Results 201 to 210 of about 33,968 (291)

Transcriptome–Proteome Analysis of Human Naive and Memory B Cell Subsets Reveals Isotype and Subclass‐Specific Phenotypes

open access: yesEuropean Journal of Immunology, Volume 56, Issue 3, March 2026.
We performed combined proteome and transcriptome analysis of human isotype‐defined B cell subsets. IgG4‐switched B cells were most distinct from naive B cells in terms of mRNA as well as protein expression profiles. SDR16C5 was identified as uniquely upregulated in IgG4‐switched B cells.
Jana Koers   +6 more
wiley   +1 more source

Proteomic analysis reveals phage-driven metabolic shifts and biofilm disruption in methicillin-resistant Staphylococcus aureus (MRSA). [PDF]

open access: yesWorld J Microbiol Biotechnol
Dakheel KH   +6 more
europepmc   +1 more source

Time‐Resolved Transcriptomics Reveal Core and Genotype‐Specific Pathways Underlying Thermotolerance in Wheat

open access: yesFood and Energy Security, Volume 15, Issue 2, March/April 2026.
ABSTRACT Heat stress increasingly threatens global wheat production as extreme temperature events become more frequent under climate change. To better understand the molecular basis of thermotolerance, we evaluated the heat responses of 30 elite wheat accessions and identified substantial natural variation in seedling survival (26.7%), plant height (26.
Junlong Jiang   +6 more
wiley   +1 more source

Study on the Effect of Koumiss Extract in Alleviating Non‐Alcoholic Fatty Liver Disease in Zebrafish Model by Improving Mitochondrial Function and Inhibiting Fat Deposition

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Koumiss extract, 2‐furoic acid, and α,α‐trehalose alleviate NAFLD via modulating MCIA‐related proteins. This study illustrates the proposed mechanism by which koumiss extract and its bioactive analogs—2‐furoic acid and α,α‐trehalose—ameliorate NAFLD. Molecular docking analyses revealed strong binding affinities of these compounds to MCIA proteins.
Sachula Baoyin   +7 more
wiley   +1 more source

Iron, arginine, and redox metabolism in peripheral blood mononuclear cells distinguishes sickle cell disease and pulmonary hypertension

open access: yesHemaSphere, Volume 10, Issue 3, March 2026.
Abstract Pulmonary hypertension (PH) is a severe vascular complication of sickle cell disease (SCD); yet, not all patients with SCD develop PH, and PH also arises independently. This duality underscores the need to understand their intersecting biology.
Francesca I. Cendali   +22 more
wiley   +1 more source

Construction and Characterization of a Novel Direct Electron Transfer Type Enzymatic Sensor Using Spermidine Dehydrogenase. [PDF]

open access: yesBiosensors (Basel)
Tong S   +9 more
europepmc   +1 more source

Nanomotor‐Driven Extracellular Vesicles With Effective Tissue Penetration for Targeted Therapy of Primary Ovarian Insufficiency

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
ABSTRACT Stem cells and their derived extracellular vesicles (EVs) offer hope for functional reconstruction and fertility in premature ovarian insufficiency (POI) caused by gonadotoxic drugs. However, the clinical application of EVs is impeded by their instability, limited tissue penetration, and lack of targeted delivery to ovarian injury sites. Here,
Yaoqin Mu   +7 more
wiley   +1 more source

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