Results 11 to 20 of about 117,825 (166)
Pakistan Armed Forces Medical Journal, 2021 Objective: To determine the frequency of immunohistochemical expression of androgen receptor in triple negative breast carcinoma. Study Design: Cross sectional study.
Amna Ameer +3 more
doaj +3 more sources
Androgen Receptor Phosphorylation [PDF]
Endocrine Research, 1993 Phosphorylation of transcription factors plays an important role in regulation of gene expression. DNA-binding, transactivation activity, and subcellular trafficking of specific transcription factors have been shown to be regulated by phosphorylation/dephosphorylation.
L J, Blok +2 more
openaire +3 more sources
Genetics Research, 2023 Objective. The purpose of our work was to explore the association of mutations in the androgen receptor gene and copy numbers of the androgen-receptor silk protein A complex with glutathione-S-transferases T1 and M1 in prostate cancer patients. Materials
Yan Zhang +4 more
doaj +1 more source
Androgen receptors in meningiomas [PDF]
Cancer, 1988 Meningiomas have been hypothesized as being hormonally sensitive on the basis of epidemiologic, clinical, and laboratory evidence. Eight meningiomas were assayed and found to have androgen-binding protein. Three tumors were subjected to in vitro growth studies in varying concentrations of dihydrotestosterone (DHT).
J J, Olson +3 more
openaire +2 more sources
Dissecting the roles of the androgen receptor in prostate cancer from molecular perspectives
Tumor Biology, 2017 Androgen receptor plays a pivotal role in prostate cancer progression, and androgen deprivation therapy to intercept androgen receptor signal pathway is an indispensable treatment for most advanced prostate cancer patients to delay cancer progression ...
Jieping Hu, Gongxian Wang, Ting Sun
doaj +1 more source
BMC Research Notes, 2018 Objectives Recent evidence suggests a role of androgen receptor expression as a prognostic and therapeutic biomarker in endometrial carcinoma, therefore in the present study we aimed to evaluate the frequency of androgen expression in different subtypes ...
Atif Ali Hashmi +7 more
doaj +1 more source
Androgen Receptor Signaling in the Development of Castration-Resistant Prostate Cancer
Frontiers in Oncology, 2019 Most prostate cancers are androgen-sensitive malignancies whose growths depend on the transcriptional activity of the androgen receptor (AR). In the 1940s, Charles Huggins demonstrated that the surgical removal of testes in men can result in a dramatic ...
Qin Feng, Bin He, Bin He
doaj +1 more source
Prognostic Value of Androgen Receptor Expression in Bladder Tumors [PDF]
Translational Research in Urology, 2023 Introduction: The present study was conducted with the aim of investigating the prognostic value of androgen receptor expression in bladder tumors.Methods: This study was conducted in the urology department of Imam Reza Hospital on male patients with ...
Salman Soltani +8 more
doaj +1 more source
NON-GENOMIC ANDROGEN ACTION REGULATES PROLIFERATIVE/MIGRATORY SIGNALLING IN STROMAL CELLS.
Frontiers in Endocrinology, 2015 Prostate cancer is the major cause of cancer-related death among the male population of Western society, and androgen deprivation therapy represents the first line in prostate cancer treatment. However, although androgen receptor expression is maintained
Marzia eDi Donato +9 more
doaj +1 more source
Androgen Receptor and Mechanism of Androgen Action
Annals of Medicine, 1993 Androgen receptor is the intracellular protein that mediates biological actions of physiological androgens (testosterone and 5 alpha-dihydrotestosterone). Androgen receptor belongs to a large family of ligand-dependent proteins whose function is to modulate expression of genes and gene networks in a cell- and tissue-specific manner.
O A, Jänne +3 more
openaire +2 more sources