SENLF motif is the first defined functional element within the FXR‐NTD and mediates both NTD–LBD interaction and selective co‐activator engagements to drive NTD ...
Priscilla Villalona +8 more
wiley +1 more source
Multi-Omics Dissection and Functional Validation of Candidate Regulators Modulating Stress Tolerance and Xylose Utilization in the Natural Yeast Strain YB-2625. [PDF]
Cheng C +4 more
europepmc +1 more source
An investigation of the tandem Tudor domain (TTD) domain of UHRF1 identified and extensively characterized the local anesthetic hydroxyprocaine as a strong ligand capable of activating related genes such as p53 and also highlighted a new, potentially druggable intramolecular interaction between TTD and UBL.
Efstratios Tsakalidis +16 more
wiley +1 more source
Chromatin dynamics and cellular energy homeostasis. [PDF]
Suganuma T, Workman JL.
europepmc +1 more source
Enzymological studies of D-amino acid N-acetyltransferase from Saccharomyces cerevisiae
openaire +1 more source
NAT10: a potential factor to reverse tumor chemotherapy resistance and radioresistance (Review). [PDF]
Li S +8 more
europepmc +1 more source
ATR-dependent phosphorylation of the histone acetyltransferase HBO1 suppresses chromatin binding and promotes replication stress responses. [PDF]
Zong C +9 more
europepmc +1 more source

