Results 41 to 50 of about 27,424 (235)

The apical sorting signal on human aminopeptidase N is not located in the stalk but in the catalytic head group

, 1992
Human aminopeptidase N carries an apical sorting signal on its ectodomain necessary for its correct transport to the apical membrane in Madin-Darby canine kidney cells.
Sjöström, Hans, Sjöström, Hans Gunnar, Hans Sjöström, Norén, Ove, Vogel, Lotte, Vogel, Lotte Katrine, Ove Norén, Lotte Katrine Vogel   +7 more
core   +1 more source

Porcine aminopeptidase N binds to F4(+) enterotoxigenic Escherichia coli fimbriae [PDF]

, 2016
Citation: Xia, P. P., Wang, Y. T., Zhu, C. R., Zou, Y. J., Yang, Y., Liu, W., . . . Zhu, G. Q. (2016). Porcine aminopeptidase N binds to F4(+) enterotoxigenic Escherichia coli fimbriae. Veterinary Research, 47, 7.
Yajie Zou, Liu, W., Zhu, G. Q., Zou, Y. J., Zhu, C. R., Xia, P. P., Yang, Y., Congrui Zhu, Hardwidge, Philip R., Pengpeng Xia, Guoqiang Zhu, Wang, Y. T., Philip R. Hardwidge, Ying Yang, Wei Liu, Yiting Wang   +15 more
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Purification of an Aminopeptidase Preferentially Releasing N-terminal Alanine from Cucumber Leaves and Its Identification as a Plant Aminopeptidase N [PDF]

Bioscience, Biotechnology, and Biochemistry, 2001
In this study, a highly active foliar aminopeptidase preferentially releasing N-terminal alanine from artificial substrates was purified and characterized from cucumber (Cucumis sativus L. suyo). The enzyme had a molecular mass of 200 kDa consisting of two subunits of 95 kDa. It was a metalloprotease the pH optimum of which was 8 to 9. It cleaved Ala-,
YAMAUCHI, Yasuo, EJIRI, Yukinori, TANAKA, Kiyoshi   +2 more
openaire   +2 more sources

Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros.

PLoS Neglected Tropical Diseases, 2010
BackgroundSnake bite is a major neglected public health issue within poor communities living in the rural areas of several countries throughout the world. An estimated 2.5 million people are bitten by snakes each year and the cost and lack of efficacy of
Sakthivel Vaiyapuri, Simon C Wagstaff, Kimberley A Watson, Robert A Harrison, Jonathan M Gibbins, E Gail Hutchinson   +5 more
doaj   +1 more source

Variable O-glycosylation of CD13 (aminopeptidase N)

Journal of Biological Chemistry, 1991
The monoclonal antibody AG6 was raised against HUVE cells and was confirmed as recognizing CD13 (aminopeptidase N) by its reactivity with the CD13 cDNA transfectant pipz "4". However, in sequential immunoprecipitation studies with another anti-CD13 monoclonal, WM15, neither was able to completely remove the molecules recognized by the other.
P J, O'Connell, V, Gerkis, A J, d'Apice
openaire   +2 more sources

Binding of Bacillus thuringiensis Cry1Ac toxin to Manduca sexta aminopeptidase-N receptor is not directly related to toxicity

, 1999
Bacillus thuringiensis Cry1Ac δ-endotoxin specifically binds a 115-kDa aminopeptidase-N purified from Manduca sexta midgut. Cry1Ac domain III mutations were constructed around a putative sugar-binding pocket and binding to purified aminopeptidase-N and ...
Sangadala, Sreedhara, Michael J. Adang, Adang, Michael J., Lee, Mi Kyong, Jeremy L. Jenkins, Jenkins, Jeremy L., Mi Kyong Lee, Donald H. Dean, Dean, Donald H., Sreedhara Sangadala   +9 more
core   +1 more source

Comprehensive Peptide Profiling Reveals the Influence of Streptococcus Thermophilus, Lactobacillus Delbrueckii Subsp. bulgaricus, and Endogenous Milk Proteases on the Hydrolysis of Milk Proteins During Early‐Stage Lactic Acid Fermentation

ChemFoodChem, EarlyView.
Untargeted peptide profiling investigates how S. thermophilus, Lb. bulgaricus, and endogenous milk enzymes impact proteolysis during early‐stage milk fermentation. ≥ 3000 identified peptides show the strongest influence of LB on the peptide profile and number of bioactive peptides. Shorter peptides are mostly formed by LB and hydrolyzed by ST.
Eva Beck, Lena Riedinger, Sevim Dalabasmaz, Joachim Stützer, Luisa Bähr, Rohtraud Pichner, Monika Pischetsrieder   +6 more
wiley   +1 more source

Interspecies differences in membrane-associated protease activities of thyrocytes and their relevance for thyroid cancer studies

Journal of Experimental & Clinical Cancer Research, 2012
Background To understand the role of proteases involved in human thyroid cancer progression and tissue invasion, thyrocytes from other species could potentially be used provided their characteristics are similar.
Fröhlich Eleonore, Maier Elke, Wahl Richard   +2 more
doaj   +1 more source