Results 271 to 280 of about 94,035 (378)

The Therapeutic Potential of ADSC-Secreted LEFTY2 in Treating Alzheimer's Disease. [PDF]

open access: yesInt J Mol Sci
Li WW   +8 more
europepmc   +1 more source

Spliceosome protein alterations differentiate hubs of the default mode connectome during the progression of Alzheimer's disease

open access: yesBrain Pathology, EarlyView.
Default mode network (DMN) consists, in part, of the frontal (FC), precuneus (PreC), and posterior cingulate cortex (PCC), which plays a critical role in episodic memory and retrieval of autobiographical memories, displays spatiotemporal differences in the onset of amyloid and hypometabolism that reflects tau neurodegeneration and loss of connectivity ...
Sylvia E. Perez   +8 more
wiley   +1 more source

The Neuroprotective Potential of Betalains: A Focused Review. [PDF]

open access: yesPlants (Basel)
Ştefănescu C   +4 more
europepmc   +1 more source

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

open access: yesBrain Pathology, EarlyView.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie   +9 more
wiley   +1 more source

ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison   +15 more
wiley   +1 more source

Association Between <i>Porphyromonas gingivalis</i> and Alzheimer's Disease: A Comprehensive Review. [PDF]

open access: yesInfect Drug Resist
Sarmiento-Ordóñez JM   +3 more
europepmc   +1 more source

Identification of the Alzheimer beta/A4 amyloid precursor protein in clathrin-coated vesicles purified from PC12 cells.

open access: hybrid, 1993
Christer Nordstedt   +4 more
openalex   +1 more source

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