Results 41 to 50 of about 363,714 (297)

Amorphous Pharmaceutical Solids.

Biomolecules and Biomedicine, 2004
Amorphous forms are, by definition, non-crystalline materials which possess no long-range order. Their structure can be thought of as being similar to that of a frozen liquid with the thermal fluctuations present in a liquid frozen out, leaving only “static” structural disorder.
openaire   +4 more sources

An Investigation of the Impact of Precipitation Temperature and Filter Cake Thickness on the Physical Stability of Amorphous Solids: A Case Study

Molecules
The purpose of this study was to resolve the issue of physical instability in amorphous solid drugs, which can result in unwanted crystallization, affecting solubility and dissolution rates.
Zunhua Li, Xu Liao, Zicheng Gong, Bowen Zhang, Asad Nawaz   +4 more
doaj   +1 more source

The Amorphous-Crystal Interface in Silicon: a Tight-Binding Simulation [PDF]

, 1998
The structural features of the interface between the cystalline and amorphous phases of Si solid are studied in simulations based on a combination of empirical interatomic potentials and a nonorthogonal tight-binding model.
Aziz, M. J., Bernstein, N., Kaxiras, E.
core   +2 more sources

Ternary Solid Dispersions: A Review of the Preparation, Characterization, Mechanism of Drug Release, and Physical Stability

Pharmaceutics, 2023
The prevalence of active pharmaceutical ingredients (APIs) with low water solubility has experienced a significant increase in recent years. These APIs present challenges in formulation, particularly for oral dosage forms, despite their considerable ...
Arif Budiman, Eli Lailasari, Neng Vera Nurani, Ellen Nathania Yunita, Gracia Anastasya, Rizqa Nurul Aulia, Ira Novianty Lestari, Laila Subra, Diah Lia Aulifa   +8 more
doaj   +1 more source

Jamming, relaxation and crystallization of a super-cooled fluid in a three-dimensional lattice

, 2011
Off-equilibrium dynamics of a three-dimensional lattice model with nearest- and next nearest-neighbors exclusions is studied. At equilibrium, the model undergoes a first-order fluid-solid transition.
Eisenberg, E., Levit, H., Rotman, Z.
core   +1 more source

Understanding Homogeneous Nucleation in Solidification of Aluminum by Molecular Dynamics Simulations [PDF]

, 2017
Homogeneous nucleation from aluminum (Al) melt was investigated by million-atom molecular dynamics (MD) simulations utilizing the second nearest neighbor modified embedded atom method (MEAM) potentials.
Baskes, Michael I., Mahata, Avik, Zaeem, Mohsen Asle   +2 more
core   +3 more sources

Color Development Mechanism of Urea–Urethane Developers for High-Performance Thermo-Sensitive Paper

Colorants
A series of compounds with both urea and urethane moieties have been developed as color developers for high-performance thermo-sensitive paper. The compounds have lower environmental loads than conventional phenolic developers.
Saori Gontani, Sakiko Takeshima, Shinya Matsumoto, Kazuo Kabashima   +3 more
doaj   +1 more source

Recent Advances in Co-Former Screening and Formation Prediction of Multicomponent Solid Forms of Low Molecular Weight Drugs

Pharmaceutics, 2023
Multicomponent solid forms of low molecular weight drugs, such as co-crystals, salts, and co-amorphous systems, are a result of the combination of an active pharmaceutical ingredient (API) with a pharmaceutically acceptable co-former.
Yuehua Deng, Shiyuan Liu, Yanbin Jiang, Inês C. B. Martins, Thomas Rades   +4 more
doaj   +1 more source

Theory of amorphous ices

, 2014
We derive a phase diagram for amorphous solids and liquid supercooled water and explain why the amorphous solids of water exist in several different forms.
Chandler, David, Limmer, David T
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source