Results 61 to 70 of about 31,279 (264)

Membrane transport of anandamide through resealed human red blood cell membranes

open access: yesJournal of Lipid Research, 2005
The use of resealed red blood cell membranes (ghosts) allows the study of the transport of a compound in a nonmetabolizing system with a biological membrane.
Inge N. Bojesen, Harald S. Hansen
doaj   +1 more source

Behavioral Characterization of the Effects of Cannabis Smoke and Anandamide in Rats

open access: yesPLoS ONE, 2016
Cannabis is the most widely used illicit drug in the world. Delta-9-tetrahydrocannabinol (Δ9-THC) is the main psychoactive component of cannabis and its effects have been well-studied.
Adriaan W. Bruijnzeel   +7 more
semanticscholar   +1 more source

Cannabidiol in Anorexia Nervosa: A Double‐Blind Randomized Placebo Controlled Pilot Study to Test Safety, Pharmacokinetics, and Symptom Change

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota   +8 more
wiley   +1 more source

Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain [PDF]

open access: yes, 2006
Cannabinoid-based medicines have therapeutic potential for the treatment of pain. Augmentation of levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is analgesic in models of acute and inflammatory pain states.
Barrett, David   +4 more
core   +2 more sources

Research Progress on Upper Airway Cough Syndrome

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Central mechanisms mediating the hypophagic effects of oleoylethanolamide and N-acylphosphatidylethanolamines: different lipid signals? [PDF]

open access: yes, 2015
The spread of "obesity epidemic" and the poor efficacy of many anti-obesity therapies in the long-term highlight the need to develop novel efficacious therapy. This necessity stimulates a large research effort to find novel mechanisms controlling feeding
Gaetani, Silvana   +4 more
core   +2 more sources

Comparative effectiveness, safety and acceptability of pharmacological and psychosocial interventions for the treatment of cannabis use disorder: A network meta‐analysis

open access: yesAddiction, EarlyView.
Abstract Aim Our primary aim was to conduct a network meta‐analysis (NMA) for the effectiveness, safety and acceptability of all psychosocial interventions and all pharmacotherapies for cannabis use disorder (CUD). Methods We conducted a NMA of studies identified from two completed systematic reviews examining the effectiveness, safety and ...
Monika Halicka   +6 more
wiley   +1 more source

Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
SignificanceHypoxic pulmonary vasoconstriction (HPV) is an important physiological reflex, which is only found in the lung and adapts perfusion to ventilation. HPV is potentially involved in hypoxia-induced pulmonary hypertension (PH) occurring in respiratory disorders.
Daniela, Wenzel   +6 more
openaire   +2 more sources

Anandamide mitigates ischemia/reperfusion (I/R)-induced gastric ulcer: modulation of inflammation and oxidative stress

open access: yesZagazig Journal of Pharmaceutical Sciences, 2015
Anandamide is a cannabinoid receptors agonist that showed a protective effect against intestinal I/R model. However, its modulatory effect on I/R-induced gastric ulcer has not been previously elucidated.
Shahata H , El-Abhar H , El-Maraghy N
doaj   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

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