Results 151 to 160 of about 86,737 (312)

Impact of aging : sporadic, and genetic risk factors on vulnerability to apoptosis in Alzheimer's disease

, 2003
The identification of specific genetic (presenilin-1 [PS1] and amyloid precursor protein [APP] mutations) and environmental factors responsible for Alzheimer's disease (AD) has revealed evidence for a shared pathway of neuronal death.
Steiner, Barbara, Maurer, Konrad, Czech, Christian, Schindowski, Katharina, Leutner, Silke, Frölich, Lutz, Eckert, Anne, Pradier, Laurent, Kratzsch, Tilmann, Peters, Jürgen, Touchet, Natalie, Müller, Walter E.   +11 more
core  

Amyloid β alters vascular CaV1.2 channel spatiotemporal properties

The Journal of Physiology, EarlyView.
Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor, Miguel Martin‐Aragon Baudel, Eric Pereira da Silva, Johannes W. Hell, Madeline Nieves‐Cintron, Manuel F. Navedo   +5 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Studio della regolazione della maturazione proteolitica del precursore del peptide β amiloide APP

, 2006
[ITALIANO] Il peptide β amiloide presente nelle placche senili nella malattia di Alzheimer deriva dal taglio della proteina di membrana APP. In questo lavoro di tesi e’ stato sviluppato un sistema sperimentale per identificare possibili segnali ...
Gianni, Davide
core  

Relation of the Amyloid β Protein Precursor to Heparan Sulfate Proteoglycans [PDF]

Science, 1989
D C, Gowda, R K, Margolis, B, Frangione, J, Ghiso, M, Larrondo-Lillo, R U, Margolis   +5 more
openaire   +2 more sources

Resveratrol: Advance on the Most Recent Research From 2021 to 2025

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
This review summarizes recent progress in resveratrol research (2021–2025), highlighting its natural sources, bioactivities, clinical evidence, and safety profiles. Resveratrol exerts multi‐target effects through the regulation of oxidative stress, inflammation, mitochondrial function, and gut microbiota.
Quanyong Wu, Boya Ouyang, Yi Yuan, Jesus Simal‐Gandara, Hui Cao   +4 more
wiley   +1 more source

Micro‐ and Nanostructured Materials in Edible Coatings for the Preservation of Fruits and Vegetables

eFood, Volume 7, Issue 4, August 2026.
Graphical representation of micro‐ and nanostructured materials in edible coatings for the preservation of fruits and vegetables. ABSTRACT Edible coatings based on advanced nanostructured materials have emerged as effective strategies for extending the shelf life and maintaining the quality of fresh fruits and vegetables.
Carlos Méndez‐Durazno, Katherine Vaca‐Escobar, Fernanda Landeta‐Constante, Santiago Guerrero‐Jaramillo, Milton Villacís‐García, Patricio J. Espinoza‐Montero   +5 more
wiley   +1 more source

Astrocytoma-Specific Prognostic Associations of Amyloid-Related Biological Processes. [PDF]

Pathophysiology
Narvaez Irizarry FY, Porter TR, Ramirez Serrano N, Kucheryavykh LY.   +3 more
europepmc   +1 more source

Plasma Membrane Remodeling During Microglial Activation: A Hypothesis Linking Microglial Shape and Lipid Droplet Formation

Glia, Volume 74, Issue 8, August 2026.
Microglial morphology changes in response to damage by Aβ and aging result in significant reductions in cell surface area. Transcriptomic analyses suggest that fatty acid synthesis and triacylglycerol formation drive redistribution of surface membrane into intracellular lipid droplets.
G. William Rebeck, Giorgi Shautidze, Jordy Sepulveda, Gracie S. Healey, Priyanka S. Narayan   +4 more
wiley   +1 more source

Amyloid Alpha: The Neglected Cousin of Amyloid Beta. [PDF]

Chembiochem
Raskatov JA.
europepmc   +1 more source