Results 121 to 130 of about 20,912 (233)

Low Density Lipoprotein Receptor-related Protein (LRP) Interacts with Presenilin 1 and Is a Competitive Substrate of the Amyloid Precursor Protein (APP) for γ-Secretase [PDF]

, 2005
Alberto Lleó, Elaine Waldron, Christine A. F. Von Arnim, Lauren Herl, Michele M. Tangredi, Ithan D. Peltan, Dudley K. Strickland, Edward H. Koo, Bradley T. Hyman, Claus U. Pietrzik, Oksana Berezovska   +10 more
openalex   +1 more source

Androgen Effects on Amyloid Precursor Protein Processing Pathways in Cancer: A Systematic Review. [PDF]

Curr Issues Mol Biol
Alhadrami M, Stone G, Barker RM, Palmer JC, Kehoe PG, Perks CM.   +5 more
europepmc   +1 more source

Investigating the binding potential of the Melissa officinalis oil against Alzheimer's targets by molecular docking and in vitro evaluations. [PDF]

Sci Rep
Kolouei A, Barati M, Abbas-Mohammadi M.
europepmc   +1 more source

γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP)

, 2015
Christian Lessard, Barbara A. Cottrell, Hiroko Maruyama, Suraj Suresh, Todd E. Golde, Edward H. Koo   +5 more
openalex   +2 more sources

Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's β-secretase [PDF]

, 2003
Zoe Scholefield, Edwin A. Yates, Gareth Wayne, Augustin Amour, William McDowell, Jeremy E. Turnbull   +5 more
openalex   +1 more source

FAD Mutations in Presenilin-1 or Amyloid Precursor Protein Decrease the Efficacy of a γ-Secretase Inhibitor: Evidence for Direct Involvement of PS1 in the γ-Secretase Cleavage Complex

, 2000
Weiming Xia, Beth L. Ostaszewski, W. Taylor Kimberly, Talat Rahmati, Chad L. Moore, Michael S. Wolfe, Dennis J. Selkoe   +6 more
openalex   +2 more sources

Mechanistic modeling of amyloid dynamics relating to Alzheimer's disease progression. [PDF]

Front Aging Neurosci
Przekwas A, Norris C, Garimella HT.
europepmc   +1 more source

Membrane-anchored metalloprotease MDC9 has an α-secretase activity responsible for processing the amyloid precursor protein

, 1999
Hisashi Koike, Shigeo Tomioka, Hiroyuki Sorimachi, Takaomi C. Saido, Kei Maruyama, Akira Okuyama, Atsuko Fujisawa‐Sehara, Shigeo Ohno, Koichi Suzuki, Shoichi Ishiura   +9 more
openalex   +2 more sources

Direct and indirect role of non-coding RNAs in company with amyloid and tau protein in promoting neuroinflammation in post-ischemic brain neurodegeneration. [PDF]

Front Cell Neurosci
Pluta R.
europepmc   +1 more source

Protein Kinase C-dependent α-Secretase Competes with β-Secretase for Cleavage of Amyloid-β Precursor Protein in the Trans-Golgi Network [PDF]

, 2000
Daniel Skovronsky, D.Blaine Moore, Marcos E. Milla, Robert W. Doms, Virginia M.‐Y. Lee   +4 more
openalex   +1 more source