Results 91 to 100 of about 17,707 (220)

Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand [PDF]

open access: yes, 1997
Two endogenous ligands for cannabinoid receptors, anandamide (arachidonylethanolamide) and 2-arachidonoylglycerol, lose their biological activities by enzymatic hydrolysis.
Hiroko Yamaguchi   +7 more
core   +1 more source

Dietary docosahexaenoic acid supplementation alters select physiological endocannabinoid-system metabolites in brain and plasma

open access: yesJournal of Lipid Research, 2010
The endocannabinoid metabolome consists of a growing, (patho)physiologically important family of fatty-acid derived signaling lipids. Diet is a major source of fatty acid substrate for mammalian endocannabinoid biosynthesis. The principal long-chain PUFA
JodiAnne T. Wood   +5 more
doaj   +1 more source

Endocannabinoid Systetm: Neuropharmacological Implications

open access: yesMedicine Science, 2016
Marijuana or cannabis has been part of humanity's medicine chest for almost as long as history has been recorded. Cannabinoids are a class of diverse chemical compounds isolated from cannabis that act on cannabinoid receptors (CB1 & CB2).
Vivek Kumar Sharma   +3 more
doaj   +1 more source

Mechanisms of anandamide‐induced vasorelaxation in rat isolated coronary arteries

open access: yes, 2001
The cannabinoid arachidonyl ethanolamide (anandamide) caused concentration-dependent relaxation of 5-HT-precontracted, myograph-mounted, segments of rat left anterior descending coronary artery.
Bottrill, Fiona E   +9 more
core   +1 more source

Plasma concentrations of endocannabinoids and related primary Fatty Acid amides in patients with post-traumatic stress disorder. [PDF]

open access: yes, 2013
Endocannabinoids (ECs) and related N-acyl-ethanolamides (NAEs) play important roles in stress response regulation, anxiety and traumatic memories. In view of the evidence that circulating EC levels are elevated under acute mild stressful conditions in ...
Kolassa, Iris-Tatjana   +34 more
core   +2 more sources

An Analysis of Endocannabinoid Concentrations and Mood Following Singing and Exercise in Healthy Volunteers

open access: yesFrontiers in Behavioral Neuroscience, 2018
The euphoric feeling described after running is, at least in part, due to increased circulating endocannabinoids (eCBs). eCBs are lipid signaling molecules involved in reward, appetite, mood, memory and neuroprotection.
Nicole L. Stone   +6 more
doaj   +1 more source

Brain activity of anandamide: a rewarding bliss?

open access: yes, 2019
Anandamide is a lipid mediator that acts as an endogenous ligand of CB1 receptors. These receptors are also the primary molecular target responsible for the pharmacological effects of Δ9-tetrahydrocannabinol, the psychoactive ingredient in Cannabis ...
Fratta, Walter   +11 more
core   +1 more source

Antibacterial cathelicidin peptide CAP11 suppresses the anandamide production from lipopolysaccharide-stimulated mononuclear phagocytes [PDF]

open access: yes, 2007
The action of antibacterial cathelicidin peptide CAP11 on the anandamide production from mononuclear phagocytes was examined. Lipopolysaccharide (LPS)-stimulation induced the anandamide production from macrophage-like RAW264.7, accompanied with the ...
Murakami, Taisuke   +5 more
core   +1 more source

Oxygenation of Anandamide by Lipoxygenases [PDF]

open access: yes, 2023
The endocannabinoids anandamide and 2-arachidonoylglycerol are not only metabolized by serine hydrolases, such as fatty acid amide hydrolase, monoacylglycerol lipase, and α,β-hydrolases 6 and 12, but they also serve as substrates for cyclooxygenases ...
van der Stelt, Mario   +1 more
core  

Interaction of anandamide with various lipid monolayers.

open access: yes, 2013
The indicated lipid was spread at the air-water interface to form a compressible monolayer at an initial pressure comprised 20–25 mN.m−1. After stabilization of the monolayer, anandamide was added in the aqueous subphase (final concentration 50 nM ...
Jacques Fantini (367498)   +3 more
core   +1 more source

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