Results 41 to 50 of about 12,113 (164)
Fiyz̤, 2022 Background: Aerobic exercise, ozone therapy and cell therapy have each been independently proposed as treatments for osteoarthritis. Therefore, the present study aimed to investigate the effect of aerobic exercise with ozone and cell therapy on serum ...
Maryam Rezaei +3 more
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Journal of Lipid Research, 2015 Arachidonoyl ethanolamine (anandamide) and prostaglandin ethanolamines (prostamides) are biologically active derivatives of arachidonic acid. Although available through different precursor phospholipids, there is considerable overlap between the ...
Paula Urquhart +3 more
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Two Vanilloid Ligand Bindings Per Channel Are Required to Transduce Capsaicin-Activating Stimuli
Frontiers in Molecular Neuroscience, 2020 The tetrameric capsaicin receptor transient receptor potential vanilloid 1 (TRPV1) in mammals has evolved the capability to integrate pain signal arising from harmful temperature and chemical irritants. The four repetitions of TRPV1 subunits result in an
Ting-Yi Liu +4 more
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Endocannabinoids and related N-acylethanolamines: biological activities and metabolism
Inflammation and Regeneration, 2018 The plant Cannabis sativa contains cannabinoids represented by Δ9-tetrahydrocannabinol, which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2 receptors, respectively, in animal tissues. Arachidonoylethanolamide (also referred to
Kazuhito Tsuboi +3 more
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Tuning the oviduct to the anandamide tone [PDF]
Journal of Clinical Investigation, 2006 Anandamide (N-arachidonoylethanolamide) is a lipid signal molecule that was the first endogenous agonist for cannabinoid receptors to be discovered. Cannabinoid receptor type 1 (CB1) is widely distributed in neurons and nonneuronal cells in brain and peripheral organs including sperm, eggs, and preimplantation embryos. A study by Wang and colleagues in
openaire +2 more sources
Journal of Lipid Research, 2009 The fungal pathogen Candida albicans transforms arachidonic acid (AA) into 3-hydroxyarachidonic acid [3(R)-HETE], and we investigated if its nonpathogenic and 3(R)-HETE-producing close relative, Dipodascopsis uninucleata, could similarly transform the ...
L. De Petrocellis +10 more
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Frontiers in Psychiatry, 2012 Schizophrenia is a complex psychiatric disorder strongly associated with substance use disorders. Theoretically, schizophrenia and SUD may share endocannabinoid alterations in the brain reward system.
Joelle eDesfossés +8 more
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Altered Anandamide Degradation in Attention Deficit Hyperactivity Disorder
Pediatric Neurology Briefs, 2009 Anandamide (AEA) metabolism was investigated in 15 drug-free boys with ADHD (aged 6.5-13 years) and 15 age- and gender-matched healthy controls, in a study at Universita Tor Vergata, Rome, Italy.
J Gordon Millichap
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Pharmacology Research & Perspectives, 2020 Recently, we identified a novel fatty acid amide hydrolase (FAAH) inhibitor, PKM‐833 [(R)‐N‐(pyridazin‐3‐yl)‐4‐(7‐(trifluoromethyl)chroman‐4‐yl)piperazine‐1‐carboxamide].
Toshiya Endo +2 more
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The Endocannabinoid System as a Potential Therapeutic Target for Pain Modulation
Balkan Medical Journal, 2014 Although cannabis has been used for pain management for millennia, very few approved cannabinoids are indicated for the treatment of pain and other medical symptoms. Cannabinoid therapy re-gained attention only after the discovery of endocannabinoids and
Ahmet Ulugöl
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