Results 131 to 140 of about 58,960 (255)
CaV1.2 dynamics in native male arterial myocytes
Abstract figure legend Proposed model of microtubule‐dependent CaV1.2 reorganization in vascular disease. Schematic illustration of microtubule‐mediated delivery and stabilization of CaV1.2 channels into enlarged plasma membrane clusters in response to Ang II or hyperglycaemia, promoting cooperative gating and enhanced Ca2+ influx. Abstract L‐type CaV1.
Miguel Martin‐Aragon Baudel +9 more
wiley +1 more source
AMPA receptor trafficking and synaptic plasticity
grantor: University of TorontoAMPA receptors are a subtype of glutamate receptors which are responsible for most of the fast excitatory synaptic transmissions in the mammalian central nervous system.
Man, Hengye
core +1 more source
AMPA receptor subunit binding to lectins.
AMPA receptor subunits from frontal cortex of rat, tree shrew, macaque and human cortex were purified with 15 biotinylated lectins (Figure 5).
Micah S. Simmons (549017) +3 more
core +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
Padrão da expressão de proteínas ligantes de cálcio e receptores de glutamato do tipo AMPA em núcleos pré-tectais de pintos (Gallus domesticus) [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Mestrado em NeurociênciasUma das características da visão perfeita é a capacidade de fixar o olhar sobre o alvo desejado.
Santos, Rita de Cássia dos
core
Early Developmental Neuronal Activity Impacts Oligodendrocyte Differentiation Through AMPA Receptors
In early brain development, neuronal activity reduces OPC differentiation. Decreased neuronal activity changes oligodendrocyte gene expression, including upregulating glutamate receptor genes. AMPA signaling regulates the final stages of OPC differentiation.
Tessa E. Allen +4 more
wiley +1 more source
ABSTRACT Lead is a toxic heavy metal with significant health risks, as maternal lead exposure during pregnancy disrupts fetal neural development through placental transfer, leading to persistent neurological, developmental, and long‐term health consequences in the progeny.
P. Harshitha +3 more
wiley +1 more source
Background: The ionotropic glutamate receptor AMPA (AMPAR) mediates fast excitatory synaptic transmission and regulates synaptic strength in various parts of the CNS.
Elsa Edlund +3 more
doaj +1 more source
ABSTRACT Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was to further explore this pathway.
Nicolas Macian +8 more
wiley +1 more source
Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu +8 more
wiley +1 more source

