Results 51 to 60 of about 69,478 (239)

Drug Critical Limits for Urgent Physician Notification

Clinical Pharmacology &Therapeutics, EarlyView.
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang, Yasmeen Ibrahim, Kyle Cheng, Gerald J. Kost   +3 more
wiley   +1 more source

The Visual Predictive Check and Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
The visual predictive check (VPC) is a standard tool for assessing pharmacometric model suitability, producing visualizations that compare observed data with simulated data such that both model structure and model variability terms can be assessed. However, real‐world data commonly reflect clinical decision‐making that adapts therapy in response to ...
Jasmine H. Hughes, Martin Bergstrand, Ron J. Keizer   +2 more
wiley   +1 more source

Surface‐Strongly Complexed BiVO4 Homojunction Photoanodes: Enabling Efficient Antibiotic Pollutant Degradation and Resource Upgrading

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Herein, a synergistic photoelectrochemical‐photothermal platform is constructed for simultaneous kanamycin remediation and resource valorization, addressing energy and environmental concerns. Photoelectrochemical (PEC) technology offers a promising approach for degrading antibiotic pollutants, yet it remains constrained by low efficiency and incomplete
Zhaoqi Wang, Yaqi He, Xiaolei Liu, Zaizhu Lou, Difei Xiao, Peng Wang, Zhaoke Zheng, Yuanyuan Liu, Hefeng Cheng, Baibiao Huang, Zeyan Wang, Dongqi Tang   +11 more
wiley   +1 more source

Effect of crocus sativus on gentamicin induced nephrotoxicity

Biological Research, 2010
Crocus sativus, known as saffron, is used in folk medicine for treatment of different types of diseases, and its anti-inflammatory and free radical scavenging activities have been demonstrated.
MARJAN AJAMI, SHAHRIAR EGHTESADI, HAMIDREZA PAZOKI-TOROUDI, ROUHOLLAH HABIBEY, SOLTAN AHMED EBRAHIMI   +4 more
doaj  

Antioxidant Potentials and Nephroprotective Effects of Methanol Extract and Dichloromethane Fraction of Root Bark of Garcinia kola (Heckel) on Gentamicin-Induced Nephrotoxic Rats

UMYU Scientifica Journal
This study investigated the nephroprotective and antioxidant effects of methanol extract (ME) and dichloromethane fraction (DCMF) from the root bark of Garcinia kola against gentamicin-induced nephrotoxicity in rats.
Ige Joseph Komolafe, Adeniyi Oluwadare Fajobi, Christianah Adebimpe Dare, Adetoun Elizabeth Morakinyo, Mukaila Babatunde Adekola, Oludele Olayemi Odekanyin, Oluokun Oluboade Oyedapo   +6 more
doaj   +1 more source

Implantable electrochemical sensors for continuous blood monitoring

FlexMat, EarlyView.
Implantable electrochemical sensors enable direct, in situ, and continuous blood monitoring, shifting diagnosis from population‐based averages to dynamic, individualized analysis. This review systematically examines the influence of the unique blood properties on sensor design.
Kuangyi Zou, Yuanzhen Wang, Haidong Wang, Ye Zhang   +3 more
wiley   +1 more source

Bee venom ameliorates gentamicin-induced kidney injury by restoring renal aquaporins and enhancing antioxidant and anti-inflammatory activities in rats

Frontiers in Pharmacology
Introduction:Gentamicin (GM) is a frequently used aminoglycoside for managing serious illnesses; nonetheless, renal complications limit its use. Bee venom (BV) is a biological toxin that exhibits anti-inflammatory and antioxidant activities.
Doaa Abdelrahaman, Obeid Shanab, Ahmed Abdeen, Afaf Abdelkader, Khalid M. Elazab, Hagar Kouriem, Zainab M. Maher, Amal S. Abu-Almakarem, Mohamed E. Mohamed, Yasser M. Elbastawisy, Yasser M. Elbastawisy, Mohamed G. Elsehrawy, Mohamed G. Elsehrawy, Abdelnaser A. Badawy, Naglaa Mokhtar, Naglaa Mokhtar, Moaz A. Mojaddidi, Madaniah O. Zakari, Samah F. Ibrahim, Dania Abdelhady, Dania Abdelhady, Laila Mostafa   +21 more
doaj   +1 more source

Antimicrobial Sensitivity Profile and Resistance Gene Research in Escherichia coli Isolated From Water and Fish From Lagoa da Conceição, Florianópolis, SC, Brazil

Food Safety and Health, EarlyView.
This paper highlights a concerning scenario of environmental contamination by multidrug‐resistant bacteria, underscoring the need for integrated surveillance and control strategies to address antimicrobial resistance in aquatic environments within the context of One Health.
Francisco Lucas de Amorim Nascimento, Luan Amaral Alexandre, Cynthia Farias Manassi, Alice Cristina da Silva, Luísa Aimée Schmitt Lobe, Gustavo Rocha, Mateus Rocha Ribas, Victor Wolleck, Gabriele Caroline Gottschalk de Abreu, Alessandra Valéria Vortmann, Sheila Mello da Silveira, Rodrigo Barcellos Hoff, Jussara Kasuko Palmeiro, Silvani Verruck   +13 more
wiley   +1 more source

Aislamiento de Staphylococcus epidermidis portador de integrón clase 1 en un paciente con sepsis neonatal Isolation of Staphylococcus epidermidis strain carrier of the class one integron in a septic neonatal patient

Infectio, 2009
Objetivo. Determinar la presencia y secuencia del integrón clase I en un aislamiento clínico de Staphylococcus epidermidis proveniente de un neonato con diagnóstico de sepsis. Materiales y métodos. En una cepa de S. epidermidis, aislada de una muestra de
Gladys Pinilla, Liliana Muñoz, Ariel Ivan Ruiz, Bibiana Chavarro, Yolanda Cifuentes   +4 more
doaj  

In vitro Activity of Apramycin Against Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae Isolates

Frontiers in Microbiology, 2020
ObjectiveThe emergence of carbapenem-resistant and hypervirulent Klebsiella pneumoniae (CR-hvKp) strains poses a significant public threat, and effective antimicrobial therapy is urgently needed.
Mingju Hao, Xiaohong Shi, Jingnan Lv, Siqiang Niu, Shiqing Cheng, Hong Du, Fangyou Yu, Yi-Wei Tang, Barry N. Kreiswirth, Haifang Zhang, Liang Chen   +10 more
doaj   +1 more source