Results 131 to 140 of about 2,373,510 (375)
The spectrum of Ischemia-induced white matter injury varies with age [PDF]
Stroke is a neurological condition that targets the whole range of the human population, from the pre-term infant to the elderly and is a major cause of death worldwide (Ingall 2004).
Muscat, Richard+2 more
core +1 more source
Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha+6 more
wiley +1 more source
Differential Regulation of AMPA Receptor and GABA Receptor Trafficking by Tumor Necrosis Factor-α
The proinflammatory cytokine tumor necrosis factor-α (TNFα) causes a rapid exocytosis of AMPA receptors in hippocampal pyramidal cells and is constitutively required for the maintenance of normal surface expression of AMPA receptors.
D. Stellwagen+3 more
semanticscholar +1 more source
ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao+6 more
wiley +1 more source
LTD expression is independent of glutamate receptor subtype
Long-term depression (LTD) is a form of synaptic plasticity that plays a major role in the activity-dependent reshaping of synaptic transmission.
Adam J Granger, Roger A Nicoll
doaj +1 more source
Recent updates on incubation of drug craving: a mini-review [PDF]
Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural ...
Abdolahi+39 more
core +1 more source
Intratumoral Nerve Phased Development: A Promising Therapeutic Target
ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che+3 more
wiley +1 more source
Calcium-Permeable AMPA Receptors in the Retina [PDF]
The retina transforms light entering the eye into a sophisticated neural representation of our visual world. Specialized synapses, cells, and circuits in the retina have evolved to encode luminance, contrast, motion, and other complex visual features. Although a great deal has been learned about the cellular morphology and circuitry that underlies this
openaire +4 more sources
Pregnenolone Reduces L‐Dopa‐Induced Dyskinesias in Female Parkinsonian Monkeys
Pregnenolone is the first neurosteroid synthesized from cholesterol in the brain. Ovariectomized female monkeys were tested as a model of women in menopause. They were lesioned with MPTP modeling Parkinson's disease and treated with levodopa (L‐dopa) to induce dyskinesias.
Mélanie Bourque+5 more
wiley +1 more source
All roads lead to glutamate: NMDA and AMPA receptors as targets for rapid-acting antidepressants
Treatment-resistant depression (TRD) represents a major clinical challenge. Affecting about 30 % of major depressive disorder (MDD) patients, effective treatments for TRD are urgently needed.
Florian Freudenberg+4 more
doaj +1 more source