Results 41 to 50 of about 118,015 (300)
New Nanometric Solid Dispersions of Glibenclamide in Neusilin® UFL2 [PDF]
, 2015 To improve the poor water solubility and dissolution rate of the oral hypoglycemic drug glibenclamide, it was molecularly dispersed in Neusilin® UFL2, an amorphous synthetic form of magnesium aluminometasilicate, at different proportions; the ...
Censi, Roberta +4 more
core +1 more source
Comparative study of the potential of poly(2-ethyl-2-oxazoline) as carrier in the formulation of amorphous solid dispersions of poorly soluble drugs [PDF]
, 2019 Despite the fact that solid dispersions are gaining momentum, the number of polymers that have been used as a carrier during the past 50 years is rather limited.
Boel, Eline +5 more
core +1 more source
Normal modes, and acoustic properties, of an elastic solid with line defects
, 2014 The normal modes of a continuum solid endowed with a random distribution of line defects that behave like elastic strings are described. These strings interact with elastic waves in the bulk, generating wave dispersion and attenuation.
Lund, Fernando
core +2 more sources
Averaging of the electron effective mass in multicomponent transparent conducting oxides [PDF]
, 2007 We find that layered materials composed of various oxides of cations with $s^2$ electronic configuration, $XY_2$O$_4$, $X$=In or Sc, $Y$=Ga, Zn, Al, Cd and/or Mg, exhibit isotropic electron effective mass which can be obtained via averaging over those of
Medvedeva, J. E.
core +3 more sources
Spray drying formulation of amorphous solid dispersions
Advanced Drug Delivery Reviews, 2016 Spray drying is a well-established manufacturing technique which can be used to formulate amorphous solid dispersions (ASDs) which is an effective strategy to deliver poorly water soluble drugs (PWSDs). However, the inherently complex nature of the spray drying process coupled with specific characteristics of ASDs makes it an interesting area to ...
Singh, Abhishek, Van den Mooter, Guy
openaire +4 more sources
Journal of Advanced Pharmaceutical Technology & Research, 2016 The aim of this research is to prepare and characterize solid dispersion of efavirenz – polyvinylpyrrolidone (PVP) K-30 by freeze drying to increase its solubility.
Lili Fitriani +2 more
doaj +1 more source
ADMET and DMPK, 2023 Introduction: Olanzapine (OLZ) is a psychotropic class drug commonly used to treat schizophrenia, bipolar disorder, and acute manic episodes. It has less water solubility, resulting in a slow dissolution rate and oral bioavailability.
Leena Patil +5 more
doaj +1 more source
Laser irradiation to produce amorphous pharmaceuticals [PDF]
, 2016 Using a high-power CO2 laser to irradiate powder beds, it was possible to induce phase transformation to the amorphous state. Irradiation of a model drug, indometacin, resulted in formation of a glass.
Basit, AW +3 more
core +1 more source
Myricetin Amorphous Solid Dispersions—Antineurodegenerative Potential
MoleculesOur research aimed to develop an amorphous solid dispersion (ASD) of myricetin (MYR) with Polyvinylpyrrolidone K30 (PVP30) to enhance its solubility, dissolution rate, antioxidant, and neuroprotective properties. Employing a combination of solvent evaporation and freeze drying, we successfully formed MYR ASDs.
Natalia Rosiak +2 more
openaire +3 more sources
Discontinuous shear modulus determines the glass transition temperature
, 2015 A solid - amorphous or crystalline - is defined by a finite shear modulus while a fluid lacks such. We thus experimentally investigate the elastic properties of a colloidal glass former near the glass transition: spectroscopy of vibrational excitations ...
Keim, Peter +2 more
core +2 more sources