Results 91 to 100 of about 17,707 (220)
Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand [PDF]
Two endogenous ligands for cannabinoid receptors, anandamide (arachidonylethanolamide) and 2-arachidonoylglycerol, lose their biological activities by enzymatic hydrolysis.
Hiroko Yamaguchi +7 more
core +1 more source
The endocannabinoid metabolome consists of a growing, (patho)physiologically important family of fatty-acid derived signaling lipids. Diet is a major source of fatty acid substrate for mammalian endocannabinoid biosynthesis. The principal long-chain PUFA
JodiAnne T. Wood +5 more
doaj +1 more source
Endocannabinoid Systetm: Neuropharmacological Implications
Marijuana or cannabis has been part of humanity's medicine chest for almost as long as history has been recorded. Cannabinoids are a class of diverse chemical compounds isolated from cannabis that act on cannabinoid receptors (CB1 & CB2).
Vivek Kumar Sharma +3 more
doaj +1 more source
Mechanisms of anandamide‐induced vasorelaxation in rat isolated coronary arteries
The cannabinoid arachidonyl ethanolamide (anandamide) caused concentration-dependent relaxation of 5-HT-precontracted, myograph-mounted, segments of rat left anterior descending coronary artery.
Bottrill, Fiona E +9 more
core +1 more source
Plasma concentrations of endocannabinoids and related primary Fatty Acid amides in patients with post-traumatic stress disorder. [PDF]
Endocannabinoids (ECs) and related N-acyl-ethanolamides (NAEs) play important roles in stress response regulation, anxiety and traumatic memories. In view of the evidence that circulating EC levels are elevated under acute mild stressful conditions in ...
Kolassa, Iris-Tatjana +34 more
core +2 more sources
The euphoric feeling described after running is, at least in part, due to increased circulating endocannabinoids (eCBs). eCBs are lipid signaling molecules involved in reward, appetite, mood, memory and neuroprotection.
Nicole L. Stone +6 more
doaj +1 more source
Brain activity of anandamide: a rewarding bliss?
Anandamide is a lipid mediator that acts as an endogenous ligand of CB1 receptors. These receptors are also the primary molecular target responsible for the pharmacological effects of Δ9-tetrahydrocannabinol, the psychoactive ingredient in Cannabis ...
Fratta, Walter +11 more
core +1 more source
Antibacterial cathelicidin peptide CAP11 suppresses the anandamide production from lipopolysaccharide-stimulated mononuclear phagocytes [PDF]
The action of antibacterial cathelicidin peptide CAP11 on the anandamide production from mononuclear phagocytes was examined. Lipopolysaccharide (LPS)-stimulation induced the anandamide production from macrophage-like RAW264.7, accompanied with the ...
Murakami, Taisuke +5 more
core +1 more source
Oxygenation of Anandamide by Lipoxygenases [PDF]
The endocannabinoids anandamide and 2-arachidonoylglycerol are not only metabolized by serine hydrolases, such as fatty acid amide hydrolase, monoacylglycerol lipase, and α,β-hydrolases 6 and 12, but they also serve as substrates for cyclooxygenases ...
van der Stelt, Mario +1 more
core
Interaction of anandamide with various lipid monolayers.
The indicated lipid was spread at the air-water interface to form a compressible monolayer at an initial pressure comprised 20–25 mN.m−1. After stabilization of the monolayer, anandamide was added in the aqueous subphase (final concentration 50 nM ...
Jacques Fantini (367498) +3 more
core +1 more source

