Molecular evolution of MAX effectors in the rice blast fungus Pyricularia oryzae [PDF]
, 2015 Fungal plant pathogens secrete proteins, termed “effectors”, that enable them to interact with their hosts and to influence the outcome of the interaction.
Charriat, F. +6 more
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Advanced Science, Volume 13, Issue 23, 23 April 2026.We identify an antagonistic ubiquitin circuit that controls cellular permissiveness to multiple coronaviruses. The deubiquitinase USP7 stabilizes the epigenetic regulator KDM6A to upregulate viral receptors, while the E3 ligase RNF40 degrades KDM6A by catalyzing K6/K11‐ubiquitin chains of KDM6A for autophagic degradation.
Meng‐Zhuo Huang +9 more
wiley +1 more source
Characterization of the Active Site and Insight into the Binding Mode of the Anti-angiogenesis Agent Fumagillin to the Manganese(II)-Loaded Methionyl Aminopeptidase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]
, 2005 EPR spectra were recorded for methionine aminopeptidase from Escherichia coli (EcMetAP-I) samples (~2.5 mM) to which one and two equivalents of Mn(II) were added (the latter is referred to as [MnMn(EcMetAP-I)]).
Bennett, Brian +3 more
core +1 more source
Advanced Science, Volume 13, Issue 19, 2 April 2026.The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan +20 more
wiley +1 more source
The Catalytic Role of Glutamate 151 in the Leucine Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e [PDF]
, 2004 Glutamate 151 has been proposed to act as the general acid/base during the peptide hydrolysis reaction catalyzed by the co-catalytic metallohydrolase from Aeromonas proteolytica (AAP).
Bzymek, Krzysztof P., Holz, Richard C.
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Two Pfam protein families characterized by a crystal structure of protein lpg2210 from Legionella pneumophila. [PDF]
, 2013 BackgroundEvery genome contains a large number of uncharacterized proteins that may encode entirely novel biological systems. Many of these uncharacterized proteins fall into related sequence families. By applying sequence and structural analysis we hope
Aravind, L +11 more
core +2 more sources
A Renal Clearable Probe for In Vivo Monoamine Oxidase (MAO) Detection
Advanced Science, Volume 13, Issue 23, 23 April 2026.A renal‐clearable Cy7‐based fluorogenic probe enables rapid and non‐invasive detection of monoamine oxidase (MAO) activity in vivo. Upon MAO‐mediated activation, the fluorescent product is efficiently excreted in urine, allowing direct quantification of enzyme overexpression.
Marcia Domínguez +13 more
wiley +1 more source
ChemBioChem, Volume 27, Issue 8, April 2026.Co2+‐charged EDTA‐based affinity function on various supports enabled metal ion affinity immobilization of a phenylalanine ammonia‐lyase (PcPAL) or an amine transaminase (VfTA). The best PcPAL forms were stable in reactions performed in 6M ammonia. Recharging the magnetic nanoparticle (MNP) form of PcPAL or VfTA after diethylenetriamine elution and ...
Máté Laurinyecz +7 more
wiley +1 more source
Heterologous Expression and Purification of \u3cem\u3eVibrio proteolyticus (Aeromonas proteolytica)\u3c/em\u3e Aminopeptidase: A Rapid Protocol [PDF]
, 2009 Metalloaminopeptidases (mAPs) are enzymes that are involved in HIV infectivity, tumor growth and metastasis, angiogenesis, and bacterial infection. Investigation of structure–function relationships in mAPs is a prerequisite to rational design of anti-mAP
Bennett, Brian, Hartley, Mariam
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Aminopeptidases of Germinated and Non-Germinated Barley
Food Technology and Biotechnology, 2009 In processes of barley plant development, various endo- and exopeptidases are involved. To determine the type and number of aminopeptidases that could participate in barley seed germination and tissue growth, their activities in extracts of non ...
Bojana Vukelić +2 more
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