Results 31 to 40 of about 118,785 (293)
Solid dispersion is one of the most promising strategies to improve oral bioavailability of poorly soluble API. However, there are inconsistent dissolution performances of solid dispersion reported which entails further investigation.
Siok-Yee Chan +4 more
doaj +1 more source
Processing-Induced Disorder in Pharmaceutical Materials [PDF]
This chapter focuses on the major types of pharmaceutical processing methods that have been widely reported to produce disordered material either intentionally or unintentionally.
Al-Obaidi +89 more
core +1 more source
Structural, electrical and catalytic properties of ion-implanted oxides [PDF]
The potential application of ion implantation to modify the surfaces of ceramic materials is discussed. Changes in the chemical composition and microstructure result in important variations of the electrical and catalytic properties of ...
Burggraaf, A.J., Hassel, B.A. van
core +4 more sources
Solid Dispersion Technology for Improving the Solubility of Antiviral Drugs
Most drugs, including antiviral drugs, show low solubility in water, which affects dissolution, bioavailability, and therapeutic effectiveness. Therefore, many antiviral drugs are given in very large doses.
Maria Elvina Tresia Butar-Butar +3 more
doaj +1 more source
This study aimed to improve the solubility and dissolution of aprepitant, a drug with poor aqueous solubility, using a phosphatidylcholine (PC)-based solid dispersion system.
Sooho Yeo +4 more
doaj +1 more source
Ultrafast dephasing of coherent optical phonons in atomically controlled GeTe/Sb$_{2}$Te$_{3}$ superlattices [PDF]
Femtosecond dynamics of coherent optical phonons in GeTe/Sb$_{2}$Te$_{3}$ superlattices (SLs), a new class of semiconductor SLs with three different states, have been investigated by using a reflection-type pump-probe technique at various lattice ...
Junji Tominaga +4 more
core +2 more sources
Harmonic behavior of metallic glasses up to the metastable melt [PDF]
In two amorphous alloys ZrTiCuNiBe and ZrAlNiCu coherent neutron scattering has been measured over five decades in energy, including measurements in the metastable melt of a metallic alloy more than 80 K above Tg. In the vibrational spectra a pronounced "
Bormann, R. +8 more
core +1 more source
Amorphous salt solid dispersion (ASSD) of Dolutegravir amorphous salt (DSSD) was generated using quench cooling and compared to its Dolutegravir free acid solid dispersion (DFSD) to improve the solubility and bioavailability. Soluplus (SLP) was used as a
Dani Lakshman Yarlagadda +3 more
doaj +1 more source
Propagating elastic vibrations dominate thermal conduction in amorphous silicon [PDF]
Thermal atomic vibrations in amorphous solids can be distinguished by whether they propagate as elastic waves or do not propagate due to lack of atomic periodicity.
Latour, Benoit +2 more
core +3 more sources
Carvedilol (CVD) is a non-selective β-blocker. CVD is included in BCS class II. It has low water solubility. In this research, solid dispersion was used to increase the solubility and dissolution profile of CVD.
Iyan Sopyan +3 more
doaj +1 more source

