Results 11 to 20 of about 7,941 (204)
Complement anaphylatoxins: Potential therapeutic target for diabetic kidney disease [PDF]
Diabetic MedicineDiabetic kidney disease (DKD) is the most common cause of kidney failure, characterized by chronic inflammation and fibrosis. The complement system is increasingly implicated in the development and progression of diabetic nephropathy.
Ma J, Yiu WH, Tang SCW.
exaly +3 more sources
Interleukin-33 Amplifies Human Mast Cell Activities Induced by Complement Anaphylatoxins
Frontiers in Immunology, 2021 Both, aberrant mast cell responses and complement activation contribute to allergic diseases. Since mast cells are highly responsive to C3a and C5a, while Interleukin-33 (IL-33) is a potent mast cell activator, we hypothesized that IL-33 critically ...
Peter W. West +8 more
doaj +2 more sources
Interleukin-1β and anaphylatoxins exert a synergistic effect on NGF expression by astrocytes
Journal of Neuroinflammation, 2006 C3a and C5a anaphylatoxins are proinflammatory polypeptides released during complement activation. They exert their biological activities through interaction with two G protein-coupled receptors named C3aR and C5aR, respectively.
Patte Christine +8 more
doaj +2 more sources
BMC Immunology, 2012 Background The genus Micrurus, coral snakes (Serpentes, Elapidae), comprises more than 120 species and subspecies distributed from the south United States to the south of South America. Micrurus snake bites can cause death by muscle paralysis and further
Tanaka Gabriela D +4 more
doaj +2 more sources
Role of the Complement System in the Modulation of T-Cell Responses in Chronic Chagas Disease
Frontiers in Cellular and Infection Microbiology, 2022 Chagas disease, caused by the intracellular pathogen Trypanosoma cruzi, is the parasitic disease with the greatest impact in Latin America and the most common cause of infectious myocarditis in the world.
María Belén Caputo +6 more
doaj +1 more source
Anaphylatoxin and Anaphylaxis: I. Trypanosome Anaphylatoxin [PDF]
Journal of Infectious Diseases, 1917 FOREWORD METHODS EMPLOYED AttAPHYLATOXIN-PRODUCTION WITH : SURRA TRYPANOSOME (T. EVAN SI) CADERAS TRYPANOSOME (t. EQUINUM) DOURINE TRYPANOSOME (T. EQUIPERDUM) TRYPANOSOMA LEWISI SERIAL PRODUCTION NAGANA TRYPANOSOME (t. BRUCEl) GUINEA-PIG SERUM ; SERIAL PRODUCTION J TOXIC WAVE.
Novy, F. G., DeKruif, P. H., Novy, R. L.
openaire +1 more source
Complement activation during cardiopulmonary bypass and association with clinical outcomes
eJHaem, 2022 In this prospective, single‐centre observational study of 30 patients undergoing cardiopulmonary bypass (CPB), the effect of unfractionated heparin (UFH), CPB surgery and protamine sulphate on complement and on post‐operative blood loss were assessed ...
Rengina Kefalogianni +7 more
doaj +1 more source
ColdZyme Maintains Integrity in SARS-CoV-2-Infected Airway Epithelia
mBio, 2021 SARS-CoV-2 infection causing the COVID-19 pandemic calls for immediate interventions to avoid viral transmission, disease progression, and subsequent excessive inflammation and tissue destruction. Primary normal human bronchial epithelial cells are among
W. Posch +7 more
doaj +1 more source
Vaccines, 2023 The underlying immunological mechanisms of immediate-type hypersensitivity reactions (HSR) to COVID-19 vaccines are poorly understood. We investigate the mechanisms of immediate-type hypersensitivity reactions to the Pfizer BNT162b2 vaccine and the ...
Xin Rong Lim +13 more
doaj +1 more source
Anaphylatoxin and Anaphylaxis: VII. Peptone Anaphylatoxin [PDF]
Journal of Infectious Diseases, 1917 n ...
Novy, F. G., DeKruif, P. H., Novy, F. O.
openaire +2 more sources