Results 121 to 130 of about 31,279 (264)
International Journal of Hypertension, 2012 In rat isolated mesenteric beds that were contracted with NA as an in vitro model of the vascular adrenergic hyperactivity that usually precedes the onset of primary hypertension, the oral administration (3 daily doses) of either 10 mg/kg genistein or 20
Roxana N. Peroni +4 more
doaj +1 more source
Oxyradical Stress, Endocannabinoids, and Atherosclerosis
Toxics, 2015 Atherosclerosis is responsible for most cardiovascular disease (CVD) and is caused by several factors including hypertension, hypercholesterolemia, and chronic inflammation.
Anberitha T. Matthews, Matthew K. Ross
doaj +1 more source
A Brain Motivated to Play: Insights into the Neurobiology of Playfulness
, 2016 Play is an important part of normal childhood development and is seen in varied forms among many mammals. While not indispensable to normal development, playful social experiences as juveniles may provide an opportunity to develop flexible behavioural ...
Siviy, Stephen M.
core +1 more source
Food Science &Nutrition, Volume 14, Issue 4, April 2026.Dietary strategies modulate the progression of diabetic cardiomyopathy by targeting oxidative stress, inflammation, mitochondrial dysfunction, and myocardial fibrosis. Specific nutrients and bioactive compounds, as well as caloric restriction, improve myocardial metabolism and redox balance, whereas ketogenic diets exert time‐dependent beneficial or ...
Wen‐hui Deng +9 more
wiley +1 more source
Journal of Lipid Research, 2016 Vaccenic acid (VA), the predominant ruminant-derived trans fat in the food chain, ameliorates hyperlipidemia, yet mechanisms remain elusive. We investigated whether VA could influence tissue endocannabinoids (ECs) by altering the availability of their ...
Miriam Jacome-Sosa +13 more
doaj +1 more source
A theoretical structure-affinity relationship study of some cannabinoid derivatives [PDF]
, 2008 Indexación: ScieloA ZINDO/1 quantum-chemical structure-affinity relationship study with the KPG model is presented for the in vitro interaction of a group of classical, indole-derived and aminoalkylindole-derived cannabinoids with CB and CB2 receptors ...
Gómez-Jeria, Juan S. +3 more
core +2 more sources
Stress Promotes Drug Seeking Through Glucocorticoid-Dependent Endocannabinoid Mobilization in the Prelimbic Cortex [PDF]
, 2018 Background Clinical reports suggest that rather than directly driving cocaine use, stress may create a biological context within which other triggers for drug use become more potent. We hypothesize that stress-induced increases in corticosterone “set the
Baker, David A. +10 more
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Elevated Brain Cannabinoid CB1 Receptor Availability in Posttraumatic Stress Disorder: A Positron Emission Tomography Study [PDF]
, 2014 Endocannabinoids and their attending cannabinoid type 1 receptor (CB1) have been implicated in animal models of posttraumatic stress disorder (PTSD). However, their specific role has not been studied in people with PTSD.
Bailey, Christopher R. +14 more
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Journal of Lipid Research, 2010 The endocannabinoid metabolome consists of a growing, (patho)physiologically important family of fatty-acid derived signaling lipids. Diet is a major source of fatty acid substrate for mammalian endocannabinoid biosynthesis. The principal long-chain PUFA
JodiAnne T. Wood +5 more
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Endocannabinoid Systetm: Neuropharmacological Implications
Medicine Science, 2016 Marijuana or cannabis has been part of humanity's medicine chest for almost as long as history has been recorded. Cannabinoids are a class of diverse chemical compounds isolated from cannabis that act on cannabinoid receptors (CB1 & CB2).
Vivek Kumar Sharma +3 more
doaj +1 more source