Results 131 to 140 of about 2,334,241 (398)
Arthritis &Rheumatology, Accepted Article.Objectives Rheumatoid arthritis (RA) associated anti‐citrullinated protein antibodies (ACPA) target various antigens by binding short citrulline‐amino acid motifs, resulting in heterogeneous ACPA‐profiles among patients. Here we analyzed ACPA‐patterns by recognized citrulline‐motifs in relation to the RA risk factors HLA‐DRB1 shared epitope (SE ...
Linda Mathsson Alm +31 more
wiley +1 more source
The Journal of Headache and Pain, 2020 Background Purine receptors play roles in peripheral and central sensitization and are associated with migraine headache. We investigated the possibility that ATP plays a permissive role in the activation of AMPA receptors thus inducing Glu release from ...
Diego Currò +3 more
doaj +1 more source
AMPA, NMDA and GABAA receptor mediated network burst dynamics in cortical cultures in vitro [PDF]
Proc. Int. Works. Comp. Syst. Biol. TICSP series 8 (2011) 181-184, 2018 In this work we study the excitatory AMPA, and NMDA, and inhibitory GABAA receptor mediated dynamical changes in neuronal networks of neonatal rat cortex in vitro. Extracellular network-wide activity was recorded with 59 planar electrodes simultaneously under different pharmacological conditions.
arxiv
AMPA-Net: Optimization-Inspired Attention Neural Network for Deep Compressed Sensing [PDF]
2020 IEEE 20th International Conference on Communication
Technology(Oral), 2020 Compressed sensing (CS) is a challenging problem in image processing due to reconstructing an almost complete image from a limited measurement. To achieve fast and accurate CS reconstruction, we synthesize the advantages of two well-known methods (neural network and optimization algorithm) to propose a novel optimization inspired neural network which ...
arxiv
Molecular constituents of neuronal AMPA receptors [PDF]
The Journal of Cell Biology, 2005 Dynamic regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) underlies aspects of synaptic plasticity. Although numerous AMPAR-interacting proteins have been identified, their quantitative and relative contributions to native AMPAR complexes remain unclear.
Fukata, Yuko +6 more
openaire +3 more sources
Role of Glutamate Excitotoxicity in Glioblastoma Growth and Its Implications in Treatment
Cell Biology International, EarlyView.ABSTRACT Glioblastoma is a highly malignant and invasive type of primary brain tumor that originates from astrocytes. Glutamate, a neurotransmitter in the brain plays a crucial role in excitotoxic cell death. Excessive glutamate triggers a pathological process known as glutamate excitotoxicity, leading to neuronal damage.
Colin Moriarty +2 more
wiley +1 more source
Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains
eLife, 2017 Ion conductivity and the gating characteristics of tetrameric glutamate receptor ion channels are determined by their subunit composition. Competitive homo- and hetero-dimerization of their amino-terminal domains (ATDs) is a key step controlling assembly.
Huaying Zhao +5 more
doaj +1 more source
Potential wells for AMPA receptors organized in ring nanodomains [PDF]
arXiv, 2013 By combining high-density super-resolution imaging with a novel stochastic analysis, we report here a peculiar nano-structure organization revealed by the density function of individual AMPA receptors moving on the surface of cultured hippocampal dendrites.
arxiv
A Thermodynamic Model for Receptor Clustering [PDF]
, 1999 Intracellular signaling often arises from ligand-induced oligomerization of cell surface receptors. This oligomerization or clustering process is fundamentally a cooperative behavior between near-neighbor receptor molecules; the properties of this cooperative process clearly affects the signal transduction.
arxiv +1 more source
Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study [PDF]
, 2018 Indexación: Scopus.Laboratory of Neuroplasticity and Neurogenetics, Department of Biochemistry and Molecular Biology, Faculty of Chemistry and Pharmaceutical Sciences, Universidad de Chile, Santiago, Chile, 2Laboratorio Farmacología del Comportamiento ...
Ana M. Avalos +13 more
core +2 more sources