Results 151 to 160 of about 4,375,511 (236)

Amyloid Precursor Protein Processing Links Female Urgency Urinary Incontinence with Alzheimer's Disease: Implications for Treatment. [PDF]

Int J Mol Sci
Post WM, Widomska J, Oosterwijk E, De Witte W, Tiemessen DM, Klemann CJHM, Ruisch IH, Coenen MJH, Janssen DAW, Martens F, Carnes MU, Marks JA, Page GP, Richter HE, Cartwright R, Minassian VA, Thomas LF, Skogholt AH, Stafne SN, Hveem K, Kluivers KB, Poelmans G.   +21 more
europepmc   +1 more source

Effect of acute ischemic stroke in 3xTg-AD mouse model of Alzheimer's disease. [PDF]

Sci Rep
Yadav SK, Srivastava R, Yadawa AK, Gamiotea-Turro D, Verma R.   +4 more
europepmc   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Increased Amyloidogenic Neuronal Injury in HIV-1-infected APP-KI Alzheimer's disease mice. [PDF]

Alzheimers Dement
Bhattarai S, Foster EG, Kadry R, Lu Y, Kumar M, Qasim S, Mitra A, Pathak H, Poluektova LY, Gorantla S, Mosley RL, Yeapuri P, Gendelman HE.   +12 more
europepmc   +1 more source

Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions

Brain Pathology, EarlyView.
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich, David S. Priemer, Charles Harker Rhodes, Daniel P. Perl, Kurenai Tanji, James E. Goldman   +5 more
wiley   +1 more source

Amyloid Alpha: The Neglected Cousin of Amyloid Beta. [PDF]

Chembiochem
Raskatov JA.
europepmc   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

Brain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu, Yoshiki Takai, Naoya Yamazaki, Sarah Brandl, Katharina M. Mair, Thibault Bouderlique, Maria Eleni Kastriti, Igor Adameyko, Romana Höftberger, Markus Reindl, Jan Bauer, Monika Bradl   +11 more
wiley   +1 more source

Emerging neuroprotective mechanisms and therapeutic potential of natural polysaccharides in Alzheimer's disease. [PDF]

Front Aging Neurosci
Muhammad N, Ai R, Yang L, Cui Y, Wang L, Weng S, Wang Y, Kakar MU, Khan S, Ahmad S, Iqbal I.   +10 more
europepmc   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Glycyrrhizin Ameliorates Learning and Memory Impairment via Inhibition of Neuroinflammation in an Alzheimer's Disease Mouse Model SAMP8. [PDF]

Int J Mol Sci
Wang G, Hiramoto K, Ma N, Ohnishi S, Yoshikawa N, Murata M, Kawanishi S.   +6 more
europepmc   +1 more source