Results 271 to 280 of about 122,310 (350)

Alzheimer's disease polygenic risk in early‐ and late‐onset Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION The genetic basis of sporadic early‐onset Alzheimer's disease (EOAD) remains largely unknown, prompting evaluation of late‐onset Alzheimer's disease (LOAD) polygenic risk in EOAD. METHODS A LOAD polygenic score (PGS) was calculated in the Longitudinal Early‐onset Alzheimer's Disease Study (LEADS) and Alzheimer's Disease ...
Julian V. Pentchev, Trever Jackson, Naazneen Khan, Thea J. Rosewood, Yen‐Ning Huang, Kwangsik Nho, Andrew J. Saykin, Ani Eloyan, Alexander Taurone, Maryanne Thangarajah, Meghan Riddle, Steven Salloway, Alireza Atri, Lawrence S. Honig, Erik C. B. Johnson, Raymond Scott Turner, Joseph C. Masdeu, Tatiana M. Foroud, David Clark, Dustin B. Hammers, Jeffrey L. Dage, Kala Kirby, Bernardino Ghetti, Kathy Newell, Chiadi U. Onyike, Gregory S. Day, Neill R. Graff‐Radford, Melissa E. Murray, David T. Jones, Clifford R. Jack Jr., Prashanthi Vemuri, Alexandra Touroutoglou, Ranjan Duara, Ian Grant, Sharon Sha, Thomas S. Wingo, Laurel A. Beckett, Emily Rogalski, Mario F. Mendez, Joel Kramer, Renaud La Joie, Ganna Blazhenets, Lea T. Grinberg, Robert Koeppe, David A. Wolk, Paul Aisen, Rema Raman, Arthur Toga, Walter A. Kukull, Erik Musiek, Kyle B. Womack, Maria C. Carrillo, Gil D. Rabinovici, Bradford C. Dickerson, Liana G. Apostolova, Kelly N. H. Nudelman, for the Longitudinal Early‐Onset Alzheimer's Disease Study Consortium and the Alzheimer's Disease Neuroimaging Initiative   +56 more
wiley   +1 more source

Investigating the binding potential of the Melissa officinalis oil against Alzheimer's targets by molecular docking and in vitro evaluations. [PDF]

Sci Rep
Kolouei A, Barati M, Abbas-Mohammadi M.
europepmc   +1 more source

The Alzheimer's disease beta amyloid protein precursor : analysis of the carboxyl terminus of its soluble derivatives.

, 1992
J. M. Pasternack
openalex   +1 more source

Aβ antibodies target not only amyloid plaques but also distinct brain cells and vessels. [PDF]

Alzheimers Dement
Wen G, Lindblom N, Zhan X, Garcia-Ryde M, Deierborg T, Kobro-Flatmoen A, Gouras GK.   +6 more
europepmc   +1 more source

Iatrogenic cerebral amyloid angiopathy 30 years after childhood cadaveric dura mater transplantation: a case report. [PDF]

BMC Neurol
Takai I, Ogawa T, Oji Y, Yayama A, Imanishi Y, Taniguchi D, Matsuoka G, Kato M, Nakamura R, Watanabe M, Yamashiro K, Ikeuchi T, Hattori N, Urabe T.   +13 more
europepmc   +1 more source

An unexpected discovery of a novel potentially pathogenic APP gene variant: a case report of slowly progressive Alzheimer's disease with prominent cerebral amyloid angiopathy. [PDF]

Front Neurosci
Sykora M, Harmackova M, Parobkova E, Rusina R, Matěj R.   +4 more
europepmc   +1 more source

Unraveling the conformational landscape of amyloid precursor protein intracellular domain. [PDF]

Biophys J
Mandal N, Skepö M.
europepmc   +1 more source

Age-Rage Signaling pathway which involves Amyloid beta precursor-like protein.

Zhizhong Wang (838758), Sen Xu (111047), Ailong Lin (20917898), Chunxian Wei (22351609), Zhiyong Li (47765), Yingchun Chen (502343), Bizhou Bie (20917901), Ling Liu (143030)   +7 more
openalex   +1 more source