Results 71 to 80 of about 13,303 (230)
IRAP Inhibitors: M1-Aminopeptidase Family Inspiration
Frontiers in Pharmacology, 2020 The insulin regulated aminopeptidase (IRAP) has been proposed as an important therapeutic target for indications including Alzheimer’s disease and immune disorders.
Nicholas Barlow, Philip E. Thompson
doaj +1 more source
The impact of accumulating immune adaptation in circulating strains of HIV‐1
HIV Medicine, EarlyView.Abstract Background Mutations in human immunodeficiency virus type 1 (HIV‐1) enable the virus to evade recognition and killing by human leucocyte antigen (HLA)‐restricted T cells. These viral adaptations are specific to the HLA type of individuals and are therefore evident as HLA allele‐HIV sequence associations at the population level. Most studies of
Marwah Al‐kaabi +7 more
wiley +1 more source
Synthesis of New Analogues of the Bengamides: Peptidyl Bengamides and Molecular Probes [PDF]
, 2017 Isolated from sponges of the Jaspidae family, first members where discovered in 1986. The bengamides represent an interesting and unprecedented family of natural products that displayed striking antitumor activities [1].
Aguera-Suárez, Ana María +4 more
core
Journal of Animal Breeding and Genetics, EarlyView.ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina +6 more
wiley +1 more source
N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals [PDF]
, 2010 The retained N-terminal methionine (Met) residue of a nascent protein is often N-terminally acetylated (Nt-acetylated). Removal of N-terminal Met by Met-aminopeptidases frequently leads to Nt-acetylation of the resulting N-terminal alanine (Ala), valine (
Hwang, Cheol-Sang +2 more
core +1 more source
Three Decades of China's Bt Cotton: Achievements and Insights
Plant Biotechnology Journal, EarlyView.ABSTRACT Cotton is a vital natural fibre crop with significant economic value worldwide. In response to the threat of cotton bollworm (Helicoverpa armigera), the China government initiated a research project in 1992 to develop transgenic Bacillus thuringiensis (Bt) cotton.
Zhigang Meng +10 more
wiley +1 more source
, 2019 Fibromyalgia is a chronic musculoskeletal disorder which results in widespread pain, fatigue, cognitive difficulties, and emotional distress (CDC, 2017). It is also associated with abnormal pain processing.
Glennon, McKenzie K.
core +1 more source
Stereoselective synthesis of α-amino-C-phosphinic acids and derivatives [PDF]
, 2016 α-Amino-C-phosphinic acids and derivatives are an important group of compounds of synthetic and medicinal interest and particular attention has been dedicated to their stereoselective synthesis in recent years. Among these, phosphinic pseudopeptides have
Cativiela, Carlos +3 more
core +3 more sources
Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean
Plant, Cell &Environment, EarlyView.ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley +1 more source
Veterinary Record Open, Volume 13, Issue 1, June 2026.Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Eaftekhar Ahmed Rana +5 more
wiley +1 more source