Results 101 to 110 of about 8,322 (232)

CD13 expression affects glioma patient survival and influences key functions of human glioblastoma cell lines in vitro

BMC Cancer
CD13 (APN) is an Alanyl-Aminopeptidase with diverse functions. The role of CD13 for gliomas is still unknown. In this study, data of glioma patients obtained by TCGA and CGGA databases were used to evaluate the survival rate and prognostic value of CD13 ...
Wenying Zhang, Anne Blank, Irina Kremenetskaia, Anja Nitzsche, Güliz Acker, Peter Vajkoczy, Susan Brandenburg   +6 more
doaj   +1 more source

Revisiting Enzyme Replacement Therapy for Aspartylglucosaminuria: Truncated Phosphotransferase Enhances Mannose‐6‐Phosphorylation and Cellular Uptake of Aspartylglucosaminidase

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACT Aspartylglucosaminuria (AGU) is a lysosomal storage disorder caused by a deficiency of aspartylglucosaminidase (AGA), a hydrolase involved in the degradation of N‐glycosylated proteins. Currently, no approved therapies are available for AGU. Development of enzyme replacement therapy (ERT) for AGU has been hampered by the complex proteolytic ...
Antje Banning, Lidia Reznikova, Adla Murad, Ritva Tikkanen   +3 more
wiley   +1 more source

Interactive Effect of Residue Quality and Agroecologies Modulate Soil C- and N-Cycling Enzyme Activities, Microbial Gene Abundance, and Metabolic Quotient

Applied and Environmental Soil Science
Understanding interactive effect of agroecology explained by rainfall, temperature, elevation, and biochemical composition of residues on soil microbial abundance and functions is crucial for unraveling soil ecological processes.
Birhanu Agumas, Getachew Agegnehu, Tesfaye Feyisa   +2 more
doaj   +1 more source

Bt agave: why it is time to explore a new biotechnological frontier

Pest Management Science, Volume 82, Issue 9, Page 8053-8063, September 2026.
Drylands cover 41% of Earth, requiring sustainable crops. Agave, drought‐ and heat‐adapted, offers high‐value products with low water needs. Pests limit yield, yet Bacillus thuringiensis (Bt) Cry proteins, successful in other plants, remain unexploited in Agave.
Aline Vitória Corim Marim, Marcelo Falsarella Carazzolle, Gonçalo Amarante Guimarães Pereira, Carolina Rossi De Oliveira   +3 more
wiley   +1 more source

Limited evidence for soil enzyme activities mediating C:N discrepancies between microbial biomass and organic matter in year 145 of a maize‐based agroecosystem experiment

Soil Science Society of America Journal, Volume 90, Issue 5, September/October 2026.
Abstract Soil microbial biomass (MB) generally exhibits a narrower C:N than soil organic matter (SOM), creating a stoichiometric discrepancy hypothesized to be reconciled in part by C‐ and N‐acquiring enzyme activities. We used soils from an at‐equilibrium long‐term experiment to evaluate the degree to which MB C:N plasticity and enzyme activities ...
Tianze Song, Ezra Moses, Rosa Elena Ibarra López, Chammi Attanayake, Taylor B. Berkshire‐Akers, Andrew John Margenot   +5 more
wiley   +1 more source

Cropping system and nitrogen fertilization modulate soil enzyme kinetics

Soil Science Society of America Journal, Volume 90, Issue 5, September/October 2026.
Abstract The decomposition of soil organic matter and nutrient cycling are largely mediated by extracellular enzymes, yet the effect of soil management on enzyme kinetic (Michaelis constant [Km] and maximum velocity [Vmax]) remains poorly understood.
A. A. Khaleel, M. L. Thompson, M. D. McDaniel   +2 more
wiley   +1 more source

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

Journal of Animal Breeding and Genetics, Volume 143, Issue 5, Page 625-638, September 2026.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina, Ronald M. Lewis, Bradley A. Freking, Joan M. Burke, Thomas W. Murphy, Carrie S. Wilson, Luiz F. Brito   +6 more
wiley   +1 more source

Amino Acids in the Natural Food Web of Global Fishponds: Way Forward for Precision Protein Feeding in Pond Cyprinid Aquaculture

Reviews in Aquaculture, Volume 18, Issue 4, September 2026.
ABSTRACT Natural food webs in freshwater pond ecosystems provide an important nutritional foundation for cyprinid aquaculture, yet information on their protein and amino acid composition remains fragmented. This review synthesized published data from 30 studies (1950–2026) reporting protein and indispensable amino acid (IAA) composition of freshwater ...
Md. Foysul Hossain, Katerina Sezimova, Jan Mraz, Radek Gebauer, Lubos Zabransky, Koushik Roy   +5 more
wiley   +1 more source

Nitrogen Enrichment Enhances Soil Multifunctionality Through Distinct Drivers Across Urban, Suburban, and Rural Forests

Land Degradation &Development, Volume 37, Issue 14, Page 10009-10021, 30 August 2026.
ABSTRACT The accelerating pace of urban expansion has profoundly reshaped urban–rural ecosystems, altering soil environments and impairing key ecological services. However, the combined impacts of urban expansion and atmospheric nitrogen (N) deposition on soil multifunctionality—the capacity to sustain multiple ecological processes—remain poorly ...
Xu Sun, Xiao Tao, Qingshui Yu, Zhuangzhuang Qian   +3 more
wiley   +1 more source

Zinc-dependent aminopeptidases: new perspectives on structure, function, and biomedical applications

Frontiers in Chemical Biology
Zinc-dependent aminopeptidases are a subclass of exopeptidases implicated in the hydrolysis of N-terminal residues from peptides through a Zn(II) co-factor dependent hydrolytic mechanism. In humans, the prominent members of this class of enzymes (ERAP1/2,
Saleem Bhat
doaj   +1 more source