Results 31 to 40 of about 12,113 (164)

Membrane transport of anandamide through resealed human red blood cell membranes

open access: yesJournal of Lipid Research, 2005
The use of resealed red blood cell membranes (ghosts) allows the study of the transport of a compound in a nonmetabolizing system with a biological membrane.
Inge N. Bojesen, Harald S. Hansen
doaj   +1 more source

Oxygenation of Anandamide by Lipoxygenases

open access: yes, 2016
The endocannabinoids anandamide and 2-arachidonoylglycerol are not only metabolized by serine hydrolases, such as fatty acid amide hydrolase, monoacylglycerol lipase, and α,β-hydrolases 6 and 12, but they also serve as substrates for cyclooxygenases, cytochrome P450s, and lipoxygenases.
Zadelhoff, G. van, Stelt, M. van der
openaire   +6 more sources

Cannabinoid Receptor Activation Disrupts the Internal Structure of Hippocampal Sharp Wave–Ripple Complexes

open access: yesJournal of Pharmacological Sciences, 2012
Cannabinoid agonists impair hippocampus-dependent learning and memory. Using mouse hippocampal slice preparations, we examined the effect of anandamide, an endogenous cannabinoid, on sharp wave–ripple (SW-R) complexes, which are believed to mediate ...
Yi Sun   +4 more
doaj   +1 more source

N-acylethanolamines, anandamide and food intake [PDF]

open access: yesBiochemical Pharmacology, 2009
Anandamide and the other N-acylethanolamines, e.g. oleoylethanolamide (OEA), palmitoylethanolamide (PEA), and linoleoylethanolamide (LEA), may be formed by several enzymatic pathways from their precursors, which are the N-acylated ethanolamine phospholipids.
Hansen, Harald S, Diep, Thi Ai
openaire   +4 more sources

Anandamide mitigates ischemia/reperfusion (I/R)-induced gastric ulcer: modulation of inflammation and oxidative stress

open access: yesZagazig Journal of Pharmaceutical Sciences, 2015
Anandamide is a cannabinoid receptors agonist that showed a protective effect against intestinal I/R model. However, its modulatory effect on I/R-induced gastric ulcer has not been previously elucidated.
Shahata H , El-Abhar H , El-Maraghy N
doaj   +1 more source

Endocannabinoid System in Pregnancy Maintenance and Labor: A Mini-Review

open access: yesFrontiers in Endocrinology, 2021
The endocannabinoid system (ECS) is a cell-signaling system present in multiple organ systems and is an integral part of sustaining the microenvironment necessary for early pregnancy success and maintenance.
Melissa L. Kozakiewicz   +2 more
doaj   +1 more source

Inhibition of synaptic transmission by anandamide precursor 20:4-NAPE is mediated by TRPV1 receptors under inflammatory conditions

open access: yesFrontiers in Molecular Neuroscience, 2023
Transient receptor potential ion channel, vanilloid subfamily, type 1 (TRPV1) cation channel, and cannabinoid receptor 1 (CB1) are essential in the modulation of nociceptive signaling in the spinal cord dorsal horn that underlies different pathological ...
Diana Spicarova   +7 more
doaj   +1 more source

Synthesis, Quantification, and Characterization of Fatty Acid Amides from In Vitro and In Vivo Sources

open access: yesMolecules, 2021
Fatty acid amides are a diverse family of underappreciated, biologically occurring lipids. Herein, the methods for the chemical synthesis and subsequent characterization of specific members of the fatty acid amide family are described.
Ruidong Ni   +7 more
doaj   +1 more source

A Personal Retrospective: Elevating Anandamide (AEA) by Targeting Fatty Acid Amide Hydrolase (FAAH) and the Fatty Acid Binding Proteins (FABPs)

open access: yesFrontiers in Pharmacology, 2016
This perspective was adapted from a Career Achievement Award talk given at the International Cannabinoid Research Society Symposium in Bukovina, Poland on June 27, 2016.
Dale Deutsch
doaj   +1 more source

Endocannabinoid metabolism inhibition has no effect on spontaneous fear recovery or extinction resistance in Lister hooded rats

open access: yesFrontiers in Pharmacology, 2022
Endocannabinoid transmission is emerging as a target for treating anxiety-related disorders, given its regulation of fear extinction. Boosting anandamide levels via inhibition of its metabolism by fatty acid amide hydrolase (FAAH) can enhance extinction,
William G. Warren   +5 more
doaj   +1 more source

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