Results 31 to 40 of about 145,462 (315)
International Journal of Antimicrobial Agents, 2020 We here assessed the co-occurrence of aminoglycoside and β-lactam resistance in 3358 consecutive Escherichia coli clinical isolates collected in 2014 in the greater Zurich area, Switzerland.
Elias Bodendoerfer +5 more
semanticscholar +1 more source
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) [PDF]
, 2019 This review focuses on the use of oxadiazoles as translational readthrough-inducing drugs (TRIDs) to rescue the functional full-length protein expression in mendelian genetic diseases caused by nonsense mutations.
Campofelice A. +6 more
core +1 more source
Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity: An experimental study [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): In this study, it is aimed to investigate the potential protective effect of caffeic acid phenethyl ester (CAPE) on ototoxicity caused by gentamicin in a rat model.Materials and Methods: Thirty Wistar albino rats were divided into 3 groups.
Fuat Aydemir +3 more
doaj +1 more source
Aminoglycoside-Induced Phosphatidylserine Externalization in Sensory Hair Cells Is Regionally Restricted, Rapid, and Reversible [PDF]
, 2008 The aminophospholipid phosphatidylserine (PS) is normally restricted to the inner leaflet of the plasma membrane. During certain cellular processes, including apoptosis, PS translocates to the outer leaflet and can be labeled with externally applied ...
Gale, Jonathan E +4 more
core +1 more source
Van Tıp Dergisi, 2021 INTRODUCTION: Aminoglycosides are used in gram-negative bacterial infection and are frequently used against Enterobacteriaceae and nonfermentative bacteria. Recently, increased resistance to aminoglycosides has been observed.
Yeliz Tanriverdi Çaycı +4 more
doaj +1 more source
Structure of the Ribosomal RNA Decoding Site Containing a Selenium-Modified Responsive Fluorescent Ribonucleoside Probe. [PDF]
, 2017 Comprehensive understanding of the structure-function relationship of RNA both in real time and at atomic level will have a profound impact in advancing our understanding of RNA functions in biology.
Boerneke, Mark A +3 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Co-administration of antibiotics with synergistic effects is one method to combat carbapenem-resistant organisms. Although the synergistic effects of tigecycline combined with aminoglycosides against carbapenem-resistant Klebsiella pneumoniae (CRKP) have
Xinqian Ma +7 more
doaj +1 more source
Aminoglycoside-Induced Cochleotoxicity: A Review
Frontiers in Cellular Neuroscience, 2017 Aminoglycoside antibiotics are used as prophylaxis, or urgent treatment, for many life-threatening bacterial infections, including tuberculosis, sepsis, respiratory infections in cystic fibrosis, complex urinary tract infections and endocarditis ...
Meiyan Jiang, T. Karasawa, P. Steyger
semanticscholar +1 more source
Cellular glutathione content in the organ of Corti and its role during ototoxicity. [PDF]
, 2015 Glutathione (GSH) is the major scavenger of reactive oxygen species (ROS) inside cells. We used live confocal imaging in order to clarify the role of GSH in the biology of the organ of Corti, the sensory epithelium of the cochlea, before, during and ...
Duchen, MR, Gale, JE, Majumder, P
core +1 more source
Structure of the bacterial ribosome at 2 Å resolution
eLife, 2020 Using cryo-electron microscopy (cryo-EM), we determined the structure of the Escherichia coli 70S ribosome with a global resolution of 2.0 Å. The maps reveal unambiguous positioning of protein and RNA residues, their detailed chemical interactions, and ...
Zoe L Watson +6 more
doaj +1 more source