Results 171 to 180 of about 94,035 (378)

Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein.

, 1992
Gregg L. Caporaso, Sam Gandy, Joseph D. Buxbaum, Paul Greengard   +3 more
openalex   +1 more source

The role of cytosolic phospholipase A₂α in amyloid precursor protein induction by amyloid beta_1-42: implication for neurodegeneration [PDF]

, 2014
Chen Sagy‐Bross, Ksenia Kasianov, Yulia Solomonov, Alex Braiman, Alon Friedman, Nurit Hadad, Rachel Lévy   +6 more
openalex   +1 more source

Design Principles Of Inorganic‐Protein Hybrid Materials for Biomedicine

Exploration, EarlyView.
Inorganic protein hybrid materials (IPHMs) due to editable structure present unrivalled potential at the intersection of synthetic biology and materials science. The synthesis of IPHMs with a high degree of biosafety from bioactive units represents a shift in material design and synthesis.
Hao Liu, Xiaohui Liu, Hui Jiang, Xuemei Wang   +3 more
wiley   +1 more source

Péptido beta amiloide, proteína Tau y enfermedad de Alzheimer

Revista Cubana de Investigaciones Biomédicas, 2002
Se realizó una actualización sobre la enfermedad de Alzheimer, que constituye la causa más frecuente de demencia. Se establecieron aspectos relacionados con los cromosomas 21 y 17.
Silvia Gra Menéndez, Noel Padrón Pérez, Juan de Jesús Llibre Rodríguez   +2 more
doaj  

A direct role for protein kinase C and the transcription factor Jun/AP-1 in the regulation of the Alzheimer's beta-amyloid precursor protein gene.

, 1994
JoAnn Trejo, Tania Massamiri, T Deng, Nazneen N. Dewji, Richard M. Bayney, Joan Heller Brown   +5 more
openalex   +1 more source

Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling [PDF]

, 2020
Claire S. Durrant, Karsten Ruscher, Olivia Sheppard, Michael P. Coleman, Ílknur Özen   +4 more
openalex   +1 more source

Inflammation Combined with Ischemia Produces Myelin Injury and Plaque-Like Aggregates of Myelin, Amyloid-β and AβPP in Adult Rat Brain. [PDF]

, 2015
BackgroundIschemia, white matter injury, and Alzheimer's disease (AD) pathologies often co-exist in aging brain. How one condition predisposes to, interacts with, or perhaps causes the others remains unclear.ObjectivesTo better understand the link ...
Ander, Bradley P, Cox, Christopher, Jickling, Glen C, Jin, Lee-Way, Liu, Dazhi, Sharp, Frank R, Stamova, Boryana, Zhan, Xinhua   +7 more
core  

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

Exploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang, Ying Liu, Xiadong Zhu, Lizhen He, Tianfeng Chen   +4 more
wiley   +1 more source

Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes [PDF]

, 2015
Weihao Tang, Joshua H. K. Tam, Claudia Seah, Justin Chiu, Andrea Tyrer, Sean P. Cregan, Susan O. Meakin, Stephen Pasternak   +7 more
openalex   +1 more source

Hypothesis review: Alzheimer's overture guidelines

Brain Pathology, Volume 33, Issue 1, January 2023., 2023
Brain aging with ADNC and sporadic Alzheimer's disease (sAD) form a prevalent continuum unique to humans. Molecular changes affecting cell membranes, cytoskeleton, synapses, lipid and protein metabolism, energy metabolism, neuroinflammation, cell cycle, astrocytes, microglia, and blood vessels precede and occur in parallel with early ADNC; and they are
Isidro Ferrer
wiley   +1 more source