Results 141 to 150 of about 99,629 (284)

Deciphering SCN2A: A comprehensive review of rodent models of Scn2a dysfunction

open access: yesEpilepsia, EarlyView.
Abstract SCN2A encodes for the alpha subunit of the voltage‐gated sodium channel NaV1.2, which is involved in action potential initiation and backpropagation in excitatory neurons. Currently, it is one of the highest monogenetic risk factors for both epilepsy and autism spectrum disorder.
Katelin E. J. Scott   +2 more
wiley   +1 more source

A Scoping Review of Corticosterone-Induced Changes in Ionotropic Glutamate Receptor Levels and Localization in the Rodent Brain: Implications for the Auditory System

open access: yesBrain Sciences
Background: The ionotropic glutamate receptor AMPA (AMPAR) mediates fast excitatory synaptic transmission and regulates synaptic strength in various parts of the CNS.
Elsa Edlund   +3 more
doaj   +1 more source

Anti-convulsive and anti-hypoxic effects of YM90K, a selective and potent AMPA/kainate receptor antagonist.

open access: gold, 1994
Mika Katoh   +4 more
openalex   +1 more source

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun   +6 more
wiley   +1 more source

Neocortical neurogenesis: a proneural gene perspective

open access: yesThe FEBS Journal, EarlyView.
The neocortex is a mammalian‐specific brain region responsible for higher‐order cognitive functioning that shares fundamental similarities across species, but which is larger and more complex in humans. Proneural genes, encoding basic helix–loop–helix transcription factors (TFs), are evolutionarily conserved drivers of neurogenesis from fly to human ...
Lakshmy Vasan   +3 more
wiley   +1 more source

Cell Type and Pathway Dependence of Synaptic AMPA Receptor Number and Variability in the Hippocampus

open access: bronze, 1998
Zoltán Nusser   +5 more
openalex   +1 more source

Facilitation of olfactory learning by a modulator of AMPA receptors [PDF]

open access: hybrid, 1995
John Larson   +6 more
openalex   +1 more source

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