Results 241 to 250 of about 86,737 (312)

Ketone-Dependent Restoration of Autophagy and Mitochondrial Quality Control Through VPS35 in a Drosophila Model of C99-Induced Neurodegeneration. [PDF]

Cells
Huang H, Xu K, Lardellia M.
europepmc   +1 more source

Cortical gray–white matter contrast alterations precede amyloid‐β positivity and macrostructural changes in older adults without dementia

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Early Alzheimer's disease (AD) involves subtle cortical changes that may precede atrophy. Magnetic resonance imaging (MRI) microstructural markers may detect earlier pathology than classical morphometry. METHODS We analyzed cross‐sectional MRI and amyloid‐β (Aβ) positron emission tomography (PET) data from 1323 non‐demented AMYPAD
Leonard Pieperhoff, Luigi Lorenzini, Francisco Almeida, Mario Tranfa, Ariane Bollack, Prithvi Arunachalam, Federico Masserini, Robin Wolz, Sylke Grootoonk, Craig Ritchie, Mercè Boada, Marta Marquié, Jort Vijverberg, Rik Vandenberghe, Bernard J. Hanseeuw, Pablo Martinez‐Lage, Pierre Payoux, Pieter Jelle Visser, Michael Schöll, Giovanni B. Frisoni, Matteo Pardini, Luca Roccataglia, Andrew W. Stephens, Chris Buckley, Gill Farrar, Frank Jessen, Juan Domingo Gispert, Gemma Salvadó, Emma S. Luckett, Henk‐Jan MM Mutsaerts, Alle Meije Wink, Lyduine E. Collij, Frederik Barkhof, Tiago Gil Oliveira, the AMYPAD consortium   +34 more
wiley   +1 more source

Plasma Beta-Amyloid and Metabolic Biomarkers: Age- and Sex-Stratified Analyses Suggest Limited Population-Level Associations. [PDF]

Medicina (Kaunas)
Yun H, Jung BK, Kim JK.
europepmc   +1 more source

Novel Monoclonal Antibody Detects Small Aβ Oligomers More Sensitively Than Lecanemab in Alzheimer's Disease CSF, Serum and Culture Media

Annals of Neurology, Volume 99, Issue 6, Page 1452-1465, June 2026.
Objective Aqueously diffusible oligomers of the amyloid β‐protein (oAβ) are neurotoxic and play a role in neuronal dysfunction in Alzheimer's disease (AD). Accurate quantification of oAβ in brains and biofluids could be valuable for understanding and monitoring AD.
Yi Ran Xu, Youqi Tao, Alexandra M. Lish, Shaomin Li, Beth L. Ostaszewski, Amirah K. Anderson, Tracy Young‐Pearse, Trebor L. Lawton, Hyun‐Sik Yang, Dominic M. Walsh, Ting Yang, Dennis J. Selkoe   +11 more
wiley   +1 more source

Amyloid precursor protein is a subunit of microglial Hv1 channels. [PDF]

Curr Opin Immunol
Zhao R, Goldstein SA.
europepmc   +1 more source

Effects of Wheat Malt Extract on Molecular and Behavioral Markers in Aged APP/PS1 and Wild-Type Mice. [PDF]

Int J Mol Sci
Kassenova A, Svirin E, Sitdikova K, Chaprov K, Tsoy A, Munter J, Nurzhanov A, Kuznetsova M, Veremeyko T, Deykin A, Ponomarev E, Strekalova T, Askarova S.   +12 more
europepmc   +1 more source

PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer's disease model. [PDF]

Proc Natl Acad Sci U S A
Jhaldiyal A, Kumari M, Guttman LC, Tripathi T, Khan MR, Wang J, Biswas D, Pasupuleti A, Aggarwal A, Pandya S, Chou SC, Panicker N, Monghekar A, Albert M, Bekris LM, Leverenz JB, Kam TI, Dawson TM, Dawson VL.   +18 more
europepmc   +1 more source

Amyloid-β 1-42 fibrils regulate SH-SY5Y cell adhesion in a delayed manner. [PDF]

J Alzheimers Dis
Pečar Fonović U, Kralj S, Kos J.
europepmc   +1 more source

Complementary DNA for the mouse homolog of the human amyloid beta protein precursor

, 1989
openaire   +1 more source