Results 221 to 230 of about 122,310 (350)

The role of neutrophils, red blood cells, and platelets in the pathology of Alzheimer's disease. [PDF]

Ann Med
Xu Y, Li X, Zhao Q, Xu X.
europepmc   +1 more source

Alzheimer beta A4-amyloid protein precursor in immunocompetent cells.

, 1992
U. Mönning, Gerhard König, Richard B. Banati, Hans Mechler, Christian Czech, Jochen Gehrmann, Ursula Schreiter-Gasser, Colin L. Masters, Konrad Beyreuther   +8 more
openalex   +1 more source

Deficiency of Microglial‐Derived Spp1 Exacerbates Age‐Related Memory Decline by Impairing Mitochondrial Complex I Function

Aging Cell, Volume 25, Issue 2, February 2026.
Microglia‐derived Spp1 regulates OXPHOS via the AKT/Complex I pathway to mitigate age‐related memory decline. (Graphical Abstract was created using BioRender). ABSTRACT Age‐related memory decline is a hallmark of brain aging and a primary risk factor for neurodegenerative disorders.
Meiling Wang, Yumin Chang, Aojie He, Jing Yang, Ang Li, Hongqin Wang, Kah‐Leong Lim, Xing Guo, Chengwu Zhang, Li Lu   +9 more
wiley   +1 more source

Referee report. For: Identification of high-performing antibodies for amyloid-beta precursor protein for use in Western Blot, immunoprecipitation and immunofluorescence [version 1; peer review: 1 approved with reservations]

Amal Kaddoumi
openalex   +1 more source

A complex network perspective on brain disease

Biological Reviews, Volume 101, Issue 1, Page 364-399, February 2026.
ABSTRACT If brain anatomy and dynamics have a complex network structure as it has become standard to posit, it is reasonable to assume that such a structure should play a key role not only in brain function but also in brain dysfunction. However, exactly how network structure is implicated in brain damage and whether at least some pathologies can be ...
David Papo, Javier M. Buldú
wiley   +1 more source

Evaluation of a New Methylimidazole‐Containing Thiosemicarbazone as a Cu+/Cu2+‐Targeting Ligand in the Context of Alzheimer's Disease

Chemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
HXE modulates Cu(Aβ) interaction, reducing ROS production and shifting peptide aggregation in the presence of Cu from toxic amorphous aggregates to less harmful fibrillar structures. These findings highlight HXE potential to interfere with Cu‐induced oxidative stress and aggregation pathways relevant to AD.
Barbara Marinho Barbosa, Charlène Esmieu, Antal Galvácsi, Mariana Viana Costa, Adèle Brison, Sonia M. Ladeira, Jade de Oliveira, Csilla Kállay, Christelle Hureau, Nicolás A. Rey   +9 more
wiley   +1 more source

Beta-amyloid influences the content and trafficking of beta-amyloid precursor protein via Na,K-ATPase-Src kinase positive feedback loop. [PDF]

Front Pharmacol
Petrushanko IY, Lisitskii DR, Filonov FA, Leonova OG, Mitkevich VA, Strelkova MA, Makarov AA.   +6 more
europepmc   +1 more source

Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage.

, 1992
Albert Y. Hung, Edward H. Koo, Ch. Haass, Dennis J. Selkoe   +3 more
openalex   +2 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, Volume 600, Issue 1, Page 109-118, January 2026.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source