Results 151 to 160 of about 5,613 (194)
Some of the next articles are maybe not open access.
Anaphylatoxin Formation in Sepsis
Archives of Surgery, 1988Complement activation and anaphylatoxin formation were studied in 27 septic patients. The patients were treated with antibiotics and high-dose corticosteroids. Blood samples were drawn on admission and every week thereafter. Plasma levels of complement components C1INH, C3, C4, and C5 were low before the start of treatment but were above normal one ...
A, Bengtson, M, Heideman
openaire +2 more sources
Histamine Release by Anaphylatoxin
Nature, 1951EARLY studies of the mechanism of anaphylaxis led to two apparently contradictory views : the so-called ‘humoral theory’, according to which the blood is the site of production of a toxin, the anaphylatoxin1–4; and the ‘cellular theory’, which localizes the anaphylactic reaction in the cells, and assumes that this reaction causes the release of ...
M, ROCHA E SILVA, O, BIER, M, ARONSON
openaire +2 more sources
1978
Publisher Summary This chapter discusses the structural and functional characterization of anaphylatoxins, spasmogenic substances released during complement activation. These low molecular weight peptide fragments of C3 and C5 elicit a variety of cellular responses, which implies that they play a significant role in inflammation and acute allergic ...
T E, Hugli, H J, Müller-Eberhard
openaire +2 more sources
Publisher Summary This chapter discusses the structural and functional characterization of anaphylatoxins, spasmogenic substances released during complement activation. These low molecular weight peptide fragments of C3 and C5 elicit a variety of cellular responses, which implies that they play a significant role in inflammation and acute allergic ...
T E, Hugli, H J, Müller-Eberhard
openaire +2 more sources
Anaphylatoxin and Anaphylaxis: XI. Ultra-Filtration and Fractionation of Anaphylatoxin
Journal of Infectious Diseases, 1919Despite the large amount of study on the nature of anaphylatoxin and of the mechanism of its formation, little if any attempt has been made to isolate the toxic principle on one or the other of the protein fractions of the serum. Various serum principles having physiologic activity, but of unknown chemical nature, have been isolated on the protein ...
P. H. De Kruif, A. H. Eggerth
openaire +1 more source
Journal of the American Medical Association, 1924
In previous papers it was shown that characteristic anaphylactic contractions of the urinary bladder 1 and of the gastro-intestinal tract 2 do not take place in dehepatized anaphylactic dogs. The conclusion was drawn that the typical anaphylactic contractions of these organs are due to chemical products (hepatic anaphylatoxins) explosively formed or ...
W. H. MANWARING +3 more
openaire +1 more source
In previous papers it was shown that characteristic anaphylactic contractions of the urinary bladder 1 and of the gastro-intestinal tract 2 do not take place in dehepatized anaphylactic dogs. The conclusion was drawn that the typical anaphylactic contractions of these organs are due to chemical products (hepatic anaphylatoxins) explosively formed or ...
W. H. MANWARING +3 more
openaire +1 more source
Osteoarthritis and CartilageObjective The complement cascade as major fluid phase innate immune system is activated during progression of osteoarthritis (OA). Generated anaphylatoxins and the corresponding receptors C3aR and C5aR1 are associated with the calcification of blood ...
Gundula Schulze-Tanzil +2 more
exaly +2 more sources
Journal of the American Medical Association, 1924
The liver is the first organ for which a function of internal secretion was predicted by Claude Bernard. Our knowledge of hepatic physiology is so scanty, however, that modern textbooks on endocrinology rarely mention the liver as a possible site of hormone formation.
W. H. MANWARING +3 more
openaire +1 more source
The liver is the first organ for which a function of internal secretion was predicted by Claude Bernard. Our knowledge of hepatic physiology is so scanty, however, that modern textbooks on endocrinology rarely mention the liver as a possible site of hormone formation.
W. H. MANWARING +3 more
openaire +1 more source
Biochemistry and Biology of Anaphylatoxins
Complement, 2017The molecular architecture of anaphylatoxins has been explored on several levels. Primary, secondary and tertiary structural parameters that dictate function of the C3a, C4a and C5a molecules are being elucidated with the aid of comparative sequence analyses, physical measurements and organic syntheses.
openaire +2 more sources
The anaphylatoxin-forming system
Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie, 1967Introduct ion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . t 60 I. Format ion of anaphylatoxin. Evidence for an enzymic mechanism . . . . . t 62 II . The components of the anaphyla toxin system . . . . . . . . . . . . . . . 165 A. The anaphylatoxin-forming enzymes . . . . . . . . . . . . . . . . . 165 1. The cobra enzyme . . . . . . . .
openaire +2 more sources
Formation of anaphylatoxin in human serum
Experientia, 1969Es ist moglich, auch in menschlichem Serum eine Anaphylatoxinbildung (AT) durch Kontaktaktivierung oder Kobragift zu induzieren. Wegen der geringen Mengen, die entstehen, muss das wirksame Prinzip vor dem biologischen Nachweis angereichert werden. Menschliches AT verhalt sich in allen untersuchten Eigenschaften wie AT aus anderen Plasmaarten.
W, Vogt +3 more
openaire +2 more sources