The Effects of the Endocannabinoids Anandamide and 2-Arachidonoylglycerol on Human Osteoblast Proliferation and Differentiation. [PDF]
PLoS ONE, 2015 The endocannabinoid system is expressed in bone, although its role in the regulation of bone growth is controversial. Many studies have examined the effect of endocannabinoids directly on osteoclast function, but few have examined their role in human ...
Marie Smith +5 more
doaj +1 more source
Enhanced Anandamide Plasma Levels in Patients with Complex Regional Pain Syndrome following Traumatic Injury: A Preliminary Report [PDF]
, 2009 The complex regional pain syndrome (CRPS) is a disabling neuropathic pain condition that may develop following injuries of the extremities. The pathogenesis of this syndrome is not clear; however, it includes complex interactions between the nervous and ...
Campolongo, P. +7 more
core +1 more source
British Journal of Pharmacology, 2018 Autism spectrum disorder (ASD) is more commonly diagnosed in males than in females. Prenatal exposure to the antiepileptic drug valproic acid (VPA) is an environmental risk factor of ASD.
F. Melancia +7 more
semanticscholar +1 more source
Plasma anandamide and other N-acylethanolamines are correlated with their corresponding free fatty acid levels under both fasting and non-fasting conditions in women [PDF]
, 2010 N-acylethanolamines (NAEs), such as anandamide (AEA), are a group of endogenous lipids derived from a fatty acid linked to ethanolamine and have a wide range of biological activities, including regulation of metabolism and food intake.
Balvers, M.G.J. +4 more
core +2 more sources
Metabolism of the Endocannabinoid Anandamide: Open Questions after 25 Years
Frontiers in Molecular Neuroscience, 2017 Cannabis extracts have been used for centuries, but its main active principle ∆9-tetrahydrocannabinol (THC) was identified about 50 years ago. Yet, it is only 25 years ago that the first endogenous ligand of the same receptors engaged by the cannabis ...
M. Maccarrone
semanticscholar +1 more source
Effect of an unstirred layer on the membrane permeability of anandamide
Journal of Lipid Research, 2006 To study the effect of an unstirred layer (UL), we have investigated the exchange efflux kinetics of anandamide at 0°C, pH 7.3, from albumin-free as well as from albumin-filled human red blood cell ghosts to media of various BSA concentrations ([BSA]o ...
Inge N. Bojesen, Harald S. Hansen
doaj +1 more source
Effects of parabolic flight and spaceflight on the endocannabinoid system in humans [PDF]
, 2012 The endocannabinoid system (ECS) plays an important role in the regulation of physiological functions, from stress and memory regulation to vegetative control and immunity.
Chouker, Alexander +7 more
core +1 more source
Translational Psychiatry, 2023 Cannabidiol (CBD) has shown promise in treating psychiatric disorders, including cannabis use disorder – a major public health burden with no approved pharmacotherapies. However, the mechanisms through which CBD acts are poorly understood.
Daniel Ying-Heng Hua +8 more
doaj +1 more source
The therapeutic aspects of the endocannabinoid system (ECS) for cancer and their development: from nature to laboratory [PDF]
, 2016 The endocannabinoid system (ECS) is a group of neuromodulatory lipids and their receptors, which are widely distributed in mammalian tissues. ECS regulates various cardiovascular, nervous, and immune system functions inside cells.
Botta, Bruno +5 more
core +1 more source
Plasma concentrations of endocannabinoids and related primary Fatty Acid amides in patients with post-traumatic stress disorder. [PDF]
, 2013 Endocannabinoids (ECs) and related N-acyl-ethanolamides (NAEs) play important roles in stress response regulation, anxiety and traumatic memories. In view of the evidence that circulating EC levels are elevated under acute mild stressful conditions in ...
Atsak, Piray +10 more
core +6 more sources