Results 41 to 50 of about 13,598,018 (237)

N-ACETYLALANINE AMINOPEPTIDASE, A NEW ENZYME FROM HUMAN-ERYTHROCYTES

open access: yes, 1981
SCHONBERGER OL, Tschesche H. N-ACETYLALANINE AMINOPEPTIDASE, A NEW ENZYME FROM HUMAN-ERYTHROCYTES. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE.
Tschesche, Harald   +3 more
core   +1 more source

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

open access: yesAdvanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang   +6 more
wiley   +1 more source

Assignment of the human aminopeptidase N (peptidase E) gene to chromosome 15q13-qter

open access: yes, 1988
The gene for aminopeptidase N (EC 3.4.11.2) has been located on the human chromosome 15q13-qter using HindIII-cleaved DNA from a panel of hybrids between rodent and human cells.
Olsen, Jørgen   +13 more
core   +2 more sources

Potential Activities of Freshwater Exo- and Endo-Acting Extracellular Peptidases in East Tennessee and the Pocono Mountains

open access: yesFrontiers in Microbiology, 2018
Proteins constitute a particularly bioavailable subset of organic carbon and nitrogen in aquatic environments but must be hydrolyzed by extracellular enzymes prior to being metabolized by microorganisms.
Lauren Mullen   +8 more
doaj   +1 more source

CD13/aminopeptidase N in collagen vascular diseases [PDF]

open access: yesRheumatology International, 2003
To determine the significance of CD13/aminopeptidase N in collagen vascular diseases (CVD), we examined its activity and expression in sera and disease sites of patients with CVD. Significantly higher aminopeptidase activity was detected in bronchoalveolar lavage fluid from patients with interstitial lung diseases due to rheumatoid arthritis (RA ...
Dan, Hirohumi   +8 more
openaire   +2 more sources

Novel Potent Nonpeptide Aminopeptidase N Inhibitors with a Cyclic Imide Skeleton

open access: yes, 2016
Novel Potent Nonpeptide Aminopeptidase N Inhibitors with a Cyclic Imide ...
Hiroyuki Miyachi (360087)   +3 more
core   +1 more source

Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros.

open access: yesPLoS Neglected Tropical Diseases, 2010
BackgroundSnake bite is a major neglected public health issue within poor communities living in the rural areas of several countries throughout the world. An estimated 2.5 million people are bitten by snakes each year and the cost and lack of efficacy of
Sakthivel Vaiyapuri   +5 more
doaj   +1 more source

Molecular Imaging of Aminopeptidase N in Cancer and Angiogenesis. [PDF]

open access: yesContrast Media Mol Imaging, 2018
This review focuses on recent advances in the molecular imaging of aminopeptidase N (APN, also known as CD13), a zinc metalloenzyme that cleavesN-terminal neutral amino acids. It is overexpressed in multiple cancer types and also on the surface of vasculature undergoing angiogenesis, making it a promising target for molecular imaging and targeted ...
Schreiber CL, Smith BD.
europepmc   +4 more sources

Inactivation of interleukin-8 by aminopeptidase N (CD13) [PDF]

open access: yesJournal of Leukocyte Biology, 1995
Abstract Aminopeptidase (APN) was found to degrade interleukin-8 (IL-8) and inactivate its chemotactic activity. The chemotactic activity of IL-8 was decreased by APN or neutrophil plasma membranes dose- and time-dependently. The chemotactic activity was not inactivated in the presence of bestatin or WM15 monoclonal antibody.
N, Kanayama   +6 more
openaire   +2 more sources

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

open access: yesAnimal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu   +8 more
wiley   +1 more source

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