Results 11 to 20 of about 71,539 (153)

Partial Androgen Insensitivity Syndrome Presenting with Gynecomastia [PDF]

open access: yesEndocrinology and Metabolism, 2015
Gynecomastia is a benign enlargement of the male breast caused by the proliferation of glandular breast tissue. Determining the various causes of gynecomastia such as physiological causes, drugs, systemic diseases, and endocrine disorders is important ...
Sung Won Lee   +10 more
doaj   +1 more source

Overexpression of Androgen, Oestrogen and Progesterone Receptors in Skin Lesions of Becker’s Naevus

open access: yesActa Dermato-Venereologica, 2018
Becker’s naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder.
Ping Sheng   +6 more
doaj   +1 more source

Immunohistochemical features of ovarian structure at polycystic ovary syndrom depending on the age

open access: yesPatologìâ, 2012
peculiarities of proliferation factors and androgens receptors expression in women with PCOS, depending on age were analyzed. It was revealed that pronounced expression of PCNA, cytokeratin and androgen receptors in stroma and intengification of PCNA ...
I. Yu. Ganzhiy
doaj   +1 more source

A computational insight into endocrine disruption by polychlorinated biphenyls via non-covalent interactions with human nuclear receptors

open access: yesEcotoxicology and Environmental Safety, 2021
Production of polychlorinated biphenyls (PCBs) was banned a long time ago because of their harmful health effects but humans continue to be exposed to residual PCBs in the environment.
Lukman K. Akinola   +3 more
doaj   +1 more source

Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells

open access: yesMolecular Cancer, 2008
Background Recently we have reported membrane androgen receptors-induced apoptotic regression of prostate cancer cells regulated by Rho/ROCK/actin signaling.
Gravanis Achilleas   +8 more
doaj   +1 more source

DRUG THERAPY FOR ANDROGEN-POSITIVE BREAST CANCER

open access: yesСибирский онкологический журнал, 2021
There are some types of breast cancer (BC) that depend on their molecular characteristics. However, lately researchers provide date regarding the presence of additional receptors of triple negative breast cancer (TNBC).
A. D. Zikiryakhodjhaev   +4 more
doaj   +1 more source

The multiple actions of testosterone in men: nature knows best

open access: yesAsian Journal of Andrology, 2014
In male hormone replacement therapy Finkelstein et al. show that testosterone rather than synthetic "pure" androgens should be prescribed. Testosterone is converted to the superactive androgen dihydrotestosterone and to estradiol, and thus has actions ...
John W Funder
doaj   +1 more source

Adiponectin and its receptors in the ovary: further evidence for a link between obesity and hyperandrogenism in polycystic ovary syndrome. [PDF]

open access: yesPLoS ONE, 2013
Polycystic ovary syndrome (PCOS), characterized by ovarian androgen excess, is the commonest endocrine disorder in women. Obesity increases androgen synthesis, a phenomenon attributed to the accompanying hyperinsulinemia.
Fabio V Comim   +2 more
doaj   +1 more source

Androgen receptor epigenetics.

open access: yesTranslational andrology and urology, 2013
The androgen receptor (AR) is a transcription factor that drives the differentiation of prostate epithelium by regulating the expression of several hundred genes. Conversely, AR also plays a central role in prostate cancer (PCa) development, and it continues to be active in tumors that relapse after castration (castration-resistant prostate cancer ...
Cai, Changmeng   +2 more
openaire   +2 more sources

A study of the prostate, androgens and sexual activity of male rats

open access: yesReproductive Biology and Endocrinology, 2007
Background The prostate is a sexual gland that produces important substances for the potency of sperm to fertilize eggs within the female reproductive tract, and is under complex endocrine control.
Garcia Luis I   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy