Results 1 to 10 of about 114,599 (253)
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BioEssays, 2004
AbstractAndrogens (testosterone), acting via the androgen receptor (AR) a nuclear transcription factor, regulate male sexual development and body composition. In addition, AR expression plays an important role in the proliferation of human prostate cancer and confers a better prognosis in breast cancer. AR mRNA stability is central to the regulation of
Bu B, Yeap +2 more
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AbstractAndrogens (testosterone), acting via the androgen receptor (AR) a nuclear transcription factor, regulate male sexual development and body composition. In addition, AR expression plays an important role in the proliferation of human prostate cancer and confers a better prognosis in breast cancer. AR mRNA stability is central to the regulation of
Bu B, Yeap +2 more
openaire +2 more sources
Targeting the Androgen Receptor
Urologic Clinics of North America, 2012Androgen receptor (AR)-mediated signaling is critical to the growth and survival of prostate cancer. Although medical castration and antiandrogen therapy can decrease AR activity and lower PSA, castration resistance eventually develops. Recent work exploring the molecular structure and evolution of AR in response to hormonal therapies has revealed ...
Terence W, Friedlander, Charles J, Ryan
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Murine Thymic Androgen Receptors
Journal of Immunopharmacology, 1980Studies in mice indicate that sex hormones influence the immune system. In general females are more immunocompetent than males and the administration of androgens can suppress antibody formation in females. New Zealand Black (NZB) mice manifest a lack of sex difference in the production of certain autoantibodies and the failure of androgen ...
E S, Raveche +3 more
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Androgen Receptor: An Overview
Critical Reviews™ in Eukaryotic Gene Expression, 1995The action of androgens in regulating development and growth is mediated by androgen receptor (AR). AR is a member of the steroid hormone receptor superfamily, a class of receptors that function through their ability to regulate the transcription of specific genes.
C, Chang +7 more
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Androgens, Androgen Receptor, and Bone
2020Silvia Colucci, Giacomina Brunetti
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