Results 161 to 170 of about 7,941 (204)

The anaphylatoxin-forming system

Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie, 1967
Introduct ion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . t 60 I. Format ion of anaphylatoxin. Evidence for an enzymic mechanism . . . . . t 62 II . The components of the anaphyla toxin system . . . . . . . . . . . . . . . 165 A. The anaphylatoxin-forming enzymes . . . . . . . . . . . . . . . . . 165 1. The cobra enzyme . . . . . . . .
openaire   +2 more sources

Formation of anaphylatoxin in human serum

Experientia, 1969
Es ist moglich, auch in menschlichem Serum eine Anaphylatoxinbildung (AT) durch Kontaktaktivierung oder Kobragift zu induzieren. Wegen der geringen Mengen, die entstehen, muss das wirksame Prinzip vor dem biologischen Nachweis angereichert werden. Menschliches AT verhalt sich in allen untersuchten Eigenschaften wie AT aus anderen Plasmaarten.
W, Vogt, G, Bodammer, E, Lufft, G, Schmidt   +3 more
openaire   +2 more sources

Granzyme K activates the entire complement cascade

Nature
Granzymes are a family of serine proteases that are mainly expressed by CD8+ T cells, natural killer cells and innate-like lymphocytes1. Although their primary function is thought to be the induction of cell death in virally infected cells and tumours ...
Carlos A Donado, Erin Theisen, Fan Zhang, A. Nathan, M.L. Fairfield, K. Rupani, Dominique Jones, Kellsey P. A. Johannes, J. Albrecht, J. Anolik, W. Apruzzese, J. Barnas, J. Bathon, A. Ben-Artzi, Brendan F Boyce, David L. Boyle, S. Bridges, Vivian P. Bykerk, Debbie Campbell, Arnoldas Ceponis, A. Chicoine, Michelle Curtis, K. Deane, E. DiCarlo, L. Donlin, P. Dunn, Andrew Filer, Hayley L. Carr, Garry S. Firestein, Lindsy J. Forbess, L. Geraldino‐Pardilla, Susan M. Goodman, Ellen M. Gravallese, Deepak A. Rao, Peter K. Gregersen, J. Guthridge, M. Gutiérrez-Arcelus, V. Holers, D. Horowitz, Laura B. Hughes, Lionel B. Ivashkiv, K. Ishigaki, J. James, Joyce B. Kang, Gregory Keras, Amit Lakhanpal, James A. Lederer, Miles J. Lewis, Yuhong Li, Katherine P. Liao, A. Mandelin, I. Mantel, K. Marks, M. Maybury, A. McDavid, M. McGeachy, Joseph R. Mears, N. Meednu, N. Millard, L. Moreland, S. Nayar, A. Nerviani, Dana E. Orange, H. Perlman, Costantino Pitzalis, J. Rangel-Moreno, Karim Raza, Yakir A. Reshef, Christopher T Ritchlin, F. Rivellese, William H Robinson, Laurie Rumker, I. Sahbudin, S. Sakaue, Jennifer A Seifert, D. Scheel-Toellner, A. Singaraju, Kamil Slowikowski, Melanie H. Smith, Darren Tabechian, P. Utz, Kathryn Weinand, Dana Weisenfeld, Michael H. Weisman, Qian Xiao, Zhu Zhu, Zhihan J. Li, Andrew Cordle, Aaron Wyse, Soumya Raychaudhuri, Daniel F. Dwyer, A. Jonsson, Michael B. Brenner   +92 more
semanticscholar   +1 more source

Anaphylatoxin Formation in Extracorporeal Circuits

Complement, 2017
Anaphylatoxin radioimmunoassay techniques have been employed to define both the temporal profile and the amount of complement activation taking place in two different types of extracorporeal circuits. Prospective studies of patients undergoing both maintenance hemodialysis and cardiopulmonary bypass provided essentially similar findings. In both cases,
openaire   +2 more sources

Modulation of the Immune Response by Anaphylatoxins

Complement, 2017
Bioactive C3a and C5a fragments derived from the human complement compounds C3 and C5, respectively, possess immunoregulatory activities. C3a and C5a differentially influence in vitro immune function. C3a was found to be a potent suppressor of antigenspecific and polyclonal antibody responses.
openaire   +2 more sources

Regulation and function of anaphylatoxins and their receptors in allergic asthma.

Molecular Immunology, 2017
Y. Laumonnier, Anna V. Wiese, Julia Figge, C. Karsten   +3 more
semanticscholar   +1 more source

Structure and Function of C3a Anaphylatoxin*

1990
The C3a molecule is one of three activation fragments from the complement cascade, a family of factors that include C3a, C4a, and C5a. Early recognition that more than one bio active fragment was generated during complement activation cascade must be credited to COCHRANE and MULLER-EBERHARD (1968) and to DIAS DA SILVA et al. (1967). These investigators
openaire   +2 more sources

Effects of Bothrops atrox venom and two isolated toxins on the human complement system: Modulation of pathways and generation of anaphylatoxins.

Molecular Immunology, 2016
Danilo L Menaldo, C. Bernardes, A. L. Jacob-Ferreira, C. Nogueira-Santos, T. M. Casare-Ogasawara, L. S. Pereira-Crott, S. Sampaio   +6 more
semanticscholar   +1 more source

Complement activation during cardiopulmonary bypass: evidence for generation of C3a and C5a anaphylatoxins.

New England Journal of Medicine, 1981
D. Chenoweth, S. W. Cooper, T. Hugli, R. Stewart, E. Blackstone, J. Kirklin   +5 more
semanticscholar   +1 more source

On Anaphylatoxin

International Archives of Allergy and Applied Immunology, 2009
openaire   +2 more sources