Results 81 to 90 of about 31,279 (264)
Molecules, 2021 Fatty acid amides are a diverse family of underappreciated, biologically occurring lipids. Herein, the methods for the chemical synthesis and subsequent characterization of specific members of the fatty acid amide family are described.
Ruidong Ni +7 more
doaj +1 more source
New Synthetic Endocannabinoid as Anti-Inflammaging Cosmetic Active: an In Vitro Study on a Reconstructed Skin Model [PDF]
, 2019 Endocannabinoids have been recently appointed as interesting cosmetic actives in regulating inflammaging, a state of chronic low-grade inflammation, known for being involved in many senescence\u2019s manifestations, included skin aging.
Caviola, E +3 more
core
Corticotropin-Releasing Hormone Drives Anandamide Hydrolysis in the Amygdala to Promote Anxiety
Journal of Neuroscience, 2015 Corticotropin-releasing hormone (CRH) is a central integrator in the brain of endocrine and behavioral stress responses, whereas activation of the endocannabinoid CB1 receptor suppresses these responses.
J. Gray +13 more
semanticscholar +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Frontiers in Pharmacology, 2022 Endocannabinoid transmission is emerging as a target for treating anxiety-related disorders, given its regulation of fear extinction. Boosting anandamide levels via inhibition of its metabolism by fatty acid amide hydrolase (FAAH) can enhance extinction,
William G. Warren +5 more
doaj +1 more source
Phytocannabinoids as novel therapeutic agents in CNS disorders [PDF]
, 2012 The Cannabis sativa herb contains over 100 phytocannabinoid (pCB) compounds and has been used for thousands of years for both recreational and medicinal purposes.
Hill, Andrew J. +3 more
core +1 more source
International Journal of Cancer, Volume 159, Issue 1, Page 257-268, 1 July 2026.What's New? Epithelial ovarian cancer (EOC) is a severe malignancy with few effective treatment options. While the mechanisms remain unclear, changes in lipid metabolism may fuel tumor growth and EOC progression, offering a possible path for new treatments.
Hitomi Sakaguchi‐Mukaida +10 more
wiley +1 more source
Novel, potent THC/anandamide (hybrid) analogs [PDF]
Bioorganic & Medicinal Chemistry, 2007 The structure-activity relationship (SAR) of the end pentyl chain in anandamide (AEA) has been established to be very similar to that of Delta(9)-tetrahydrocannabinol (Delta(9)-THC). In order to broaden our understanding of the structural similarities between AEA and THC, hybrid structures 1-3 were designed.
Caryl, Bourne +6 more
openaire +2 more sources
Journal of Lipid Research, 2015 Arachidonoyl ethanolamine (anandamide) and prostaglandin ethanolamines (prostamides) are biologically active derivatives of arachidonic acid. Although available through different precursor phospholipids, there is considerable overlap between the ...
Paula Urquhart +3 more
doaj +1 more source
Cannabinoid receptor CB2 drives HER2 pro-oncogenic signaling in breast cancer [PDF]
, 2015 Pharmacological activation of cannabinoid receptors elicits antitumoral responses in different models of cancer. However, the biological role of these receptors in tumor physio-pathology is still unknown.
Alkatout, Ibrahim +31 more
core +1 more source