Results 31 to 40 of about 17,707 (220)

Peripheral Endogenous Cannabinoid Levels Are Increased in Schizophrenia Patients Evaluated in a Psychiatric Emergency Setting

Frontiers in Psychiatry, 2020
BackgroundThe endogenous cannabinoid system mediates the psychoactive effects of cannabis in the brain. It has been argued that this system may play a key role in the pathophysiology of schizophrenia.
Stéphane Potvin, Stéphane Potvin, Louiza Mahrouche, Roxane Assaf, Roxane Assaf, Marjolaine Chicoine, Charles-Édouard Giguère, Alexandra Furtos, Roger Godbout, Roger Godbout   +9 more
doaj   +1 more source

Traumatic Stress, Chronic Ethanol Exposure, or the Combination, Alter Cannabinoid System Components in Reward and Limbic Regions of the Mouse Brain

Molecules, 2021
The cannabinoid system is independently affected by stress and chronic ethanol exposure. However, the extent to which co-occurrence of traumatic stress and chronic ethanol exposure modulates the cannabinoid system remains unclear.
Veronica M. Piggott, Scott C. Lloyd, James I. Matchynski, Shane A. Perrine, Alana C. Conti   +4 more
doaj   +1 more source

Time-Dependent Vascular Effects of Endocannabinoids Mediated by Peroxisome Proliferator-Activated Receptor Gamma (PPAR𝛾)

PPAR Research, 2009
The aim of the present study was to examine whether endocannabinoids cause PPAR𝛾-mediated vascular actions. Functional vascular studies were carried out in rat aortae. Anandamide and N-arachidonoyl-dopamine (NADA), but not palmitoylethanolamide, caused
Saoirse E. O'Sullivan, David A. Kendall, Michael D. Randall   +2 more
doaj   +1 more source

Effects of parabolic flight and spaceflight on the endocannabinoid system in humans [PDF]

, 2012
The endocannabinoid system (ECS) plays an important role in the regulation of physiological functions, from stress and memory regulation to vegetative control and immunity.
Feuerecker, Matthias, Strewe, Claudia, Schelling, Gustav, Morukov, Boris, Chouker, Alexander, Nichiporuk, Igor, Kaufmann, Ines, Hauer, Daniela   +7 more
core   +1 more source

Inhibition by Anandamide of 6-Hydroxydopamine-Induced Cell Death in PC12 Cells

International Journal of Cell Biology, 2010
6-hydroxydopamine (6-OHDA) is a selective neurotoxin that is widely used to investigate cell death and protective strategies in models of Parkinson's disease.
Katarzyna Mnich, David P. Finn, Eilis Dowd, Adrienne M. Gorman   +3 more
doaj   +1 more source

Anandamide Induces Endothelium-Dependent Vasoconstriction and CGRPergic Nerve–Mediated Vasodilatation in the Rat Mesenteric Vascular Bed

Journal of Pharmacological Sciences, 2012
An endogenous cannabinoid anandamide (N-arachidonoylethanolamide) has been shown to cause vasodilatation in vitro and a brief vasoconstriction followed by prolonged depressor response in vivo.
Chihiro Tamaki, Hideki Nawa, Shingo Takatori, Sakiko Oda, Toshiaki Sendo, Yoshito Zamami, Hiromu Kawasaki   +6 more
doaj   +1 more source

Pitfalls and solutions in assaying anandamide transport in cells[S]

Journal of Lipid Research, 2010
Nonspecific binding of anandamide to plastic exhibits many features that could be mistaken as biological processes, thereby representing an important source of conflicting data on the uptake and release of this lipophilic substance. Herein, we propose an
Sergio Oddi, Filomena Fezza, Giuseppina Catanzaro, Chiara De Simone, Mariangela Pucci, Daniele Piomelli, Alessandro Finazzi-Agrò, Mauro Maccarrone   +7 more
doaj   +1 more source

Changes of endocannabinoid plasma levels following type I trauma [PDF]

, 2012
The endocannabinoid system has emerged as one of the most important facilitators of stress adaptation in the body. So far, little to no research took place concerning the endocannabinoid response to stress in humans.
Heimendahl, Jenny von
core   +1 more source

Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests

Brazilian Journal of Medical and Biological Research, 2009
The endocannabinoid system is involved in the control of many physiological functions, including the control of emotional states. In rodents, previous exposure to an open field increases the anxiety-like behavior in the elevated plus-maze.
A. Ribeiro, V. Ferraz-de-Paula, M.L. Pinheiro, J. Palermo-Neto   +3 more
doaj   +1 more source

Effect of Anandamide on Erythrocyte Survival [PDF]

Cellular Physiology and Biochemistry, 2007
The endocannabinoid anandamide (Arachidonylethanolamide, AEA) is known to induce apoptosis in a wide variety of nucleated cells. The present study explored whether anandamide induces suicidal death of erythrocytes or eryptosis, which is characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine exposure at the erythrocyte ...
Peter J, Bentzen, Florian, Lang
openaire   +2 more sources